Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6VE7

The inner junction complex of Chlamydomonas reinhardtii doublet microtubule

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0005200	molecular_function	structural constituent of cytoskeleton
0	0005525	molecular_function	GTP binding
0	0005856	cellular_component	cytoskeleton
0	0005874	cellular_component	microtubule
0	0007010	biological_process	cytoskeleton organization
0	0007017	biological_process	microtubule-based process
1	0005200	molecular_function	structural constituent of cytoskeleton
1	0005525	molecular_function	GTP binding
1	0005856	cellular_component	cytoskeleton
1	0005874	cellular_component	microtubule
1	0007010	biological_process	cytoskeleton organization
1	0007017	biological_process	microtubule-based process
2	0030544	molecular_function	Hsp70 protein binding
2	0051879	molecular_function	Hsp90 protein binding
3	0005875	cellular_component	microtubule associated complex
3	0005879	cellular_component	axonemal microtubule
3	0031514	cellular_component	motile cilium
3	0035082	biological_process	axoneme assembly
3	0036064	cellular_component	ciliary basal body
3	0045724	biological_process	positive regulation of cilium assembly
3	0060271	biological_process	cilium assembly
3	0060296	biological_process	regulation of cilium beat frequency involved in ciliary motility
3	0072594	biological_process	establishment of protein localization to organelle
3	0097540	cellular_component	axonemal central pair
3	0097545	cellular_component	axonemal doublet microtubule
3	2000155	biological_process	positive regulation of cilium-dependent cell motility
4	0003924	molecular_function	GTPase activity
4	0005200	molecular_function	structural constituent of cytoskeleton
4	0005525	molecular_function	GTP binding
4	0005856	cellular_component	cytoskeleton
4	0005874	cellular_component	microtubule
4	0007010	biological_process	cytoskeleton organization
4	0007017	biological_process	microtubule-based process
5	0005200	molecular_function	structural constituent of cytoskeleton
5	0005525	molecular_function	GTP binding
5	0005856	cellular_component	cytoskeleton
5	0005874	cellular_component	microtubule
5	0007010	biological_process	cytoskeleton organization
5	0007017	biological_process	microtubule-based process
6	0005200	molecular_function	structural constituent of cytoskeleton
6	0005525	molecular_function	GTP binding
6	0005856	cellular_component	cytoskeleton
6	0005874	cellular_component	microtubule
6	0007010	biological_process	cytoskeleton organization
6	0007017	biological_process	microtubule-based process
7	0005200	molecular_function	structural constituent of cytoskeleton
7	0005525	molecular_function	GTP binding
7	0005856	cellular_component	cytoskeleton
7	0005874	cellular_component	microtubule
7	0007010	biological_process	cytoskeleton organization
7	0007017	biological_process	microtubule-based process
8	0003924	molecular_function	GTPase activity
8	0005200	molecular_function	structural constituent of cytoskeleton
8	0005525	molecular_function	GTP binding
8	0005856	cellular_component	cytoskeleton
8	0005874	cellular_component	microtubule
8	0007010	biological_process	cytoskeleton organization
8	0007017	biological_process	microtubule-based process
9	0003924	molecular_function	GTPase activity
9	0005200	molecular_function	structural constituent of cytoskeleton
9	0005525	molecular_function	GTP binding
9	0005856	cellular_component	cytoskeleton
9	0005874	cellular_component	microtubule
9	0007010	biological_process	cytoskeleton organization
9	0007017	biological_process	microtubule-based process
a	0003924	molecular_function	GTPase activity
a	0005200	molecular_function	structural constituent of cytoskeleton
a	0005525	molecular_function	GTP binding
a	0005856	cellular_component	cytoskeleton
a	0005874	cellular_component	microtubule
a	0007010	biological_process	cytoskeleton organization
a	0007017	biological_process	microtubule-based process
A	0005516	molecular_function	calmodulin binding
A	0005856	cellular_component	cytoskeleton
A	0005929	cellular_component	cilium
A	0120025	cellular_component	plasma membrane bounded cell projection
b	0003924	molecular_function	GTPase activity
b	0005200	molecular_function	structural constituent of cytoskeleton
b	0005525	molecular_function	GTP binding
b	0005856	cellular_component	cytoskeleton
b	0005874	cellular_component	microtubule
b	0007010	biological_process	cytoskeleton organization
b	0007017	biological_process	microtubule-based process
B	0005737	cellular_component	cytoplasm
B	0005930	cellular_component	axoneme
B	0031514	cellular_component	motile cilium
c	0005875	cellular_component	microtubule associated complex
c	0005879	cellular_component	axonemal microtubule
c	0031514	cellular_component	motile cilium
c	0035082	biological_process	axoneme assembly
c	0036064	cellular_component	ciliary basal body
c	0045724	biological_process	positive regulation of cilium assembly
c	0060271	biological_process	cilium assembly
c	0060296	biological_process	regulation of cilium beat frequency involved in ciliary motility
c	0072594	biological_process	establishment of protein localization to organelle
c	0097540	cellular_component	axonemal central pair
c	0097545	cellular_component	axonemal doublet microtubule
c	2000155	biological_process	positive regulation of cilium-dependent cell motility
C	0005737	cellular_component	cytoplasm
C	0005930	cellular_component	axoneme
C	0031514	cellular_component	motile cilium
d	0030544	molecular_function	Hsp70 protein binding
d	0051879	molecular_function	Hsp90 protein binding
D	0005200	molecular_function	structural constituent of cytoskeleton
D	0005525	molecular_function	GTP binding
D	0005856	cellular_component	cytoskeleton
D	0005874	cellular_component	microtubule
D	0007010	biological_process	cytoskeleton organization
D	0007017	biological_process	microtubule-based process
e	0005200	molecular_function	structural constituent of cytoskeleton
e	0005525	molecular_function	GTP binding
e	0005856	cellular_component	cytoskeleton
e	0005874	cellular_component	microtubule
e	0007010	biological_process	cytoskeleton organization
e	0007017	biological_process	microtubule-based process
E	0005200	molecular_function	structural constituent of cytoskeleton
E	0005525	molecular_function	GTP binding
E	0005856	cellular_component	cytoskeleton
E	0005874	cellular_component	microtubule
E	0007010	biological_process	cytoskeleton organization
E	0007017	biological_process	microtubule-based process
f	0005200	molecular_function	structural constituent of cytoskeleton
f	0005525	molecular_function	GTP binding
f	0005856	cellular_component	cytoskeleton
f	0005874	cellular_component	microtubule
f	0007010	biological_process	cytoskeleton organization
f	0007017	biological_process	microtubule-based process
F	0005200	molecular_function	structural constituent of cytoskeleton
F	0005525	molecular_function	GTP binding
F	0005856	cellular_component	cytoskeleton
F	0005874	cellular_component	microtubule
F	0007010	biological_process	cytoskeleton organization
F	0007017	biological_process	microtubule-based process
g	0005875	cellular_component	microtubule associated complex
g	0005879	cellular_component	axonemal microtubule
g	0031514	cellular_component	motile cilium
g	0035082	biological_process	axoneme assembly
g	0036064	cellular_component	ciliary basal body
g	0045724	biological_process	positive regulation of cilium assembly
g	0060271	biological_process	cilium assembly
g	0060296	biological_process	regulation of cilium beat frequency involved in ciliary motility
g	0072594	biological_process	establishment of protein localization to organelle
g	0097540	cellular_component	axonemal central pair
g	0097545	cellular_component	axonemal doublet microtubule
g	2000155	biological_process	positive regulation of cilium-dependent cell motility
G	0005200	molecular_function	structural constituent of cytoskeleton
G	0005525	molecular_function	GTP binding
G	0005856	cellular_component	cytoskeleton
G	0005874	cellular_component	microtubule
G	0007010	biological_process	cytoskeleton organization
G	0007017	biological_process	microtubule-based process
h	0005200	molecular_function	structural constituent of cytoskeleton
h	0005525	molecular_function	GTP binding
h	0005856	cellular_component	cytoskeleton
h	0005874	cellular_component	microtubule
h	0007010	biological_process	cytoskeleton organization
h	0007017	biological_process	microtubule-based process
i	0003924	molecular_function	GTPase activity
i	0005200	molecular_function	structural constituent of cytoskeleton
i	0005525	molecular_function	GTP binding
i	0005856	cellular_component	cytoskeleton
i	0005874	cellular_component	microtubule
i	0007010	biological_process	cytoskeleton organization
i	0007017	biological_process	microtubule-based process
I	0003924	molecular_function	GTPase activity
I	0005200	molecular_function	structural constituent of cytoskeleton
I	0005525	molecular_function	GTP binding
I	0005856	cellular_component	cytoskeleton
I	0005874	cellular_component	microtubule
I	0007010	biological_process	cytoskeleton organization
I	0007017	biological_process	microtubule-based process
j	0003924	molecular_function	GTPase activity
j	0005200	molecular_function	structural constituent of cytoskeleton
j	0005525	molecular_function	GTP binding
j	0005856	cellular_component	cytoskeleton
j	0005874	cellular_component	microtubule
j	0007010	biological_process	cytoskeleton organization
j	0007017	biological_process	microtubule-based process
J	0003924	molecular_function	GTPase activity
J	0005200	molecular_function	structural constituent of cytoskeleton
J	0005525	molecular_function	GTP binding
J	0005856	cellular_component	cytoskeleton
J	0005874	cellular_component	microtubule
J	0007010	biological_process	cytoskeleton organization
J	0007017	biological_process	microtubule-based process
k	0005200	molecular_function	structural constituent of cytoskeleton
k	0005525	molecular_function	GTP binding
k	0005856	cellular_component	cytoskeleton
k	0005874	cellular_component	microtubule
k	0007010	biological_process	cytoskeleton organization
k	0007017	biological_process	microtubule-based process
K	0003924	molecular_function	GTPase activity
K	0005200	molecular_function	structural constituent of cytoskeleton
K	0005525	molecular_function	GTP binding
K	0005856	cellular_component	cytoskeleton
K	0005874	cellular_component	microtubule
K	0007010	biological_process	cytoskeleton organization
K	0007017	biological_process	microtubule-based process
l	0030544	molecular_function	Hsp70 protein binding
l	0051879	molecular_function	Hsp90 protein binding
L	0005200	molecular_function	structural constituent of cytoskeleton
L	0005525	molecular_function	GTP binding
L	0005856	cellular_component	cytoskeleton
L	0005874	cellular_component	microtubule
L	0007010	biological_process	cytoskeleton organization
L	0007017	biological_process	microtubule-based process
m	0005200	molecular_function	structural constituent of cytoskeleton
m	0005525	molecular_function	GTP binding
m	0005856	cellular_component	cytoskeleton
m	0005874	cellular_component	microtubule
m	0007010	biological_process	cytoskeleton organization
m	0007017	biological_process	microtubule-based process
M	0005200	molecular_function	structural constituent of cytoskeleton
M	0005525	molecular_function	GTP binding
M	0005856	cellular_component	cytoskeleton
M	0005874	cellular_component	microtubule
M	0007010	biological_process	cytoskeleton organization
M	0007017	biological_process	microtubule-based process
n	0030544	molecular_function	Hsp70 protein binding
n	0051879	molecular_function	Hsp90 protein binding
N	0003924	molecular_function	GTPase activity
N	0005200	molecular_function	structural constituent of cytoskeleton
N	0005525	molecular_function	GTP binding
N	0005856	cellular_component	cytoskeleton
N	0005874	cellular_component	microtubule
N	0007010	biological_process	cytoskeleton organization
N	0007017	biological_process	microtubule-based process
o	0005200	molecular_function	structural constituent of cytoskeleton
o	0005525	molecular_function	GTP binding
o	0005856	cellular_component	cytoskeleton
o	0005874	cellular_component	microtubule
o	0007010	biological_process	cytoskeleton organization
o	0007017	biological_process	microtubule-based process
O	0003924	molecular_function	GTPase activity
O	0005200	molecular_function	structural constituent of cytoskeleton
O	0005525	molecular_function	GTP binding
O	0005856	cellular_component	cytoskeleton
O	0005874	cellular_component	microtubule
O	0007010	biological_process	cytoskeleton organization
O	0007017	biological_process	microtubule-based process
p	0003924	molecular_function	GTPase activity
p	0005200	molecular_function	structural constituent of cytoskeleton
p	0005525	molecular_function	GTP binding
p	0005856	cellular_component	cytoskeleton
p	0005874	cellular_component	microtubule
p	0007010	biological_process	cytoskeleton organization
p	0007017	biological_process	microtubule-based process
P	0005200	molecular_function	structural constituent of cytoskeleton
P	0005525	molecular_function	GTP binding
P	0005856	cellular_component	cytoskeleton
P	0005874	cellular_component	microtubule
P	0007010	biological_process	cytoskeleton organization
P	0007017	biological_process	microtubule-based process
q	0003924	molecular_function	GTPase activity
q	0005200	molecular_function	structural constituent of cytoskeleton
q	0005525	molecular_function	GTP binding
q	0005856	cellular_component	cytoskeleton
q	0005874	cellular_component	microtubule
q	0007010	biological_process	cytoskeleton organization
q	0007017	biological_process	microtubule-based process
Q	0003924	molecular_function	GTPase activity
Q	0005200	molecular_function	structural constituent of cytoskeleton
Q	0005525	molecular_function	GTP binding
Q	0005856	cellular_component	cytoskeleton
Q	0005874	cellular_component	microtubule
Q	0007010	biological_process	cytoskeleton organization
Q	0007017	biological_process	microtubule-based process
r	0003924	molecular_function	GTPase activity
r	0005200	molecular_function	structural constituent of cytoskeleton
r	0005525	molecular_function	GTP binding
r	0005856	cellular_component	cytoskeleton
r	0005874	cellular_component	microtubule
r	0007010	biological_process	cytoskeleton organization
r	0007017	biological_process	microtubule-based process
R	0003924	molecular_function	GTPase activity
R	0005200	molecular_function	structural constituent of cytoskeleton
R	0005525	molecular_function	GTP binding
R	0005856	cellular_component	cytoskeleton
R	0005874	cellular_component	microtubule
R	0007010	biological_process	cytoskeleton organization
R	0007017	biological_process	microtubule-based process
s	0005200	molecular_function	structural constituent of cytoskeleton
s	0005525	molecular_function	GTP binding
s	0005856	cellular_component	cytoskeleton
s	0005874	cellular_component	microtubule
s	0007010	biological_process	cytoskeleton organization
s	0007017	biological_process	microtubule-based process
S	0005200	molecular_function	structural constituent of cytoskeleton
S	0005525	molecular_function	GTP binding
S	0005856	cellular_component	cytoskeleton
S	0005874	cellular_component	microtubule
S	0007010	biological_process	cytoskeleton organization
S	0007017	biological_process	microtubule-based process
t	0003924	molecular_function	GTPase activity
t	0005200	molecular_function	structural constituent of cytoskeleton
t	0005525	molecular_function	GTP binding
t	0005856	cellular_component	cytoskeleton
t	0005874	cellular_component	microtubule
t	0007010	biological_process	cytoskeleton organization
t	0007017	biological_process	microtubule-based process
T	0003924	molecular_function	GTPase activity
T	0005200	molecular_function	structural constituent of cytoskeleton
T	0005525	molecular_function	GTP binding
T	0005856	cellular_component	cytoskeleton
T	0005874	cellular_component	microtubule
T	0007010	biological_process	cytoskeleton organization
T	0007017	biological_process	microtubule-based process
u	0003924	molecular_function	GTPase activity
u	0005200	molecular_function	structural constituent of cytoskeleton
u	0005525	molecular_function	GTP binding
u	0005856	cellular_component	cytoskeleton
u	0005874	cellular_component	microtubule
u	0007010	biological_process	cytoskeleton organization
u	0007017	biological_process	microtubule-based process
U	0003924	molecular_function	GTPase activity
U	0005200	molecular_function	structural constituent of cytoskeleton
U	0005525	molecular_function	GTP binding
U	0005856	cellular_component	cytoskeleton
U	0005874	cellular_component	microtubule
U	0007010	biological_process	cytoskeleton organization
U	0007017	biological_process	microtubule-based process
v	0003924	molecular_function	GTPase activity
v	0005200	molecular_function	structural constituent of cytoskeleton
v	0005525	molecular_function	GTP binding
v	0005856	cellular_component	cytoskeleton
v	0005874	cellular_component	microtubule
v	0007010	biological_process	cytoskeleton organization
v	0007017	biological_process	microtubule-based process
V	0003924	molecular_function	GTPase activity
V	0005200	molecular_function	structural constituent of cytoskeleton
V	0005525	molecular_function	GTP binding
V	0005856	cellular_component	cytoskeleton
V	0005874	cellular_component	microtubule
V	0007010	biological_process	cytoskeleton organization
V	0007017	biological_process	microtubule-based process
w	0003924	molecular_function	GTPase activity
w	0005200	molecular_function	structural constituent of cytoskeleton
w	0005525	molecular_function	GTP binding
w	0005856	cellular_component	cytoskeleton
w	0005874	cellular_component	microtubule
w	0007010	biological_process	cytoskeleton organization
w	0007017	biological_process	microtubule-based process
X	0005200	molecular_function	structural constituent of cytoskeleton
X	0005525	molecular_function	GTP binding
X	0005856	cellular_component	cytoskeleton
X	0005874	cellular_component	microtubule
X	0007010	biological_process	cytoskeleton organization
X	0007017	biological_process	microtubule-based process
y	0005200	molecular_function	structural constituent of cytoskeleton
y	0005525	molecular_function	GTP binding
y	0005856	cellular_component	cytoskeleton
y	0005874	cellular_component	microtubule
y	0007010	biological_process	cytoskeleton organization
y	0007017	biological_process	microtubule-based process
Y	0005200	molecular_function	structural constituent of cytoskeleton
Y	0005525	molecular_function	GTP binding
Y	0005856	cellular_component	cytoskeleton
Y	0005874	cellular_component	microtubule
Y	0007010	biological_process	cytoskeleton organization
Y	0007017	biological_process	microtubule-based process
z	0005875	cellular_component	microtubule associated complex
z	0005879	cellular_component	axonemal microtubule
z	0031514	cellular_component	motile cilium
z	0035082	biological_process	axoneme assembly
z	0036064	cellular_component	ciliary basal body
z	0045724	biological_process	positive regulation of cilium assembly
z	0060271	biological_process	cilium assembly
z	0060296	biological_process	regulation of cilium beat frequency involved in ciliary motility
z	0072594	biological_process	establishment of protein localization to organelle
z	0097540	cellular_component	axonemal central pair
z	0097545	cellular_component	axonemal doublet microtubule
z	2000155	biological_process	positive regulation of cilium-dependent cell motility
Z	0005200	molecular_function	structural constituent of cytoskeleton
Z	0005525	molecular_function	GTP binding
Z	0005856	cellular_component	cytoskeleton
Z	0005874	cellular_component	microtubule
Z	0007010	biological_process	cytoskeleton organization
Z	0007017	biological_process	microtubule-based process

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue GTP D 501

Chain	Residue
D	GLN11
D	THR145
D	GLY146
D	THR179
D	GLU183
D	ASN206
D	TYR224
D	ASN228
D	MG502
R	LYS252
D	ALA12
D	GLN15
D	GLU71
D	ALA99
D	ALA100
D	ASN101
D	GLY143
D	GLY144

site_id	AC2
Number of Residues	2
Details	binding site for residue MG D 502

Chain	Residue
D	GLU71
D	GTP501

site_id	AC3
Number of Residues	18
Details	binding site for residue GTP E 501

Chain	Residue
E	GLN11
E	ALA12
E	GLN15
E	GLU71
E	ASP98
E	ALA99
E	ALA100
E	ASN101
E	ALA140
E	GLY143
E	GLY144
E	THR145
E	GLY146
E	ASN206
E	TYR224
E	ASN228
E	MG502
I	LYS252

site_id	AC4
Number of Residues	2
Details	binding site for residue MG E 502

Chain	Residue
E	GTP501
I	LYS252

site_id	AC5
Number of Residues	18
Details	binding site for residue GTP F 501

Chain	Residue
F	GLN11
F	ALA12
F	GLN15
F	GLU71
F	ALA99
F	ALA100
F	ASN101
F	GLY143
F	GLY144
F	THR145
F	GLY146
F	THR179
F	ASN206
F	TYR224
F	LEU227
F	ASN228
F	MG502
J	LYS252

site_id	AC6
Number of Residues	2
Details	binding site for residue MG F 502

Chain	Residue
F	GLU71
F	GTP501

site_id	AC7
Number of Residues	19
Details	binding site for residue GTP G 501

Chain	Residue
9	LYS252
G	GLY10
G	GLN11
G	ALA12
G	GLN15
G	GLU71
G	ALA99
G	ALA100
G	ASN101
G	GLY143
G	GLY144
G	THR145
G	GLY146
G	THR179
G	ASN206
G	TYR224
G	LEU227
G	ASN228
G	MG502

site_id	AC8
Number of Residues	2
Details	binding site for residue MG G 502

Chain	Residue
G	GLU71
G	GTP501

site_id	AC9
Number of Residues	12
Details	binding site for residue GDP I 501

Chain	Residue
I	GLN11
I	CYS12
I	GLN15
I	ASN99
I	GLY141
I	GLY142
I	THR143
I	GLY144
I	ASP177
I	ASN204
I	PHE222
I	ASN226

site_id	AD1
Number of Residues	13
Details	binding site for residue GDP J 501

Chain	Residue
J	THR143
J	GLY144
J	ASP177
J	ASN204
J	PHE222
J	LEU225
J	ASN226
J	GLN11
J	CYS12
J	GLN15
J	SER138
J	GLY141
J	GLY142

site_id	AD2
Number of Residues	13
Details	binding site for residue TA1 J 502

Chain	Residue
J	VAL23
J	ASP26
J	GLU27
J	LEU215
J	HIS227
J	SER234
J	LEU273
J	THR274
J	ARG276
J	GLN279
J	LYS359
J	GLY360
J	LEU361

site_id	AD3
Number of Residues	14
Details	binding site for residue GDP K 501

Chain	Residue
K	GLN11
K	CYS12
K	GLN15
K	ASN99
K	SER138
K	GLY141
K	GLY142
K	THR143
K	GLY144
K	ASP177
K	ASN204
K	PHE222
K	ASN226
S	LEU248

site_id	AD4
Number of Residues	17
Details	binding site for residue GTP L 501

Chain	Residue
K	LYS252
L	GLY10
L	GLN11
L	ALA12
L	GLN15
L	GLU71
L	ALA99
L	ALA100
L	ASN101
L	GLY143
L	GLY144
L	THR145
L	GLY146
L	ASN206
L	TYR224
L	ASN228
L	MG502

site_id	AD5
Number of Residues	3
Details	binding site for residue MG L 502

Chain	Residue
K	LYS252
L	GLU71
L	GTP501

site_id	AD6
Number of Residues	16
Details	binding site for residue GTP M 501

Chain	Residue
M	GLY10
M	GLN11
M	ALA12
M	GLN15
M	GLU71
M	ALA100
M	ASN101
M	GLY143
M	GLY144
M	THR145
M	GLY146
M	ASN206
M	TYR224
M	ASN228
M	MG502
T	LYS252

site_id	AD7
Number of Residues	2
Details	binding site for residue MG M 502

Chain	Residue
M	GLU71
M	GTP501

site_id	AD8
Number of Residues	12
Details	binding site for residue GDP N 501

Chain	Residue
N	GLN11
N	CYS12
N	GLN15
N	ASN99
N	SER138
N	GLY141
N	GLY142
N	THR143
N	GLY144
N	ASP177
N	PHE222
N	ASN226

site_id	AD9
Number of Residues	13
Details	binding site for residue GDP O 501

Chain	Residue
O	GLY10
O	GLN11
O	CYS12
O	GLN15
O	SER138
O	GLY141
O	GLY142
O	THR143
O	GLY144
O	ASP177
O	ASN204
O	PHE222
O	ASN226

site_id	AE1
Number of Residues	18
Details	binding site for residue GTP P 501

Chain	Residue
O	LYS252
P	GLY10
P	GLN11
P	ALA12
P	GLN15
P	GLU71
P	ALA99
P	ALA100
P	ASN101
P	GLY143
P	GLY144
P	THR145
P	GLY146
P	THR179
P	ASN206
P	TYR224
P	ASN228
P	MG502

site_id	AE2
Number of Residues	2
Details	binding site for residue MG P 502

Chain	Residue
P	GLU71
P	GTP501

site_id	AE3
Number of Residues	12
Details	binding site for residue GDP Q 501

Chain	Residue
Q	GLY10
Q	GLN11
Q	CYS12
Q	GLN15
Q	ASP67
Q	GLY141
Q	GLY142
Q	THR143
Q	GLY144
Q	ASP177
Q	PHE222
Q	ASN226

site_id	AE4
Number of Residues	13
Details	binding site for residue GDP R 501

Chain	Residue
R	GLY10
R	GLN11
R	CYS12
R	GLN15
R	SER138
R	GLY141
R	GLY142
R	THR143
R	GLY144
R	ASP177
R	ASN204
R	PHE222
R	ASN226

site_id	AE5
Number of Residues	15
Details	binding site for residue GTP S 501

Chain	Residue
Q	LYS252
S	GLY10
S	GLN11
S	ALA12
S	GLN15
S	ALA100
S	ASN101
S	GLY143
S	GLY144
S	THR145
S	GLY146
S	ASN206
S	TYR224
S	ASN228
S	MG502

site_id	AE6
Number of Residues	2
Details	binding site for residue MG S 502

Chain	Residue
Q	LYS252
S	GTP501

site_id	AE7
Number of Residues	13
Details	binding site for residue GDP T 501

Chain	Residue
T	GLN11
T	CYS12
T	GLN15
T	ASN99
T	SER138
T	GLY141
T	GLY142
T	THR143
T	GLY144
T	ASP177
T	ASN204
T	PHE222
T	ASN226

site_id	AE8
Number of Residues	12
Details	binding site for residue GDP U 501

Chain	Residue
U	GLN11
U	CYS12
U	GLN15
U	ASN99
U	SER138
U	GLY141
U	GLY142
U	THR143
U	GLY144
U	ASP177
U	PHE222
U	ASN226

site_id	AE9
Number of Residues	13
Details	binding site for residue GDP V 501

Chain	Residue
V	GLN11
V	CYS12
V	GLN15
V	ILE16
V	ASN99
V	SER138
V	GLY141
V	GLY142
V	THR143
V	GLY144
V	ASP177
V	PHE222
V	ASN226

site_id	AF1
Number of Residues	14
Details	binding site for residue TA1 V 502

Chain	Residue
V	VAL23
V	ASP26
V	GLU27
V	LEU215
V	HIS227
V	LEU228
V	ALA231
V	SER234
V	THR274
V	GLN279
V	PRO358
V	LYS359
V	GLY360
V	LEU361

site_id	AF2
Number of Residues	18
Details	binding site for residue GTP X 501

Chain	Residue
X	GLY10
X	GLN11
X	ALA12
X	GLN15
X	GLU71
X	ALA99
X	ALA100
X	ASN101
X	GLY143
X	GLY144
X	THR145
X	GLY146
X	THR179
X	ASN206
X	TYR224
X	ASN228
X	MG502
i	LYS252

site_id	AF3
Number of Residues	2
Details	binding site for residue MG X 502

Chain	Residue
X	GLU71
X	GTP501

site_id	AF4
Number of Residues	19
Details	binding site for residue GTP Y 501

Chain	Residue
Y	GLY10
Y	GLN11
Y	ALA12
Y	GLN15
Y	GLU71
Y	ALA99
Y	ALA100
Y	ASN101
Y	GLY143
Y	GLY144
Y	THR145
Y	GLY146
Y	THR179
Y	ASN206
Y	TYR224
Y	LEU227
Y	ASN228
Y	MG502
b	LYS252

site_id	AF5
Number of Residues	2
Details	binding site for residue MG Y 502

Chain	Residue
Y	GLU71
Y	GTP501

site_id	AF6
Number of Residues	19
Details	binding site for residue GTP Z 501

Chain	Residue
Z	GLY10
Z	GLN11
Z	ALA12
Z	GLN15
Z	GLU71
Z	ALA99
Z	ALA100
Z	ASN101
Z	GLY143
Z	GLY144
Z	THR145
Z	GLY146
Z	THR179
Z	ASN206
Z	TYR224
Z	LEU227
Z	ASN228
Z	MG502
j	LYS252

site_id	AF7
Number of Residues	2
Details	binding site for residue MG Z 502

Chain	Residue
Z	GLU71
Z	GTP501

site_id	AF8
Number of Residues	12
Details	binding site for residue GDP a 501

Chain	Residue
a	GLN11
a	CYS12
a	GLN15
a	ASN99
a	SER138
a	GLY141
a	GLY142
a	THR143
a	GLY144
a	ASP177
a	PHE222
a	ASN226

site_id	AF9
Number of Residues	14
Details	binding site for residue TA1 a 502

Chain	Residue
a	VAL23
a	ASP26
a	GLU27
a	LEU215
a	HIS227
a	SER234
a	LEU273
a	THR274
a	ARG276
a	GLN279
a	PRO358
a	LYS359
a	GLY360
a	LEU361

site_id	AG1
Number of Residues	12
Details	binding site for residue GDP b 501

Chain	Residue
b	GLN11
b	CYS12
b	GLN15
b	ALA97
b	ASN99
b	GLY141
b	GLY142
b	THR143
b	GLY144
b	ASP177
b	PHE222
b	ASN226

site_id	AG2
Number of Residues	12
Details	binding site for residue TA1 b 502

Chain	Residue
b	VAL23
b	LEU215
b	HIS227
b	LEU228
b	SER234
b	LEU273
b	THR274
b	ARG276
b	PRO358
b	LYS359
b	GLY360
b	LEU361

site_id	AG3
Number of Residues	18
Details	binding site for residue GTP e 501

Chain	Residue
V	LYS252
e	GLY10
e	GLN11
e	ALA12
e	GLN15
e	GLU71
e	ASP98
e	ALA100
e	ASN101
e	GLY143
e	GLY144
e	THR145
e	GLY146
e	THR179
e	TYR224
e	LEU227
e	ASN228
e	MG502

site_id	AG4
Number of Residues	3
Details	binding site for residue MG e 502

Chain	Residue
V	LYS252
e	GLU71
e	GTP501

site_id	AG5
Number of Residues	18
Details	binding site for residue GTP f 501

Chain	Residue
N	LYS252
f	GLY10
f	GLN11
f	ALA12
f	GLN15
f	GLU71
f	ALA99
f	ALA100
f	ASN101
f	GLY143
f	GLY144
f	THR145
f	GLY146
f	THR179
f	ASN206
f	TYR224
f	ASN228
f	MG502

site_id	AG6
Number of Residues	1
Details	binding site for residue MG f 502

Chain	Residue
f	GTP501

site_id	AG7
Number of Residues	19
Details	binding site for residue GTP h 501

Chain	Residue
8	LYS252
h	GLY10
h	GLN11
h	ALA12
h	GLN15
h	GLU71
h	ALA99
h	ALA100
h	ASN101
h	GLY143
h	GLY144
h	THR145
h	GLY146
h	THR179
h	ASN206
h	TYR224
h	LEU227
h	ASN228
h	MG502

site_id	AG8
Number of Residues	3
Details	binding site for residue MG h 502

Chain	Residue
8	LYS252
h	GLU71
h	GTP501

site_id	AG9
Number of Residues	12
Details	binding site for residue GDP i 501

Chain	Residue
i	GLN11
i	CYS12
i	GLN15
i	ALA97
i	ASN99
i	GLY141
i	GLY142
i	THR143
i	GLY144
i	ASP177
i	PHE222
i	ASN226

site_id	AH1
Number of Residues	13
Details	binding site for residue TA1 i 502

Chain	Residue
i	VAL23
i	ASP26
i	GLU27
i	LEU215
i	HIS227
i	LEU228
i	SER234
i	THR274
i	GLN279
i	PRO358
i	LYS359
i	GLY360
i	LEU361

site_id	AH2
Number of Residues	12
Details	binding site for residue GDP j 501

Chain	Residue
j	GLN11
j	CYS12
j	GLN15
j	ALA97
j	SER138
j	GLY141
j	GLY142
j	THR143
j	GLY144
j	ASP177
j	PHE222
j	ASN226

site_id	AH3
Number of Residues	15
Details	binding site for residue TA1 j 502

Chain	Residue
j	VAL23
j	ASP26
j	GLU27
j	HIS227
j	LEU228
j	SER234
j	PHE270
j	LEU273
j	THR274
j	ARG276
j	GLN279
j	PRO358
j	LYS359
j	GLY360
j	LEU361

site_id	AH4
Number of Residues	17
Details	binding site for residue GTP k 501

Chain	Residue
U	LYS252
k	GLY10
k	GLN11
k	ALA12
k	GLN15
k	GLU71
k	ALA99
k	ALA100
k	ASN101
k	GLY143
k	GLY144
k	THR145
k	GLY146
k	THR179
k	ASN206
k	ASN228
k	MG502

site_id	AH5
Number of Residues	2
Details	binding site for residue MG k 502

Chain	Residue
k	GLU71
k	GTP501

site_id	AH6
Number of Residues	19
Details	binding site for residue GTP m 501

Chain	Residue
m	GLY10
m	GLN11
m	ALA12
m	GLN15
m	GLU71
m	ASP98
m	ALA99
m	ALA100
m	ASN101
m	GLY143
m	GLY144
m	THR145
m	GLY146
m	THR179
m	ASN206
m	TYR224
m	ASN228
m	MG502
q	LYS252

site_id	AH7
Number of Residues	2
Details	binding site for residue MG m 502

Chain	Residue
m	GLU71
m	GTP501

site_id	AH8
Number of Residues	19
Details	binding site for residue GTP o 501

Chain	Residue
o	GLY10
o	GLN11
o	ALA12
o	GLN15
o	GLU71
o	ASP98
o	ALA99
o	ALA100
o	ASN101
o	GLY143
o	GLY144
o	THR145
o	GLY146
o	THR179
o	ASN206
o	TYR224
o	ASN228
o	MG502
t	LYS252

site_id	AH9
Number of Residues	3
Details	binding site for residue MG o 502

Chain	Residue
o	GLU71
o	GTP501
t	LYS252

site_id	AI1
Number of Residues	13
Details	binding site for residue GDP p 501

Chain	Residue
p	GLN11
p	CYS12
p	GLN15
p	ASN99
p	SER138
p	GLY141
p	GLY142
p	THR143
p	GLY144
p	ASP177
p	ASN204
p	PHE222
p	ASN226

site_id	AI2
Number of Residues	14
Details	binding site for residue TA1 p 502

Chain	Residue
p	GLU22
p	VAL23
p	ASP26
p	LEU215
p	HIS227
p	LEU228
p	SER234
p	PRO272
p	THR274
p	ARG276
p	GLN279
p	LYS359
p	GLY360
p	LEU361

site_id	AI3
Number of Residues	3
Details	binding site for residue MG p 503

Chain	Residue
p	LYS252
y	GLU71
y	GTP501

site_id	AI4
Number of Residues	14
Details	binding site for residue GDP q 501

Chain	Residue
q	GLN11
q	CYS12
q	GLN15
q	ASN99
q	SER138
q	GLY141
q	GLY142
q	THR143
q	GLY144
q	ASP177
q	ASN204
q	PHE222
q	LEU225
q	ASN226

site_id	AI5
Number of Residues	13
Details	binding site for residue TA1 q 502

Chain	Residue
q	VAL23
q	ASP26
q	LEU215
q	HIS227
q	LEU228
q	SER234
q	PRO272
q	THR274
q	ARG276
q	GLN279
q	LYS359
q	GLY360
q	LEU361

site_id	AI6
Number of Residues	13
Details	binding site for residue GDP r 501

Chain	Residue
r	GLN11
r	CYS12
r	GLN15
r	ASN99
r	SER138
r	GLY141
r	GLY142
r	THR143
r	GLY144
r	ASP177
r	ASN204
r	PHE222
r	ASN226

site_id	AI7
Number of Residues	11
Details	binding site for residue TA1 r 502

Chain	Residue
r	GLU22
r	VAL23
r	HIS227
r	LEU228
r	SER234
r	LEU273
r	THR274
r	GLN279
r	LYS359
r	GLY360
r	LEU361

site_id	AI8
Number of Residues	18
Details	binding site for residue GTP s 501

Chain	Residue
a	LYS252
s	GLY10
s	GLN11
s	ALA12
s	GLN15
s	GLU71
s	ALA99
s	ALA100
s	ASN101
s	GLY144
s	THR145
s	GLY146
s	THR179
s	ASN206
s	TYR224
s	LEU227
s	ASN228
s	MG502

site_id	AI9
Number of Residues	2
Details	binding site for residue MG s 502

Chain	Residue
s	GLU71
s	GTP501

site_id	AJ1
Number of Residues	13
Details	binding site for residue GDP t 501

Chain	Residue
t	GLN11
t	CYS12
t	GLN15
t	ASN99
t	SER138
t	GLY141
t	GLY142
t	THR143
t	GLY144
t	ASP177
t	PHE222
t	LEU225
t	ASN226

site_id	AJ2
Number of Residues	14
Details	binding site for residue TA1 t 502

Chain	Residue
t	GLU22
t	VAL23
t	ASP26
t	GLU27
t	LEU215
t	ASP224
t	HIS227
t	LEU228
t	SER234
t	THR274
t	GLN279
t	LYS359
t	GLY360
t	LEU361

site_id	AJ3
Number of Residues	13
Details	binding site for residue GDP u 501

Chain	Residue
u	GLN11
u	CYS12
u	GLN15
u	ALA97
u	GLY141
u	GLY142
u	THR143
u	GLY144
u	ASP177
u	ASN204
u	PHE222
u	LEU225
u	ASN226

site_id	AJ4
Number of Residues	13
Details	binding site for residue TA1 u 502

Chain	Residue
u	VAL23
u	LEU215
u	HIS227
u	LEU228
u	SER234
u	LEU273
u	THR274
u	ARG276
u	GLN279
u	PRO358
u	LYS359
u	GLY360
u	LEU361

site_id	AJ5
Number of Residues	13
Details	binding site for residue GDP v 501

Chain	Residue
Y	LEU248
v	GLN11
v	CYS12
v	GLN15
v	ALA97
v	GLY141
v	GLY142
v	THR143
v	GLY144
v	ASP177
v	ASN204
v	PHE222
v	ASN226

site_id	AJ6
Number of Residues	13
Details	binding site for residue TA1 v 502

Chain	Residue
v	VAL23
v	LEU215
v	HIS227
v	LEU228
v	ALA231
v	SER234
v	THR274
v	ARG276
v	GLN279
v	PRO358
v	LYS359
v	GLY360
v	LEU361

site_id	AJ7
Number of Residues	12
Details	binding site for residue GDP w 501

Chain	Residue
w	GLN11
w	CYS12
w	GLN15
w	ALA97
w	ASN99
w	GLY141
w	GLY142
w	THR143
w	GLY144
w	ASP177
w	PHE222
w	ASN226

site_id	AJ8
Number of Residues	13
Details	binding site for residue TA1 w 502

Chain	Residue
w	VAL23
w	GLU27
w	LEU215
w	HIS227
w	LEU228
w	SER234
w	THR274
w	ARG276
w	GLN279
w	PRO358
w	LYS359
w	GLY360
w	LEU361

site_id	AJ9
Number of Residues	19
Details	binding site for residue GTP y 501

Chain	Residue
p	LYS252
p	MG503
y	GLY10
y	GLN11
y	ALA12
y	GLN15
y	GLU71
y	ASP98
y	ALA99
y	ALA100
y	ASN101
y	GLY143
y	GLY144
y	THR145
y	GLY146
y	THR179
y	ASN206
y	TYR224
y	ASN228

site_id	AK1
Number of Residues	20
Details	binding site for residue GTP 0 501

Chain	Residue
0	GLY10
0	GLN11
0	ALA12
0	GLN15
0	GLU71
0	ASP98
0	ALA99
0	ALA100
0	ASN101
0	GLY143
0	GLY144
0	THR145
0	GLY146
0	THR179
0	ASN206
0	TYR224
0	LEU227
0	ASN228
0	MG502
r	LYS252

site_id	AK2
Number of Residues	3
Details	binding site for residue MG 0 502

Chain	Residue
0	GLU71
0	GTP501
r	LYS252

site_id	AK3
Number of Residues	19
Details	binding site for residue GTP 1 501

Chain	Residue
1	GLY10
1	GLN11
1	ALA12
1	GLN15
1	GLU71
1	ALA99
1	ALA100
1	ASN101
1	GLY143
1	GLY144
1	THR145
1	GLY146
1	THR179
1	ASN206
1	TYR224
1	LEU227
1	ASN228
1	MG502
v	LYS252

site_id	AK4
Number of Residues	2
Details	binding site for residue MG 1 502

Chain	Residue
1	GLU71
1	GTP501

site_id	AK5
Number of Residues	13
Details	binding site for residue GDP 4 501

Chain	Residue
4	GLN11
4	CYS12
4	GLN15
4	ILE16
4	ALA97
4	ASN99
4	GLY141
4	GLY142
4	THR143
4	GLY144
4	ASP177
4	PHE222
4	ASN226

site_id	AK6
Number of Residues	14
Details	binding site for residue TA1 4 502

Chain	Residue
4	VAL23
4	GLU27
4	LEU215
4	HIS227
4	LEU228
4	SER234
4	LEU273
4	THR274
4	ARG276
4	GLN279
4	PRO358
4	LYS359
4	GLY360
4	LEU361

site_id	AK7
Number of Residues	18
Details	binding site for residue GTP 5 501

Chain	Residue
5	GLY10
5	GLN11
5	ALA12
5	GLN15
5	GLU71
5	ALA99
5	ALA100
5	ASN101
5	GLY143
5	GLY144
5	THR145
5	GLY146
5	ASN206
5	TYR224
5	LEU227
5	ASN228
5	MG502
u	LYS252

site_id	AK8
Number of Residues	2
Details	binding site for residue MG 5 502

Chain	Residue
5	GLU71
5	GTP501

site_id	AK9
Number of Residues	20
Details	binding site for residue GTP 6 501

Chain	Residue
4	LYS252
6	GLY10
6	GLN11
6	ALA12
6	GLN15
6	GLU71
6	ASP98
6	ALA99
6	ALA100
6	ASN101
6	GLY143
6	GLY144
6	THR145
6	GLY146
6	THR179
6	ASN206
6	TYR224
6	LEU227
6	ASN228
6	MG502

site_id	AL1
Number of Residues	2
Details	binding site for residue MG 6 502

Chain	Residue
6	GLU71
6	GTP501

site_id	AL2
Number of Residues	17
Details	binding site for residue GTP 7 501

Chain	Residue
7	GLY10
7	GLN11
7	ALA12
7	GLN15
7	GLU71
7	ALA99
7	ALA100
7	ASN101
7	GLY143
7	GLY144
7	THR145
7	GLY146
7	ASN206
7	TYR224
7	ASN228
7	MG502
w	LYS252

site_id	AL3
Number of Residues	2
Details	binding site for residue MG 7 502

Chain	Residue
7	GLU71
7	GTP501

site_id	AL4
Number of Residues	15
Details	binding site for residue GDP 8 501

Chain	Residue
8	GLN11
8	CYS12
8	GLN15
8	ASN99
8	SER138
8	GLY141
8	GLY142
8	THR143
8	GLY144
8	ASP177
8	ASN204
8	PHE222
8	LEU225
8	ASN226
F	LEU248

site_id	AL5
Number of Residues	14
Details	binding site for residue TA1 8 502

Chain	Residue
8	ASP26
8	GLU27
8	LEU215
8	ASP224
8	HIS227
8	LEU228
8	SER234
8	THR274
8	ARG276
8	GLN279
8	PRO358
8	LYS359
8	GLY360
8	LEU361

site_id	AL6
Number of Residues	15
Details	binding site for residue GDP 9 501

Chain	Residue
9	GLN11
9	CYS12
9	GLN15
9	SER138
9	GLY141
9	GLY142
9	THR143
9	GLY144
9	ASP177
9	ASN204
9	PHE222
9	LEU225
9	ASN226
s	LEU248
s	GLU254

site_id	AL7
Number of Residues	13
Details	binding site for residue TA1 9 502

Chain	Residue
9	ASP26
9	GLU27
9	HIS227
9	LEU228
9	SER234
9	THR274
9	ARG276
9	GLN279
9	PRO358
9	LYS359
9	GLY360
9	LEU361
9	VAL23

Functional Information from PROSITE/UniProt

site_id	PS00227
Number of Residues	7
Details	TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG

Chain	Residue	Details
a	GLY140-GLY146
0	GLY142-GLY148

site_id	PS00228
Number of Residues	4
Details	TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI

Chain	Residue	Details
a	MET1-ILE4

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. SLGGqdDnALVLWDV

Chain	Residue	Details
B	SER120-VAL134
B	CYS484-LEU498

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	24
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	192
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"2441392","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	168
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q13509","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)