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6VU5

Structure of G-alpha-q bound to its chaperone Ric-8A

Functional Information from GO Data
ChainGOidnamespacecontents
B0000166molecular_functionnucleotide binding
B0001664molecular_functionG protein-coupled receptor binding
B0001750cellular_componentphotoreceptor outer segment
B0003924molecular_functionGTPase activity
B0003925molecular_functionG protein activity
B0005096molecular_functionGTPase activator activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005765cellular_componentlysosomal membrane
B0005794cellular_componentGolgi apparatus
B0005834cellular_componentheterotrimeric G-protein complex
B0005886cellular_componentplasma membrane
B0007165biological_processsignal transduction
B0007186biological_processG protein-coupled receptor signaling pathway
B0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
B0007200biological_processphospholipase C-activating G protein-coupled receptor signaling pathway
B0007206biological_processphospholipase C-activating G protein-coupled glutamate receptor signaling pathway
B0007208biological_processphospholipase C-activating serotonin receptor signaling pathway
B0007213biological_processG protein-coupled acetylcholine receptor signaling pathway
B0007215biological_processglutamate receptor signaling pathway
B0007218biological_processneuropeptide signaling pathway
B0007596biological_processblood coagulation
B0007603biological_processphototransduction, visible light
B0009649biological_processentrainment of circadian clock
B0009755biological_processhormone-mediated signaling pathway
B0010543biological_processregulation of platelet activation
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0019001molecular_functionguanyl nucleotide binding
B0030234molecular_functionenzyme regulator activity
B0031683molecular_functionG-protein beta/gamma-subunit complex binding
B0031965cellular_componentnuclear membrane
B0034695biological_processresponse to prostaglandin E
B0046872molecular_functionmetal ion binding
B0050821biological_processprotein stabilization
B0060828biological_processregulation of canonical Wnt signaling pathway
B0070062cellular_componentextracellular exosome
B0071468biological_processcellular response to acidic pH
B0099524cellular_componentpostsynaptic cytosol
B0140582biological_processadenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine; by CK2 => ECO:0000269|PubMed:29844055, ECO:0000269|PubMed:32103024, ECO:0000269|PubMed:32126208
ChainResidueDetails
ASEP435
BTHR186
BASN274
BLYS275
BASP277
BALA331
BGLY51
BLYS52
BSER53
BTHR54
BSER156
BLEU180
BARG181
BARG183

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by CK2 => ECO:0000269|PubMed:29844055, ECO:0000269|PubMed:32103024, ECO:0000269|PubMed:32126208
ChainResidueDetails
ATPO440

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q3TIR3
ChainResidueDetails
ATHR442
BCYS10

237735

PDB entries from 2025-06-18

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