6VQJ

Mammalian V-ATPase from rat brain collar and peripheral stalks rotational state 2 (from focused refinement)

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
a	0005737	cellular_component	cytoplasm
a	0005886	cellular_component	plasma membrane
a	0007035	biological_process	vacuolar acidification
a	0008150	biological_process	biological_process
a	0016020	cellular_component	membrane
a	0016241	biological_process	regulation of macroautophagy
a	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
a	0030665	cellular_component	clathrin-coated vesicle membrane
a	0030672	cellular_component	synaptic vesicle membrane
a	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
a	0042470	cellular_component	melanosome
a	0043195	cellular_component	terminal bouton
a	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
a	0048471	cellular_component	perinuclear region of cytoplasm
a	0051117	molecular_function	ATPase binding
a	0097401	biological_process	synaptic vesicle lumen acidification
a	1902600	biological_process	proton transmembrane transport
G	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
G	0005886	cellular_component	plasma membrane
G	0008150	biological_process	biological_process
G	0015078	molecular_function	proton transmembrane transporter activity
G	0016020	cellular_component	membrane
G	0030665	cellular_component	clathrin-coated vesicle membrane
G	0030672	cellular_component	synaptic vesicle membrane
G	0033176	cellular_component	proton-transporting V-type ATPase complex
G	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
G	0045177	cellular_component	apical part of cell
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	0097401	biological_process	synaptic vesicle lumen acidification
G	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
G	1902600	biological_process	proton transmembrane transport
I	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
I	0005737	cellular_component	cytoplasm
I	0005765	cellular_component	lysosomal membrane
I	0005768	cellular_component	endosome
I	0005829	cellular_component	cytosol
I	0005902	cellular_component	microvillus
I	0016324	cellular_component	apical plasma membrane
I	0030665	cellular_component	clathrin-coated vesicle membrane
I	0030672	cellular_component	synaptic vesicle membrane
I	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
I	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	0051117	molecular_function	ATPase binding
I	0071230	biological_process	cellular response to amino acid stimulus
I	0097401	biological_process	synaptic vesicle lumen acidification
I	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
I	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
I	1902600	biological_process	proton transmembrane transport
I	1904263	biological_process	positive regulation of TORC1 signaling
J	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
J	0005737	cellular_component	cytoplasm
J	0005765	cellular_component	lysosomal membrane
J	0005768	cellular_component	endosome
J	0005829	cellular_component	cytosol
J	0005902	cellular_component	microvillus
J	0016324	cellular_component	apical plasma membrane
J	0030665	cellular_component	clathrin-coated vesicle membrane
J	0030672	cellular_component	synaptic vesicle membrane
J	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
J	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
J	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
J	0051117	molecular_function	ATPase binding
J	0071230	biological_process	cellular response to amino acid stimulus
J	0097401	biological_process	synaptic vesicle lumen acidification
J	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
J	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
J	1902600	biological_process	proton transmembrane transport
J	1904263	biological_process	positive regulation of TORC1 signaling
K	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
K	0005737	cellular_component	cytoplasm
K	0005765	cellular_component	lysosomal membrane
K	0005768	cellular_component	endosome
K	0005829	cellular_component	cytosol
K	0005902	cellular_component	microvillus
K	0016324	cellular_component	apical plasma membrane
K	0030665	cellular_component	clathrin-coated vesicle membrane
K	0030672	cellular_component	synaptic vesicle membrane
K	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
K	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
K	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
K	0051117	molecular_function	ATPase binding
K	0071230	biological_process	cellular response to amino acid stimulus
K	0097401	biological_process	synaptic vesicle lumen acidification
K	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
K	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
K	1902600	biological_process	proton transmembrane transport
K	1904263	biological_process	positive regulation of TORC1 signaling
M	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
M	0012505	cellular_component	endomembrane system
M	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
M	0030672	cellular_component	synaptic vesicle membrane
M	0042470	cellular_component	melanosome
M	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
M	0097401	biological_process	synaptic vesicle lumen acidification
M	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
M	1902600	biological_process	proton transmembrane transport
N	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
N	0012505	cellular_component	endomembrane system
N	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
N	0030672	cellular_component	synaptic vesicle membrane
N	0042470	cellular_component	melanosome
N	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
N	0097401	biological_process	synaptic vesicle lumen acidification
N	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
N	1902600	biological_process	proton transmembrane transport
O	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
O	0012505	cellular_component	endomembrane system
O	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
O	0030672	cellular_component	synaptic vesicle membrane
O	0042470	cellular_component	melanosome
O	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
O	0097401	biological_process	synaptic vesicle lumen acidification
O	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
O	1902600	biological_process	proton transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"UniProtKB","id":"P21283","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"P36543","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P50518","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q9Z1G4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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