6VCX

Crystal structure of Arabidopsis thaliana S-adenosylmethionine Synthase 1 (AtMAT1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004478	molecular_function	methionine adenosyltransferase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006556	biological_process	S-adenosylmethionine biosynthetic process
A	0006730	biological_process	one-carbon metabolic process
A	0009505	cellular_component	plant-type cell wall
A	0009693	biological_process	ethylene biosynthetic process
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue SO4 A 401

Chain	Residue
A	ASP17
A	HOH590
A	HOH602
A	HOH646
A	HOH811
A	ARG252
A	LYS253
A	ALA269
A	LYS273
A	ASP279
A	SO4403
A	MG404
A	HOH502

---

site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 402

Chain	Residue
A	PRO220
A	GLU221
A	HOH535
A	HOH748

---

site_id	AC3
Number of Residues	10
Details	binding site for residue SO4 A 403

Chain	Residue
A	HIS15
A	ASP17
A	ASP122
A	LYS169
A	LYS253
A	SO4401
A	MG404
A	HOH502
A	HOH506
A	HOH602

---

site_id	AC4
Number of Residues	7
Details	binding site for residue MG A 404

Chain	Residue
A	ASP17
A	SO4401
A	SO4403
A	HOH502
A	HOH590
A	HOH595
A	HOH811

---

site_id	AC5
Number of Residues	6
Details	binding site for residue MG A 405

Chain	Residue
A	ASP64
A	HOH607
A	HOH797
A	HOH853
A	HOH902
A	HOH997

---

site_id	AC6
Number of Residues	4
Details	binding site for residue CL A 406

Chain	Residue
A	ARG237
A	VAL239
A	ILE240
A	HOH761

---

site_id	AC7
Number of Residues	3
Details	binding site for residue CL A 407

Chain	Residue
A	ASP342
A	LYS384
A	HOH908

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CL A 408

Chain	Residue
A	GLY121
A	ASP122
A	LYS277
A	VAL278
A	HOH825
A	HOH940

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CL A 409

Chain	Residue
A	ARG70
A	LYS91
A	VAL92
A	HOH784
A	HOH833

---

site_id	AD1
Number of Residues	2
Details	binding site for residue CL A 410

Chain	Residue
A	ASP198
A	GLU199

---

site_id	AD2
Number of Residues	2
Details	binding site for residue CL A 411

Chain	Residue
A	LYS113
A	GLY119

---

site_id	AD3
Number of Residues	4
Details	binding site for residue CL A 412

Chain	Residue
A	VAL318
A	LYS338
A	HOH832
A	HOH996

---

site_id	AD4
Number of Residues	3
Details	binding site for residue CL A 413

Chain	Residue
A	PRO101
A	ASP102
A	VAL107

---

site_id	AD5
Number of Residues	14
Details	binding site for residue BTB A 414

Chain	Residue
A	GLU13
A	GLN22
A	LYS157
A	LEU363
A	LYS364
A	HOH501
A	HOH515
A	HOH520
A	HOH531
A	HOH632
A	HOH679
A	HOH779
A	HOH791
A	HOH829

---

Functional Information from PROSITE/UniProt

site_id	PS00376
Number of Residues	11
Details	ADOMET_SYNTHASE_1 S-adenosylmethionine synthase signature 1. GAGDQGhmfGY

Chain	Residue	Details
A	GLY119-TYR129

---

site_id	PS00377
Number of Residues	9
Details	ADOMET_SYNTHASE_2 S-adenosylmethionine synthase signature 2. GGGAFSgKD

Chain	Residue	Details
A	GLY266-ASP274

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P13444

Chain	Residue	Details
A	GLU9

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: in other chain => ECO:0000250|UniProtKB:Q00266

Chain	Residue	Details
A	ASP167
A	SER235
A	HIS15

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P0A817

Chain	Residue	Details
A	ASP246
A	ALA269
A	LYS273
A	GLU43

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: in other chain => ECO:0000250|UniProtKB:P0A817

Chain	Residue	Details
A	GLN99
A	ARG252
A	LYS277
A	GLU56

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: S-nitrosocysteine => ECO:0000269|PubMed:16365035

Chain	Residue	Details
A	CYS114

---