6VFE
Gasdermin D pore
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 759 |
| Details | Transmembrane: {"description":"Beta stranded","evidences":[{"source":"PubMed","id":"33883744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6VFE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 33 |
| Details | Site: {"description":"Cleavage; by CASP3 or CASP7","evidences":[{"source":"PubMed","id":"28045099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28392147","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37327784","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 33 |
| Details | Site: {"description":"Cleavage; by enterovirus 71 (EV71) Protease 3C and coronavirus SARS-CoV-2 proteinase nsp5","evidences":[{"source":"PubMed","id":"28679757","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35594856","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 66 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 66 |
| Details | Modified residue: {"description":"S-(2-succinyl)cysteine","evidences":[{"source":"PubMed","id":"32820063","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 33 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 33 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"38324683","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38599239","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
