6VI7

Probing extradiol dioxygenase mechanism in NAD(+) biosynthesis by viewing reaction cycle intermediates - a substrate bidentately bound structure

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000334	molecular_function	3-hydroxyanthranilate 3,4-dioxygenase activity
A	0005506	molecular_function	iron ion binding
A	0006569	biological_process	L-tryptophan catabolic process
A	0008198	molecular_function	ferrous iron binding
A	0009435	biological_process	NAD+ biosynthetic process
A	0019805	biological_process	quinolinate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue 3HA A 201

Chain	Residue
A	VAL25
A	GLU110
A	ILE142
A	FE2202
A	ASN27
A	VAL41
A	ARG47
A	HIS51
A	GLU57
A	PHE59
A	PRO97
A	ARG99

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site_id	AC2
Number of Residues	4
Details	binding site for residue FE2 A 202

Chain	Residue
A	HIS51
A	GLU57
A	HIS95
A	3HA201

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site_id	AC3
Number of Residues	4
Details	binding site for residue FE2 A 203

Chain	Residue
A	CYS125
A	CYS128
A	CYS162
A	CYS165

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site_id	AC4
Number of Residues	6
Details	binding site for residue TRS A 204

Chain	Residue
A	VAL132
A	HIS133
A	ASP158
A	LYS159
A	ARG161
A	PRO163

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Binding site: {}

Chain

Residue

Details

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