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6VI9

Observing a ring-cleaving dioxygenase in action through a crystalline lens - an alkylperoxo bound structure

Functional Information from GO Data
ChainGOidnamespacecontents
A0000334molecular_function3-hydroxyanthranilate 3,4-dioxygenase activity
A0005506molecular_functioniron ion binding
A0006569biological_processL-tryptophan catabolic process
A0008198molecular_functionferrous iron binding
A0009435biological_processNAD+ biosynthetic process
A0016491molecular_functionoxidoreductase activity
A0019363biological_processpyridine nucleotide biosynthetic process
A0019805biological_processquinolinate biosynthetic process
A0043420biological_processanthranilate metabolic process
A0046872molecular_functionmetal ion binding
A0051213molecular_functiondioxygenase activity
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue FE2 A 301
ChainResidue
ACYS125
ACYS128
ACYS162
ACYS165

site_idAC2
Number of Residues10
Detailsbinding site for residue QXM A 302
ChainResidue
AHIS95
APRO97
AARG99
AGLU110
AHOH408
AVAL41
AARG47
AHIS51
AGLU57
APHE59

site_idAC3
Number of Residues7
Detailsbinding site for residue TRS A 303
ChainResidue
AVAL132
AHIS133
AASP158
ALYS159
AARG161
APRO163
AHOH430

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues10
DetailsBinding site: {}
ChainResidueDetails

246333

PDB entries from 2025-12-17

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