6VLY

Crystal structure of FabI-NADH complex from Alistipes finegoldii

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A	0006633	biological_process	fatty acid biosynthetic process
B	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B	0006633	biological_process	fatty acid biosynthetic process
C	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C	0006633	biological_process	fatty acid biosynthetic process
D	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D	0006633	biological_process	fatty acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue GOL A 301

Chain	Residue
A	LEU157
A	TYR158
A	GLY159
A	TYR160
A	ASN161
A	HOH455
B	TYR179
C	ASP276
C	HOH417

---

site_id	AC2
Number of Residues	31
Details	binding site for residue NAI A 302

Chain	Residue
A	GLY15
A	LEU17
A	SER21
A	ILE22
A	ASN41
A	THR42
A	SER45
A	ASP66
A	ALA67
A	SER94
A	ILE95
A	ILE121
A	LEU148
A	SER149
A	TYR150
A	LYS167
A	GLN194
A	SER195
A	PRO196
A	THR197
A	THR199
A	THR200
A	ALA201
A	MET208
A	HOH421
A	HOH427
A	HOH439
A	HOH446
A	HOH458
A	HOH520
A	HOH562

---

site_id	AC3
Number of Residues	7
Details	binding site for residue GOL B 301

Chain	Residue
B	GLN20
B	THR200
B	SER203
B	GOL302
B	HOH567
D	ASN18
D	MET48

---

site_id	AC4
Number of Residues	7
Details	binding site for residue GOL B 302

Chain	Residue
B	ASN18
B	MET48
B	THR200
B	GOL301
B	HOH590
D	GLN20
D	THR200

---

site_id	AC5
Number of Residues	9
Details	binding site for residue GOL B 303

Chain	Residue
A	TYR179
B	LEU157
B	TYR158
B	GLY159
B	TYR160
B	ASN161
B	HOH422
D	ASP276
D	HOH444

---

site_id	AC6
Number of Residues	32
Details	binding site for residue NAI B 304

Chain	Residue
B	GLY15
B	LEU17
B	SER21
B	ILE22
B	ASN41
B	THR42
B	SER45
B	ASP66
B	ALA67
B	SER94
B	ILE95
B	GLY96
B	ILE121
B	LEU148
B	SER149
B	LYS167
B	GLN194
B	SER195
B	PRO196
B	THR197
B	THR199
B	THR200
B	ALA201
B	GLY202
B	MET208
B	HOH452
B	HOH465
B	HOH491
B	HOH552
B	HOH559
B	HOH583
B	HOH595

---

site_id	AC7
Number of Residues	3
Details	binding site for residue CL B 305

Chain	Residue
B	SER261
B	ARG263
C	TYR179

---

site_id	AC8
Number of Residues	9
Details	binding site for residue GOL C 301

Chain	Residue
C	SER98
C	VAL101
C	MET163
C	ALA201
C	GLY204
C	VAL205
C	HOH425
C	HOH512
C	MET97

---

site_id	AC9
Number of Residues	9
Details	binding site for residue GOL C 302

Chain	Residue
A	ASP276
A	HOH442
C	LEU157
C	TYR158
C	GLY159
C	TYR160
C	ASN161
C	HOH429
D	TYR179

---

site_id	AD1
Number of Residues	33
Details	binding site for residue NAI C 303

Chain	Residue
C	GLY15
C	LEU17
C	SER21
C	ILE22
C	ASN41
C	THR42
C	SER45
C	ASP66
C	ALA67
C	SER94
C	ILE95
C	GLY96
C	ILE121
C	LEU148
C	SER149
C	TYR150
C	LYS167
C	GLN194
C	SER195
C	PRO196
C	THR197
C	THR199
C	THR200
C	ALA201
C	GLY202
C	MET208
C	HOH424
C	HOH437
C	HOH484
C	HOH496
C	HOH515
C	HOH575
C	HOH582

---

site_id	AD2
Number of Residues	8
Details	binding site for residue GOL D 301

Chain	Residue
D	MET97
D	SER98
D	VAL101
D	MET163
D	ALA201
D	GLY204
D	VAL205
D	HOH598

---

site_id	AD3
Number of Residues	10
Details	binding site for residue GOL D 302

Chain	Residue
B	ASP276
B	HOH496
C	TYR179
D	LEU157
D	TYR158
D	GLY159
D	TYR160
D	ASN161
D	HOH402
D	HOH475

---

site_id	AD4
Number of Residues	33
Details	binding site for residue NAI D 303

Chain	Residue
D	GLY15
D	LEU17
D	SER21
D	ILE22
D	ASN41
D	THR42
D	SER45
D	ASP66
D	ALA67
D	SER94
D	ILE95
D	GLY96
D	ILE121
D	LEU148
D	SER149
D	LYS167
D	GLN194
D	SER195
D	PRO196
D	THR197
D	THR199
D	THR200
D	ALA201
D	GLY202
D	MET208
D	HOH468
D	HOH477
D	HOH497
D	HOH517
D	HOH522
D	HOH557
D	HOH563
D	HOH574

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