Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0036211 | biological_process | protein modification process |
| B | 0036211 | biological_process | protein modification process |
| C | 0036211 | biological_process | protein modification process |
| D | 0036211 | biological_process | protein modification process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue S3A A 601 |
| Chain | Residue |
| A | TYR69 |
| A | LYS283 |
| A | ASP346 |
| A | GLU359 |
| A | ASN361 |
| A | HIS362 |
| A | SER363 |
| A | PRO364 |
| A | SER365 |
| A | LYS377 |
| A | ADP602 |
| A | CYS179 |
| A | MG603 |
| A | MG604 |
| A | HOH714 |
| A | HOH719 |
| A | HOH721 |
| A | HOH722 |
| A | HOH726 |
| A | HOH749 |
| C | LYS194 |
| A | GLN180 |
| A | ARG219 |
| A | LEU239 |
| A | ARG241 |
| A | ASN264 |
| A | TYR265 |
| A | SER266 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | binding site for residue ADP A 602 |
| Chain | Residue |
| A | LYS125 |
| A | ILE172 |
| A | LYS174 |
| A | CYS179 |
| A | GLN180 |
| A | GLY181 |
| A | ILE184 |
| A | GLN202 |
| A | LEU203 |
| A | TYR204 |
| A | ILE205 |
| A | LYS215 |
| A | ASP217 |
| A | LEU262 |
| A | THR263 |
| A | ASN264 |
| A | ASP346 |
| A | LEU348 |
| A | LEU358 |
| A | GLU359 |
| A | S3A601 |
| A | MG603 |
| A | MG604 |
| A | HOH714 |
| A | HOH719 |
| A | HOH754 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 603 |
| Chain | Residue |
| A | GLU359 |
| A | ASN361 |
| A | S3A601 |
| A | ADP602 |
| A | HOH714 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 604 |
| Chain | Residue |
| A | ASN264 |
| A | ASP346 |
| A | GLU359 |
| A | S3A601 |
| A | ADP602 |
| A | HOH719 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 605 |
| Chain | Residue |
| A | GLY181 |
| A | ARG182 |
| A | GLY183 |
| A | ILE184 |
| A | LEU262 |
| C | PHE185 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 606 |
| Chain | Residue |
| A | SER133 |
| A | ARG148 |
| A | THR149 |
| A | TRP150 |
| A | ASP158 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 607 |
| Chain | Residue |
| A | GLU301 |
| A | ARG305 |
| A | ARG445 |
| A | HOH770 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 608 |
| Chain | Residue |
| A | TYR69 |
| A | ASP70 |
| A | SER367 |
| A | THR368 |
| A | HOH751 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 609 |
| Chain | Residue |
| A | GLN78 |
| A | TYR382 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 610 |
| Chain | Residue |
| A | PRO208 |
| A | PHE209 |
| A | ILE210 |
| A | ARG351 |
| A | HOH709 |
| A | HOH800 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 611 |
| Chain | Residue |
| A | SER282 |
| A | ARG284 |
| A | PHE214 |
| A | ALA243 |
| A | THR244 |
| A | ASN273 |
| A | SER280 |
| A | GLY281 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 612 |
| Chain | Residue |
| A | ASP142 |
| A | ASP309 |
| A | LYS313 |
| A | LYS455 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 613 |
| Chain | Residue |
| A | ASP299 |
| A | GLN302 |
| A | ARG305 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 614 |
| Chain | Residue |
| A | GLN78 |
| A | ASP378 |
| A | HOH772 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 615 |
| Chain | Residue |
| A | PRO175 |
| A | GLY183 |
| A | ASP198 |
| A | MET199 |
| A | HOH706 |
| C | PRO175 |
| C | GLY183 |
| C | HOH751 |
| site_id | AD7 |
| Number of Residues | 11 |
| Details | binding site for residue S37 A 616 |
| Chain | Residue |
| A | PRO147 |
| A | ARG148 |
| A | TYR162 |
| A | LYS169 |
| A | LEU203 |
| A | TYR204 |
| A | ILE205 |
| A | SER206 |
| A | LYS207 |
| A | ASP350 |
| A | TRP356 |
| site_id | AD8 |
| Number of Residues | 26 |
| Details | binding site for residue S3A B 601 |
| Chain | Residue |
| B | CYS179 |
| B | GLN180 |
| B | ARG219 |
| B | LEU239 |
| B | ARG241 |
| B | ASN264 |
| B | TYR265 |
| B | SER266 |
| B | LYS283 |
| B | ASP346 |
| B | GLU359 |
| B | ASN361 |
| B | HIS362 |
| B | SER363 |
| B | PRO364 |
| B | SER365 |
| B | LYS377 |
| B | ADP602 |
| B | MG603 |
| B | MG604 |
| B | HOH713 |
| B | HOH723 |
| B | HOH724 |
| B | HOH776 |
| B | HOH779 |
| D | LYS194 |
| site_id | AD9 |
| Number of Residues | 26 |
| Details | binding site for residue ADP B 602 |
| Chain | Residue |
| B | LYS125 |
| B | ILE172 |
| B | LYS174 |
| B | CYS179 |
| B | GLN180 |
| B | GLY181 |
| B | ILE184 |
| B | GLN202 |
| B | LEU203 |
| B | TYR204 |
| B | ILE205 |
| B | LYS215 |
| B | ASP217 |
| B | LEU262 |
| B | THR263 |
| B | ASN264 |
| B | ASP346 |
| B | LEU348 |
| B | LEU358 |
| B | GLU359 |
| B | S3A601 |
| B | MG603 |
| B | MG604 |
| B | HOH713 |
| B | HOH724 |
| B | HOH750 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 603 |
| Chain | Residue |
| B | ASP346 |
| B | GLU359 |
| B | S3A601 |
| B | ADP602 |
| B | HOH713 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 604 |
| Chain | Residue |
| B | GLU359 |
| B | ASN361 |
| B | S3A601 |
| B | ADP602 |
| B | HOH724 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 605 |
| Chain | Residue |
| B | GLU301 |
| B | ARG305 |
| B | ARG445 |
| B | HOH707 |
| B | HOH792 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 606 |
| Chain | Residue |
| B | ARG68 |
| B | TYR69 |
| B | ASP70 |
| B | SER367 |
| B | HOH766 |
| B | HOH781 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 607 |
| Chain | Residue |
| B | ARG148 |
| B | THR149 |
| B | ASP155 |
| B | ASP158 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 608 |
| Chain | Residue |
| B | PRO208 |
| B | PHE209 |
| B | ILE210 |
| B | ARG351 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 609 |
| Chain | Residue |
| B | GLN78 |
| B | TYR382 |
| B | GOL610 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 610 |
| Chain | Residue |
| B | SER379 |
| B | TYR382 |
| B | ASP383 |
| B | GOL609 |
| B | HOH710 |
| B | HOH735 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 611 |
| Chain | Residue |
| B | ALA278 |
| B | PHE279 |
| B | LYS285 |
| B | THR288 |
| B | HOH716 |
| B | HOH718 |
| B | HOH784 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 612 |
| Chain | Residue |
| B | LYS207 |
| B | PRO208 |
| B | ILE210 |
| site_id | AF2 |
| Number of Residues | 26 |
| Details | binding site for residue S3A C 601 |
| Chain | Residue |
| A | LYS194 |
| C | CYS179 |
| C | GLN180 |
| C | ARG219 |
| C | LEU239 |
| C | ARG241 |
| C | ASN264 |
| C | TYR265 |
| C | SER266 |
| C | LYS283 |
| C | ASP346 |
| C | GLU359 |
| C | ASN361 |
| C | HIS362 |
| C | SER363 |
| C | PRO364 |
| C | SER365 |
| C | LYS377 |
| C | ADP602 |
| C | MG603 |
| C | MG604 |
| C | HOH725 |
| C | HOH726 |
| C | HOH736 |
| C | HOH768 |
| C | HOH796 |
| site_id | AF3 |
| Number of Residues | 25 |
| Details | binding site for residue ADP C 602 |
| Chain | Residue |
| C | LYS125 |
| C | ILE172 |
| C | LYS174 |
| C | CYS179 |
| C | GLN180 |
| C | GLY181 |
| C | ILE184 |
| C | GLN202 |
| C | LEU203 |
| C | TYR204 |
| C | ILE205 |
| C | LYS215 |
| C | ASP217 |
| C | LEU262 |
| C | THR263 |
| C | ASN264 |
| C | ASP346 |
| C | LEU348 |
| C | LEU358 |
| C | GLU359 |
| C | S3A601 |
| C | MG603 |
| C | MG604 |
| C | HOH726 |
| C | HOH769 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 603 |
| Chain | Residue |
| C | GLU359 |
| C | ASN361 |
| C | S3A601 |
| C | ADP602 |
| C | HOH725 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 604 |
| Chain | Residue |
| C | ASP346 |
| C | GLU359 |
| C | S3A601 |
| C | ADP602 |
| C | HOH726 |
| site_id | AF6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 605 |
| Chain | Residue |
| C | ARG68 |
| C | ASP70 |
| C | SER367 |
| C | HOH742 |
| C | HOH774 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 606 |
| Chain | Residue |
| A | PHE185 |
| A | ASP256 |
| C | GLY181 |
| C | ARG182 |
| C | GLY183 |
| C | ILE184 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 607 |
| Chain | Residue |
| C | GLN78 |
| C | ASP378 |
| C | HOH780 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 608 |
| Chain | Residue |
| C | GLU301 |
| C | ARG305 |
| C | ARG445 |
| C | HOH704 |
| C | HOH776 |
| site_id | AG1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 609 |
| Chain | Residue |
| C | ARG305 |
| C | GLU308 |
| C | ILE447 |
| C | ASN452 |
| C | TYR456 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 610 |
| Chain | Residue |
| C | PHE209 |
| C | ILE210 |
| C | ARG351 |
| C | HOH724 |
| site_id | AG3 |
| Number of Residues | 28 |
| Details | binding site for residue S3A D 601 |
| Chain | Residue |
| B | LYS194 |
| D | TYR69 |
| D | CYS179 |
| D | GLN180 |
| D | ARG219 |
| D | LEU239 |
| D | ARG241 |
| D | ASN264 |
| D | TYR265 |
| D | SER266 |
| D | LYS283 |
| D | ASP346 |
| D | GLU359 |
| D | ASN361 |
| D | HIS362 |
| D | SER363 |
| D | PRO364 |
| D | SER365 |
| D | LYS377 |
| D | ADP602 |
| D | MG603 |
| D | MG604 |
| D | HOH709 |
| D | HOH715 |
| D | HOH719 |
| D | HOH729 |
| D | HOH739 |
| D | HOH767 |
| site_id | AG4 |
| Number of Residues | 26 |
| Details | binding site for residue ADP D 602 |
| Chain | Residue |
| D | LYS125 |
| D | ILE172 |
| D | LYS174 |
| D | CYS179 |
| D | GLN180 |
| D | GLY181 |
| D | ILE184 |
| D | GLN202 |
| D | LEU203 |
| D | TYR204 |
| D | ILE205 |
| D | LYS215 |
| D | ASP217 |
| D | LEU262 |
| D | THR263 |
| D | ASN264 |
| D | ASP346 |
| D | LEU348 |
| D | LEU358 |
| D | GLU359 |
| D | S3A601 |
| D | MG603 |
| D | MG604 |
| D | HOH709 |
| D | HOH739 |
| D | HOH745 |
| site_id | AG5 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 603 |
| Chain | Residue |
| D | ASP346 |
| D | GLU359 |
| D | S3A601 |
| D | ADP602 |
| D | HOH739 |
| site_id | AG6 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 604 |
| Chain | Residue |
| D | GLU359 |
| D | ASN361 |
| D | S3A601 |
| D | ADP602 |
| D | HOH709 |
| site_id | AG7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 605 |
| Chain | Residue |
| D | ASN290 |
| D | GLU301 |
| D | ARG305 |
| D | ARG445 |
| D | HOH798 |
| site_id | AG8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 606 |
| Chain | Residue |
| D | ARG68 |
| D | TYR69 |
| D | ASP70 |
| D | SER367 |
| D | HOH764 |
| site_id | AG9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 607 |
| Chain | Residue |
| D | ASP142 |
| D | ASP309 |
| D | LYS313 |
| D | LYS455 |
| D | TYR456 |
| site_id | AH1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 608 |
| Chain | Residue |
| D | TYR265 |
| D | PHE274 |
| D | GLN276 |
| D | HOH810 |
| site_id | AH2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 609 |
| Chain | Residue |
| B | PRO175 |
| B | ASP198 |
| D | PRO175 |
| D | ASP198 |
| D | MET199 |
| D | HOH727 |
| D | HOH777 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 610 |
| Chain | Residue |
| D | GLU301 |
| D | GLN302 |
| D | ARG305 |
| D | HOH712 |
| D | HOH723 |
| site_id | AH4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 611 |
| Chain | Residue |
| D | LYS207 |
| D | PRO208 |
| D | ILE210 |
| D | TYR247 |
| site_id | AH5 |
| Number of Residues | 11 |
| Details | binding site for residue S37 D 612 |
| Chain | Residue |
| D | PRO147 |
| D | ARG148 |
| D | TYR162 |
| D | LYS169 |
| D | LEU203 |
| D | TYR204 |
| D | ILE205 |
| D | SER206 |
| D | LYS207 |
| D | ASP350 |
| D | TRP356 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS174 | |
| C | GLN202 | |
| C | LYS215 | |
| C | THR263 | |
| D | LYS174 | |
| D | GLN202 | |
| D | LYS215 | |
| D | THR263 | |
| A | GLN202 | |
| A | LYS215 | |
| A | THR263 | |
| B | LYS174 | |
| B | GLN202 | |
| B | LYS215 | |
| B | THR263 | |
| C | LYS174 | |
| Chain | Residue | Details |
| A | GLN180 | |
| A | HIS362 | |
| B | GLN180 | |
| B | HIS362 | |
| C | GLN180 | |
| C | HIS362 | |
| D | GLN180 | |
| D | HIS362 | |
| Chain | Residue | Details |
| A | ARG241 | |
| B | LYS377 | |
| C | ARG241 | |
| C | TYR265 | |
| C | SER266 | |
| C | LYS283 | |
| C | LYS377 | |
| D | ARG241 | |
| D | TYR265 | |
| D | SER266 | |
| D | LYS283 | |
| A | TYR265 | |
| D | LYS377 | |
| A | SER266 | |
| A | LYS283 | |
| A | LYS377 | |
| B | ARG241 | |
| B | TYR265 | |
| B | SER266 | |
| B | LYS283 | |
| Chain | Residue | Details |
| A | ASP346 | |
| D | ASP346 | |
| D | GLU359 | |
| D | ASN361 | |
| A | GLU359 | |
| A | ASN361 | |
| B | ASP346 | |
| B | GLU359 | |
| B | ASN361 | |
| C | ASP346 | |
| C | GLU359 | |
| C | ASN361 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | SITE: Essential for specifying alpha-elongation versus initiation step of the polyglutamylase activity => ECO:0000269|PubMed:32747782 |
| Chain | Residue | Details |
| A | GLN180 | |
| B | GLN180 | |
| C | GLN180 | |
| D | GLN180 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | SITE: Important for specifying alpha-elongation versus initiation step of the polyglutamylase activity => ECO:0000269|PubMed:32747782 |
| Chain | Residue | Details |
| A | HIS362 | |
| B | HIS362 | |
| C | HIS362 | |
| D | HIS362 | |
