6VLC

Crystal structure of UDP-GlcNAc 2-epimerase from Neisseria meningitidis bound to UDP-GlcNAc

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008761	molecular_function	UDP-N-acetylglucosamine 2-epimerase activity
A	0016853	molecular_function	isomerase activity
A	0045227	biological_process	capsule polysaccharide biosynthetic process
B	0008761	molecular_function	UDP-N-acetylglucosamine 2-epimerase activity
B	0016853	molecular_function	isomerase activity
B	0045227	biological_process	capsule polysaccharide biosynthetic process
C	0008761	molecular_function	UDP-N-acetylglucosamine 2-epimerase activity
C	0016853	molecular_function	isomerase activity
C	0045227	biological_process	capsule polysaccharide biosynthetic process
D	0008761	molecular_function	UDP-N-acetylglucosamine 2-epimerase activity
D	0016853	molecular_function	isomerase activity
D	0045227	biological_process	capsule polysaccharide biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	27
Details	binding site for residue UD1 A 400

Chain	Residue
A	ARG10
A	ARG135
A	HIS212
A	GLN270
A	TYR272
A	PHE275
A	SER289
A	GLY290
A	GLY291
A	GLU295
A	ARG312
A	PRO11
A	HOH505
A	HOH509
A	HOH549
A	HOH555
A	HOH585
A	HOH597
A	HOH614
A	HOH633
A	GLU12
A	LYS15
A	HIS93
A	ASP95
A	THR96
A	GLU117
A	PRO128

---

site_id	AC2
Number of Residues	28
Details	binding site for residue UD1 C 400

Chain	Residue
C	ARG10
C	PRO11
C	GLU12
C	LYS15
C	HIS93
C	ASP95
C	GLU117
C	ARG135
C	HIS212
C	GLN270
C	TYR272
C	PHE275
C	MET279
C	SER289
C	GLY290
C	GLY291
C	GLU295
C	ARG312
C	HOH501
C	HOH522
C	HOH527
C	HOH531
C	HOH557
C	HOH573
C	HOH577
C	HOH610
C	HOH618
C	HOH634

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P27828","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---