6VWY

Crystal structure of C45G/T50C D. vulgaris carbon monoxide dehydrogenase (anaerobic)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004601	molecular_function	peroxidase activity
A	0006091	biological_process	generation of precursor metabolites and energy
A	0016151	molecular_function	nickel cation binding
A	0016491	molecular_function	oxidoreductase activity
A	0042542	biological_process	response to hydrogen peroxide
A	0043885	molecular_function	anaerobic carbon-monoxide dehydrogenase activity
A	0050418	molecular_function	hydroxylamine reductase activity
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0098869	biological_process	cellular oxidant detoxification
B	0003824	molecular_function	catalytic activity
B	0004601	molecular_function	peroxidase activity
B	0006091	biological_process	generation of precursor metabolites and energy
B	0016151	molecular_function	nickel cation binding
B	0016491	molecular_function	oxidoreductase activity
B	0042542	biological_process	response to hydrogen peroxide
B	0043885	molecular_function	anaerobic carbon-monoxide dehydrogenase activity
B	0050418	molecular_function	hydroxylamine reductase activity
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue SF4 A 701

Chain	Residue
A	CYS51
A	ASN53
A	CYS54
A	GLY57
A	CYS59
A	CYS74
A	ARG84
A	MET203

---

site_id	AC2
Number of Residues	6
Details	binding site for residue SF4 A 702

Chain	Residue
A	GLY45
A	CYS50
B	CYS42
B	GLY45
B	CYS50
A	CYS42

---

site_id	AC3
Number of Residues	12
Details	binding site for residue XCC A 703

Chain	Residue
A	HIS266
A	CYS301
A	CYS302
A	HIS319
A	CYS340
A	GLY447
A	CYS448
A	CYS478
A	CYS519
A	TYR553
A	SER554
A	LYS556

---

site_id	AC5
Number of Residues	9
Details	binding site for residue GOL A 705

Chain	Residue
A	PRO570
A	GLN594
A	GLY598
A	HIS617
A	ARG621
A	ARG624
A	HOH823
A	HOH847
B	ASP595

---

site_id	AC6
Number of Residues	6
Details	binding site for residue GOL A 706

Chain	Residue
A	ASP79
A	GLY581
A	SER582
A	GLU583
A	ASN584
A	HOH1009

---

site_id	AC7
Number of Residues	8
Details	binding site for residue GOL A 707

Chain	Residue
A	GLY184
A	ARG200
A	SER211
A	VAL214
A	ARG218
A	HOH1018
B	PRO361
B	HOH916

---

site_id	AC8
Number of Residues	8
Details	binding site for residue SF4 B 701

Chain	Residue
B	CYS51
B	ASN53
B	CYS54
B	GLY57
B	CYS59
B	CYS74
B	ARG84
B	MET203

---

site_id	AC9
Number of Residues	11
Details	binding site for residue XCC B 702

Chain	Residue
B	HIS266
B	CYS301
B	CYS302
B	CYS340
B	GLY447
B	CYS448
B	CYS478
B	CYS519
B	TYR553
B	SER554
B	LYS556

---

site_id	AD2
Number of Residues	9
Details	binding site for residue GOL B 704

Chain	Residue
A	ASP595
B	PRO570
B	GLN594
B	GLY598
B	HIS617
B	ARG621
B	ARG624
B	HOH848
B	HOH935

---

site_id	AD3
Number of Residues	6
Details	binding site for residue GOL B 705

Chain	Residue
B	ASP79
B	GLY581
B	SER582
B	GLU583
B	ASN584
B	HOH946

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Motif: {"description":"CXXC; D cluster binding","evidences":[{"source":"PubMed","id":"30277213","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32655979","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30277213","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31296570","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6B6V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B6X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B6Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ONC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OND","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR005023-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30277213","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31296570","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35278753","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6B6V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B6X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B6Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ONC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OND","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ONS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TSJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR005023-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30277213","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32655979","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6B6V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B6X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6VWY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Site: {"description":"Binds C cluster in the oxidized state, but not in the canonical reduced state","evidences":[{"source":"PubMed","id":"30277213","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---