Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000212 | biological_process | meiotic spindle organization |
| A | 0000226 | biological_process | microtubule cytoskeleton organization |
| A | 0000278 | biological_process | mitotic cell cycle |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007052 | biological_process | mitotic spindle organization |
| A | 0007098 | biological_process | centrosome cycle |
| A | 0007100 | biological_process | mitotic centrosome separation |
| A | 0051321 | biological_process | meiotic cell cycle |
| B | 0000212 | biological_process | meiotic spindle organization |
| B | 0000226 | biological_process | microtubule cytoskeleton organization |
| B | 0000278 | biological_process | mitotic cell cycle |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0007052 | biological_process | mitotic spindle organization |
| B | 0007098 | biological_process | centrosome cycle |
| B | 0007100 | biological_process | mitotic centrosome separation |
| B | 0051321 | biological_process | meiotic cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | ASP11 |
| B | SER7 |
| B | GLU175 |
| B | HIS176 |
| B | ARG179 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue ANP A 602 |
| Chain | Residue |
| A | ALA160 |
| A | LYS162 |
| A | LEU194 |
| A | GLU211 |
| A | TYR212 |
| A | ALA213 |
| A | THR217 |
| A | ASP274 |
| A | MG604 |
| A | HOH734 |
| A | HOH842 |
| B | TPO288 |
| A | LEU139 |
| A | GLY140 |
| A | GLY142 |
| A | LYS143 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MLA A 603 |
| Chain | Residue |
| A | ARG304 |
| A | HIS366 |
| A | ASN367 |
| A | HOH805 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 604 |
| Chain | Residue |
| A | LYS162 |
| A | GLU181 |
| A | ANP602 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 605 |
| Chain | Residue |
| A | SER7 |
| A | GLU175 |
| A | HIS176 |
| A | ARG179 |
| B | ASP11 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue R7D A 606 |
| Chain | Residue |
| A | SER116 |
| A | LEU289 |
| A | CYS290 |
| A | MET300 |
| A | ILE301 |
| A | HIS306 |
| A | HOH720 |
| A | HOH793 |
| B | ARG255 |
| B | TRP277 |
| B | MET305 |
| B | TYR338 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for residue ANP B 601 |
| Chain | Residue |
| B | GLY142 |
| B | LYS143 |
| B | PHE144 |
| B | VAL147 |
| B | ALA160 |
| B | LYS162 |
| B | LEU194 |
| B | GLU211 |
| B | ALA213 |
| B | MG604 |
| B | HOH703 |
| B | HOH704 |
| B | HOH867 |
| B | HOH881 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 602 |
| Chain | Residue |
| A | TYR334 |
| B | GLY291 |
| B | THR292 |
| B | LEU293 |
| B | ASP294 |
| B | HOH707 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue MLA B 603 |
| Chain | Residue |
| A | LYS224 |
| B | ARG304 |
| B | HIS366 |
| B | ASN367 |
| B | HOH789 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 604 |
| Chain | Residue |
| B | LYS162 |
| B | GLU181 |
| B | ANP601 |
| site_id | AD2 |
| Number of Residues | 12 |
| Details | binding site for residue R7D B 605 |
| Chain | Residue |
| A | TRP277 |
| A | MET305 |
| A | TYR338 |
| B | LEU289 |
| B | CYS290 |
| B | LEU293 |
| B | MET300 |
| B | ILE301 |
| B | HIS306 |
| B | HOH713 |
| B | HOH802 |
| B | HOH837 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGKFGNVYlArekqskfi..........LALK |
| Chain | Residue | Details |
| A | LEU139-LYS162 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ViHrDIKpeNLLL |
| Chain | Residue | Details |
| A | VAL252-LEU264 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP256 | |
| B | ASP256 | |
| Chain | Residue | Details |
| A | LYS143 | |
| B | ASP274 | |
| A | LYS162 | |
| A | GLU211 | |
| A | GLU260 | |
| A | ASP274 | |
| B | LYS143 | |
| B | LYS162 | |
| B | GLU211 | |
| B | GLU260 | |
| Chain | Residue | Details |
| A | THR287 | |
| B | THR287 | |
| Chain | Residue | Details |
| A | TPO288 | |
| B | TPO288 | |
| Chain | Residue | Details |
| A | SER342 | |
| B | SER342 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS258 | |
| B | LYS258 | |
