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6VF1

DNA Polymerase Mu, 8-oxorGTP:At Product State Ternary Complex, 50 mM Mg2+ (120 min)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0005634cellular_componentnucleus
A0006281biological_processDNA repair
A0016779molecular_functionnucleotidyltransferase activity
A0034061molecular_functionDNA polymerase activity
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue MG A 501
ChainResidue
AASP330
AASP332
AMG502
AGOA506
AHOH606
AHOH626
P8GM5

site_idAC2
Number of Residues7
Detailsbinding site for residue MG A 502
ChainResidue
AASP418
AMG501
AHOH602
PDA4
P8GM5
AASP330
AASP332

site_idAC3
Number of Residues6
Detailsbinding site for residue NA A 503
ChainResidue
ATHR241
AILE243
AVAL246
AHOH822
PDT3
PHOH115

site_idAC4
Number of Residues4
Detailsbinding site for residue CL A 504
ChainResidue
ASER172
AGLY174
AARG175
AHOH782

site_idAC5
Number of Residues2
Detailsbinding site for residue DTT A 505
ChainResidue
ACYS180
AHOH855

site_idAC6
Number of Residues9
Detailsbinding site for residue GOA A 506
ChainResidue
AGLY320
AARG323
ALYS325
AASP332
AMG501
AHOH606
AHOH779
AHOH816
P8GM5

site_idAC7
Number of Residues4
Detailsbinding site for residue EPE A 507
ChainResidue
ALYS325
ALEU326
AGLN327
AHOH668

site_idAC8
Number of Residues5
Detailsbinding site for residue EDO A 508
ChainResidue
AARG387
ATRP434
AARG445
PDA4
P8GM5

site_idAC9
Number of Residues4
Detailsbinding site for residue NA T 101
ChainResidue
THOH205
THOH206
THOH213
THOH237

Functional Information from PROSITE/UniProt
site_idPS00522
Number of Residues20
DetailsDNA_POLYMERASE_X DNA polymerase family X signature. GGFrRGklqGhDVDFLIthP
ChainResidueDetails
AGLY319-PRO338

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP330
AASP332
AALA430

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Responsible for the low discrimination between dNTP and rNTP
ChainResidueDetails
AARG445

226707

PDB entries from 2024-10-30

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