6VS4

Crystal structure of ADP RIBOSYLATION FACTOR-LIKE GTP BINDING PROTEIN /Small COPII coat GTPase SAR1 from Encephalitozoon cuniculi in complex with GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0003400	biological_process	regulation of COPII vesicle coating
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0006886	biological_process	intracellular protein transport
A	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
A	0012507	cellular_component	ER to Golgi transport vesicle membrane
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0016050	biological_process	vesicle organization
A	0016192	biological_process	vesicle-mediated transport
A	0016787	molecular_function	hydrolase activity
A	0030127	cellular_component	COPII vesicle coat
A	0031410	cellular_component	cytoplasmic vesicle
A	0061024	biological_process	membrane organization
A	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
A	0070971	cellular_component	endoplasmic reticulum exit site
B	0000139	cellular_component	Golgi membrane
B	0003400	biological_process	regulation of COPII vesicle coating
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0006886	biological_process	intracellular protein transport
B	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
B	0012507	cellular_component	ER to Golgi transport vesicle membrane
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0016050	biological_process	vesicle organization
B	0016192	biological_process	vesicle-mediated transport
B	0016787	molecular_function	hydrolase activity
B	0030127	cellular_component	COPII vesicle coat
B	0031410	cellular_component	cytoplasmic vesicle
B	0061024	biological_process	membrane organization
B	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
B	0070971	cellular_component	endoplasmic reticulum exit site

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue PEG A 301

Chain	Residue
A	LYS13
B	THR17
B	TYR20
B	GLY192

---

site_id	AC2
Number of Residues	18
Details	binding site for residue GDP A 302

Chain	Residue
A	THR49
A	THR50
A	ASP85
A	ASN142
A	LYS143
A	ASP145
A	LEU146
A	THR188
A	ILE189
A	THR190
A	MG303
A	HOH404
A	HOH410
A	ASP44
A	ASN45
A	ALA46
A	GLY47
A	LYS48

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MG A 303

Chain	Residue
A	THR49
A	GDP302
A	HOH404
A	HOH410

---

site_id	AC4
Number of Residues	3
Details	binding site for residue PEG B 301

Chain	Residue
A	TYR20
A	GLY192
B	LYS13

---

site_id	AC5
Number of Residues	4
Details	binding site for residue PEG B 302

Chain	Residue
A	GLU147
A	GLY148
B	HIS89
B	THR90

---

site_id	AC6
Number of Residues	19
Details	binding site for residue GDP B 303

Chain	Residue
B	ASP44
B	ASN45
B	ALA46
B	GLY47
B	LYS48
B	THR49
B	THR50
B	ASN142
B	LYS143
B	ASP145
B	LEU146
B	THR188
B	ILE189
B	THR190
B	MG304
B	HOH401
B	HOH418
B	HOH421
B	HOH437

---

site_id	AC7
Number of Residues	6
Details	binding site for residue MG B 304

Chain	Residue
B	THR49
B	GDP303
B	HOH401
B	HOH412
B	HOH418
B	HOH421

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	LYS48
A	ALA91
A	PRO151
B	LYS48
B	ALA91
B	PRO151

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