6VCY

Crystal structure of Arabidopsis thaliana S-adenosylmethionine Synthase 1 (AtMAT1) in complex with 5'-methylthioadenosine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004478	molecular_function	methionine adenosyltransferase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006556	biological_process	S-adenosylmethionine biosynthetic process
A	0006730	biological_process	one-carbon metabolic process
A	0009505	cellular_component	plant-type cell wall
A	0009693	biological_process	ethylene biosynthetic process
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue SO4 A 401

Chain	Residue
A	HIS15
A	HOH542
A	HOH590
A	ASP17
A	ASP122
A	LYS169
A	LYS253
A	SO4402
A	MG404
A	MTA406
A	HOH507

---

site_id	AC2
Number of Residues	9
Details	binding site for residue SO4 A 402

Chain	Residue
A	ASP17
A	ARG252
A	LYS253
A	ALA269
A	LYS273
A	SO4401
A	MG404
A	HOH506
A	HOH507

---

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 403

Chain	Residue
A	PRO220
A	GLU221
A	HOH520
A	HOH668

---

site_id	AC4
Number of Residues	6
Details	binding site for residue MG A 404

Chain	Residue
A	ASP17
A	SO4401
A	SO4402
A	HOH507
A	HOH545
A	HOH590

---

site_id	AC5
Number of Residues	2
Details	binding site for residue GOL A 405

Chain	Residue
A	ASP321
A	HOH578

---

site_id	AC6
Number of Residues	13
Details	binding site for residue MTA A 406

Chain	Residue
A	HIS15
A	GLY121
A	ASP122
A	ASP167
A	SER194
A	SER235
A	ARG237
A	PHE238
A	ASP246
A	SO4401
A	HOH531
A	HOH593
A	HOH732

---

site_id	AC7
Number of Residues	1
Details	binding site for residue CL A 407

Chain	Residue
A	ARG373

---

site_id	AC8
Number of Residues	2
Details	binding site for residue CL A 408

Chain	Residue
A	VAL239
A	ILE240

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CL A 409

Chain	Residue
A	ASP342
A	LYS384
A	HOH609
A	HOH611
A	HOH790

---

site_id	AD1
Number of Residues	5
Details	binding site for residue CL A 410

Chain	Residue
A	GLY121
A	ASP122
A	LYS277
A	VAL278
A	HOH719

---

site_id	AD2
Number of Residues	4
Details	binding site for residue CL A 411

Chain	Residue
A	ARG70
A	LYS91
A	VAL92
A	HOH716

---

site_id	AD3
Number of Residues	2
Details	binding site for residue CL A 412

Chain	Residue
A	ASP198
A	GLU199

---

site_id	AD4
Number of Residues	1
Details	binding site for residue CL A 413

Chain	Residue
A	ASP102

---

Functional Information from PROSITE/UniProt

site_id	PS00376
Number of Residues	11
Details	ADOMET_SYNTHASE_1 S-adenosylmethionine synthase signature 1. GAGDQGhmfGY

Chain	Residue	Details
A	GLY119-TYR129

---

site_id	PS00377
Number of Residues	9
Details	ADOMET_SYNTHASE_2 S-adenosylmethionine synthase signature 2. GGGAFSgKD

Chain	Residue	Details
A	GLY266-ASP274

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P13444

Chain	Residue	Details
A	GLU9

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: in other chain => ECO:0000250|UniProtKB:Q00266

Chain	Residue	Details
A	HIS15
A	ASP167
A	SER235

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P0A817

Chain	Residue	Details
A	GLU43
A	ASP246
A	ALA269
A	LYS273

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: in other chain => ECO:0000250|UniProtKB:P0A817

Chain	Residue	Details
A	GLU56
A	GLN99
A	ARG252
A	LYS277

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: S-nitrosocysteine => ECO:0000269|PubMed:16365035

Chain	Residue	Details
A	CYS114

---