Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0036211 | biological_process | protein modification process |
| B | 0036211 | biological_process | protein modification process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue ATP A 601 |
| Chain | Residue |
| A | ILE172 |
| A | ILE205 |
| A | LYS215 |
| A | ASP217 |
| A | THR263 |
| A | ASN264 |
| A | LEU358 |
| A | GLU359 |
| A | MG609 |
| A | HOH705 |
| A | HOH735 |
| A | LYS174 |
| A | HOH736 |
| A | CYS179 |
| A | GLN180 |
| A | GLY181 |
| A | ILE184 |
| A | GLN202 |
| A | LEU203 |
| A | TYR204 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 602 |
| Chain | Residue |
| A | ASN290 |
| A | GLU301 |
| A | ARG305 |
| A | ARG445 |
| A | HOH725 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 603 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 604 |
| Chain | Residue |
| A | SER133 |
| A | THR149 |
| A | TRP150 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 605 |
| Chain | Residue |
| A | ASP228 |
| A | LEU230 |
| A | HIS319 |
| A | LYS323 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 606 |
| Chain | Residue |
| A | GLN180 |
| A | ARG219 |
| A | ARG241 |
| A | ASN264 |
| A | TYR265 |
| A | SER266 |
| A | HOH735 |
| A | HOH736 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 607 |
| Chain | Residue |
| A | ARG219 |
| A | LEU239 |
| A | ARG241 |
| A | TYR265 |
| A | LYS283 |
| A | LYS377 |
| A | HOH728 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 608 |
| Chain | Residue |
| A | SER98 |
| A | VAL99 |
| A | GLY118 |
| A | MET119 |
| A | SER120 |
| A | HOH743 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 609 |
| Chain | Residue |
| A | ATP601 |
| A | HOH705 |
| A | HOH735 |
| A | HOH736 |
| site_id | AD1 |
| Number of Residues | 23 |
| Details | binding site for residue ATP B 601 |
| Chain | Residue |
| B | LYS125 |
| B | ILE172 |
| B | LYS174 |
| B | GLY178 |
| B | CYS179 |
| B | GLN180 |
| B | GLY181 |
| B | ILE184 |
| B | GLN202 |
| B | LEU203 |
| B | TYR204 |
| B | ILE205 |
| B | LYS215 |
| B | ASP217 |
| B | THR263 |
| B | ASN264 |
| B | LEU348 |
| B | LEU358 |
| B | GLU359 |
| B | MG613 |
| B | HOH702 |
| B | HOH704 |
| B | HOH717 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 602 |
| Chain | Residue |
| A | LYS269 |
| B | TYR69 |
| B | GLN180 |
| B | LYS269 |
| B | SER365 |
| B | SER367 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 603 |
| Chain | Residue |
| B | ILE205 |
| B | TRP356 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 604 |
| Chain | Residue |
| A | SER177 |
| B | ASP256 |
| B | GLU257 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue GOL B 605 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 606 |
| Chain | Residue |
| B | LYS323 |
| B | CYS227 |
| B | ASP228 |
| B | PRO229 |
| B | LEU230 |
| B | HIS319 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 607 |
| Chain | Residue |
| B | LYS57 |
| B | LYS58 |
| B | ARG59 |
| B | ARG82 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 608 |
| Chain | Residue |
| B | GLN180 |
| B | ARG219 |
| B | ARG241 |
| B | ASN264 |
| B | TYR265 |
| B | SER266 |
| B | HOH702 |
| B | HOH717 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 609 |
| Chain | Residue |
| B | ARG219 |
| B | LEU239 |
| B | ARG241 |
| B | TYR265 |
| B | LYS283 |
| B | LYS377 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 610 |
| Chain | Residue |
| B | SER98 |
| B | VAL99 |
| B | PRO117 |
| B | GLY118 |
| B | MET119 |
| B | SER120 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 611 |
| Chain | Residue |
| B | GLU301 |
| B | TRP304 |
| B | ARG445 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 612 |
| Chain | Residue |
| A | ASP70 |
| A | ARG74 |
| B | ASP70 |
| B | ARG74 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 613 |
| Chain | Residue |
| B | ATP601 |
| B | HOH702 |
| B | HOH704 |
| B | HOH717 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS174 | |
| A | GLN202 | |
| A | LYS215 | |
| A | THR263 | |
| B | LYS174 | |
| B | GLN202 | |
| B | LYS215 | |
| B | THR263 | |
| Chain | Residue | Details |
| A | GLN180 | |
| A | HIS362 | |
| B | GLN180 | |
| B | HIS362 | |
| Chain | Residue | Details |
| A | ARG241 | |
| B | LYS377 | |
| A | TYR265 | |
| A | SER266 | |
| A | LYS283 | |
| A | LYS377 | |
| B | ARG241 | |
| B | TYR265 | |
| B | SER266 | |
| B | LYS283 | |
| Chain | Residue | Details |
| A | ASP346 | |
| A | GLU359 | |
| A | ASN361 | |
| B | ASP346 | |
| B | GLU359 | |
| B | ASN361 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Essential for specifying alpha-elongation versus initiation step of the polyglutamylase activity => ECO:0000269|PubMed:32747782 |
| Chain | Residue | Details |
| A | GLN180 | |
| B | GLN180 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Important for specifying alpha-elongation versus initiation step of the polyglutamylase activity => ECO:0000269|PubMed:32747782 |
| Chain | Residue | Details |
| A | HIS362 | |
| B | HIS362 | |
