6VGJ

N-terminal variant of CXCL13

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002467	biological_process	germinal center formation
A	0002518	biological_process	lymphocyte chemotaxis across high endothelial venule
A	0002544	biological_process	chronic inflammatory response
A	0002920	biological_process	regulation of humoral immune response
A	0005125	molecular_function	cytokine activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006935	biological_process	chemotaxis
A	0006952	biological_process	defense response
A	0006954	biological_process	inflammatory response
A	0006955	biological_process	immune response
A	0007166	biological_process	cell surface receptor signaling pathway
A	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
A	0007267	biological_process	cell-cell signaling
A	0008009	molecular_function	chemokine activity
A	0008201	molecular_function	heparin binding
A	0010820	biological_process	positive regulation of T cell chemotaxis
A	0017134	molecular_function	fibroblast growth factor binding
A	0030593	biological_process	neutrophil chemotaxis
A	0031724	molecular_function	CXCR5 chemokine receptor binding
A	0031735	molecular_function	CCR10 chemokine receptor binding
A	0032487	biological_process	regulation of Rap protein signal transduction
A	0033625	biological_process	positive regulation of integrin activation
A	0033634	biological_process	positive regulation of cell-cell adhesion mediated by integrin
A	0035754	biological_process	B cell chemotaxis
A	0035768	biological_process	endothelial cell chemotaxis to fibroblast growth factor
A	0042742	biological_process	defense response to bacterium
A	0045236	molecular_function	CXCR chemokine receptor binding
A	0045765	biological_process	regulation of angiogenesis
A	0048018	molecular_function	receptor ligand activity
A	0048248	molecular_function	CXCR3 chemokine receptor binding
A	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
A	0070098	biological_process	chemokine-mediated signaling pathway
A	0071222	biological_process	cellular response to lipopolysaccharide
A	2000545	biological_process	negative regulation of endothelial cell chemotaxis to fibroblast growth factor
B	0002467	biological_process	germinal center formation
B	0002518	biological_process	lymphocyte chemotaxis across high endothelial venule
B	0002544	biological_process	chronic inflammatory response
B	0002920	biological_process	regulation of humoral immune response
B	0005125	molecular_function	cytokine activity
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006935	biological_process	chemotaxis
B	0006952	biological_process	defense response
B	0006954	biological_process	inflammatory response
B	0006955	biological_process	immune response
B	0007166	biological_process	cell surface receptor signaling pathway
B	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
B	0007267	biological_process	cell-cell signaling
B	0008009	molecular_function	chemokine activity
B	0008201	molecular_function	heparin binding
B	0010820	biological_process	positive regulation of T cell chemotaxis
B	0017134	molecular_function	fibroblast growth factor binding
B	0030593	biological_process	neutrophil chemotaxis
B	0031724	molecular_function	CXCR5 chemokine receptor binding
B	0031735	molecular_function	CCR10 chemokine receptor binding
B	0032487	biological_process	regulation of Rap protein signal transduction
B	0033625	biological_process	positive regulation of integrin activation
B	0033634	biological_process	positive regulation of cell-cell adhesion mediated by integrin
B	0035754	biological_process	B cell chemotaxis
B	0035768	biological_process	endothelial cell chemotaxis to fibroblast growth factor
B	0042742	biological_process	defense response to bacterium
B	0045236	molecular_function	CXCR chemokine receptor binding
B	0045765	biological_process	regulation of angiogenesis
B	0048018	molecular_function	receptor ligand activity
B	0048248	molecular_function	CXCR3 chemokine receptor binding
B	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
B	0070098	biological_process	chemokine-mediated signaling pathway
B	0071222	biological_process	cellular response to lipopolysaccharide
B	2000545	biological_process	negative regulation of endothelial cell chemotaxis to fibroblast growth factor
C	0002467	biological_process	germinal center formation
C	0002518	biological_process	lymphocyte chemotaxis across high endothelial venule
C	0002544	biological_process	chronic inflammatory response
C	0002920	biological_process	regulation of humoral immune response
C	0005125	molecular_function	cytokine activity
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0006935	biological_process	chemotaxis
C	0006952	biological_process	defense response
C	0006954	biological_process	inflammatory response
C	0006955	biological_process	immune response
C	0007166	biological_process	cell surface receptor signaling pathway
C	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
C	0007267	biological_process	cell-cell signaling
C	0008009	molecular_function	chemokine activity
C	0008201	molecular_function	heparin binding
C	0010820	biological_process	positive regulation of T cell chemotaxis
C	0017134	molecular_function	fibroblast growth factor binding
C	0030593	biological_process	neutrophil chemotaxis
C	0031724	molecular_function	CXCR5 chemokine receptor binding
C	0031735	molecular_function	CCR10 chemokine receptor binding
C	0032487	biological_process	regulation of Rap protein signal transduction
C	0033625	biological_process	positive regulation of integrin activation
C	0033634	biological_process	positive regulation of cell-cell adhesion mediated by integrin
C	0035754	biological_process	B cell chemotaxis
C	0035768	biological_process	endothelial cell chemotaxis to fibroblast growth factor
C	0042742	biological_process	defense response to bacterium
C	0045236	molecular_function	CXCR chemokine receptor binding
C	0045765	biological_process	regulation of angiogenesis
C	0048018	molecular_function	receptor ligand activity
C	0048248	molecular_function	CXCR3 chemokine receptor binding
C	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
C	0070098	biological_process	chemokine-mediated signaling pathway
C	0071222	biological_process	cellular response to lipopolysaccharide
C	2000545	biological_process	negative regulation of endothelial cell chemotaxis to fibroblast growth factor
D	0002467	biological_process	germinal center formation
D	0002518	biological_process	lymphocyte chemotaxis across high endothelial venule
D	0002544	biological_process	chronic inflammatory response
D	0002920	biological_process	regulation of humoral immune response
D	0005125	molecular_function	cytokine activity
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0006935	biological_process	chemotaxis
D	0006952	biological_process	defense response
D	0006954	biological_process	inflammatory response
D	0006955	biological_process	immune response
D	0007166	biological_process	cell surface receptor signaling pathway
D	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
D	0007267	biological_process	cell-cell signaling
D	0008009	molecular_function	chemokine activity
D	0008201	molecular_function	heparin binding
D	0010820	biological_process	positive regulation of T cell chemotaxis
D	0017134	molecular_function	fibroblast growth factor binding
D	0030593	biological_process	neutrophil chemotaxis
D	0031724	molecular_function	CXCR5 chemokine receptor binding
D	0031735	molecular_function	CCR10 chemokine receptor binding
D	0032487	biological_process	regulation of Rap protein signal transduction
D	0033625	biological_process	positive regulation of integrin activation
D	0033634	biological_process	positive regulation of cell-cell adhesion mediated by integrin
D	0035754	biological_process	B cell chemotaxis
D	0035768	biological_process	endothelial cell chemotaxis to fibroblast growth factor
D	0042742	biological_process	defense response to bacterium
D	0045236	molecular_function	CXCR chemokine receptor binding
D	0045765	biological_process	regulation of angiogenesis
D	0048018	molecular_function	receptor ligand activity
D	0048248	molecular_function	CXCR3 chemokine receptor binding
D	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
D	0070098	biological_process	chemokine-mediated signaling pathway
D	0071222	biological_process	cellular response to lipopolysaccharide
D	2000545	biological_process	negative regulation of endothelial cell chemotaxis to fibroblast growth factor
E	0002467	biological_process	germinal center formation
E	0002518	biological_process	lymphocyte chemotaxis across high endothelial venule
E	0002544	biological_process	chronic inflammatory response
E	0002920	biological_process	regulation of humoral immune response
E	0005125	molecular_function	cytokine activity
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0006935	biological_process	chemotaxis
E	0006952	biological_process	defense response
E	0006954	biological_process	inflammatory response
E	0006955	biological_process	immune response
E	0007166	biological_process	cell surface receptor signaling pathway
E	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
E	0007267	biological_process	cell-cell signaling
E	0008009	molecular_function	chemokine activity
E	0008201	molecular_function	heparin binding
E	0010820	biological_process	positive regulation of T cell chemotaxis
E	0017134	molecular_function	fibroblast growth factor binding
E	0030593	biological_process	neutrophil chemotaxis
E	0031724	molecular_function	CXCR5 chemokine receptor binding
E	0031735	molecular_function	CCR10 chemokine receptor binding
E	0032487	biological_process	regulation of Rap protein signal transduction
E	0033625	biological_process	positive regulation of integrin activation
E	0033634	biological_process	positive regulation of cell-cell adhesion mediated by integrin
E	0035754	biological_process	B cell chemotaxis
E	0035768	biological_process	endothelial cell chemotaxis to fibroblast growth factor
E	0042742	biological_process	defense response to bacterium
E	0045236	molecular_function	CXCR chemokine receptor binding
E	0045765	biological_process	regulation of angiogenesis
E	0048018	molecular_function	receptor ligand activity
E	0048248	molecular_function	CXCR3 chemokine receptor binding
E	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
E	0070098	biological_process	chemokine-mediated signaling pathway
E	0071222	biological_process	cellular response to lipopolysaccharide
E	2000545	biological_process	negative regulation of endothelial cell chemotaxis to fibroblast growth factor
F	0002467	biological_process	germinal center formation
F	0002518	biological_process	lymphocyte chemotaxis across high endothelial venule
F	0002544	biological_process	chronic inflammatory response
F	0002920	biological_process	regulation of humoral immune response
F	0005125	molecular_function	cytokine activity
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0006935	biological_process	chemotaxis
F	0006952	biological_process	defense response
F	0006954	biological_process	inflammatory response
F	0006955	biological_process	immune response
F	0007166	biological_process	cell surface receptor signaling pathway
F	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
F	0007267	biological_process	cell-cell signaling
F	0008009	molecular_function	chemokine activity
F	0008201	molecular_function	heparin binding
F	0010820	biological_process	positive regulation of T cell chemotaxis
F	0017134	molecular_function	fibroblast growth factor binding
F	0030593	biological_process	neutrophil chemotaxis
F	0031724	molecular_function	CXCR5 chemokine receptor binding
F	0031735	molecular_function	CCR10 chemokine receptor binding
F	0032487	biological_process	regulation of Rap protein signal transduction
F	0033625	biological_process	positive regulation of integrin activation
F	0033634	biological_process	positive regulation of cell-cell adhesion mediated by integrin
F	0035754	biological_process	B cell chemotaxis
F	0035768	biological_process	endothelial cell chemotaxis to fibroblast growth factor
F	0042742	biological_process	defense response to bacterium
F	0045236	molecular_function	CXCR chemokine receptor binding
F	0045765	biological_process	regulation of angiogenesis
F	0048018	molecular_function	receptor ligand activity
F	0048248	molecular_function	CXCR3 chemokine receptor binding
F	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
F	0070098	biological_process	chemokine-mediated signaling pathway
F	0071222	biological_process	cellular response to lipopolysaccharide
F	2000545	biological_process	negative regulation of endothelial cell chemotaxis to fibroblast growth factor
G	0002467	biological_process	germinal center formation
G	0002518	biological_process	lymphocyte chemotaxis across high endothelial venule
G	0002544	biological_process	chronic inflammatory response
G	0002920	biological_process	regulation of humoral immune response
G	0005125	molecular_function	cytokine activity
G	0005576	cellular_component	extracellular region
G	0005615	cellular_component	extracellular space
G	0006935	biological_process	chemotaxis
G	0006952	biological_process	defense response
G	0006954	biological_process	inflammatory response
G	0006955	biological_process	immune response
G	0007166	biological_process	cell surface receptor signaling pathway
G	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
G	0007267	biological_process	cell-cell signaling
G	0008009	molecular_function	chemokine activity
G	0008201	molecular_function	heparin binding
G	0010820	biological_process	positive regulation of T cell chemotaxis
G	0017134	molecular_function	fibroblast growth factor binding
G	0030593	biological_process	neutrophil chemotaxis
G	0031724	molecular_function	CXCR5 chemokine receptor binding
G	0031735	molecular_function	CCR10 chemokine receptor binding
G	0032487	biological_process	regulation of Rap protein signal transduction
G	0033625	biological_process	positive regulation of integrin activation
G	0033634	biological_process	positive regulation of cell-cell adhesion mediated by integrin
G	0035754	biological_process	B cell chemotaxis
G	0035768	biological_process	endothelial cell chemotaxis to fibroblast growth factor
G	0042742	biological_process	defense response to bacterium
G	0045236	molecular_function	CXCR chemokine receptor binding
G	0045765	biological_process	regulation of angiogenesis
G	0048018	molecular_function	receptor ligand activity
G	0048248	molecular_function	CXCR3 chemokine receptor binding
G	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
G	0070098	biological_process	chemokine-mediated signaling pathway
G	0071222	biological_process	cellular response to lipopolysaccharide
G	2000545	biological_process	negative regulation of endothelial cell chemotaxis to fibroblast growth factor

Functional Information from PROSITE/UniProt

site_id	PS00471
Number of Residues	46
Details	SMALL_CYTOKINES_CXC Small cytokines (intercrine/chemokine) C-x-C subfamily signature. CrCVqessvfIprRfIdrIqilprGngCprkEIIvwkknksiv.CVD

Chain	Residue	Details
A	CYS11-ASP56

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