Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6VCH

Crystal structure of Nitrosotalea devanaterra carotenoid cleavage dioxygenase in complex with 3-hydroxy-beta-apo-14'-carotenal

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003834	molecular_function	beta-carotene 15,15'-dioxygenase activity
A	0010436	molecular_function	carotenoid dioxygenase activity
A	0016121	biological_process	carotene catabolic process
A	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
A	0042574	biological_process	retinal metabolic process
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
B	0003834	molecular_function	beta-carotene 15,15'-dioxygenase activity
B	0010436	molecular_function	carotenoid dioxygenase activity
B	0016121	biological_process	carotene catabolic process
B	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
B	0042574	biological_process	retinal metabolic process
B	0046872	molecular_function	metal ion binding
B	0051213	molecular_function	dioxygenase activity
C	0003834	molecular_function	beta-carotene 15,15'-dioxygenase activity
C	0010436	molecular_function	carotenoid dioxygenase activity
C	0016121	biological_process	carotene catabolic process
C	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
C	0042574	biological_process	retinal metabolic process
C	0046872	molecular_function	metal ion binding
C	0051213	molecular_function	dioxygenase activity
D	0003834	molecular_function	beta-carotene 15,15'-dioxygenase activity
D	0010436	molecular_function	carotenoid dioxygenase activity
D	0016121	biological_process	carotene catabolic process
D	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
D	0042574	biological_process	retinal metabolic process
D	0046872	molecular_function	metal ion binding
D	0051213	molecular_function	dioxygenase activity
E	0003834	molecular_function	beta-carotene 15,15'-dioxygenase activity
E	0010436	molecular_function	carotenoid dioxygenase activity
E	0016121	biological_process	carotene catabolic process
E	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
E	0042574	biological_process	retinal metabolic process
E	0046872	molecular_function	metal ion binding
E	0051213	molecular_function	dioxygenase activity
F	0003834	molecular_function	beta-carotene 15,15'-dioxygenase activity
F	0010436	molecular_function	carotenoid dioxygenase activity
F	0016121	biological_process	carotene catabolic process
F	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
F	0042574	biological_process	retinal metabolic process
F	0046872	molecular_function	metal ion binding
F	0051213	molecular_function	dioxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CO A 501

Chain	Residue
A	HIS172
A	HIS222
A	HIS289
A	HIS467
A	HOH604

site_id	AC2
Number of Residues	14
Details	binding site for residue QVM A 502

Chain	Residue
A	PHE120
A	THR121
A	ASN125
A	VAL126
A	THR139
A	GLU140
A	GLY167
A	HIS222
A	PHE252
A	HOH604
A	PHE58
A	ARG98
A	GLU99
A	PHE100

site_id	AC3
Number of Residues	3
Details	binding site for residue CL A 503

Chain	Residue
A	PRO242
A	LEU243
B	GLU216

site_id	AC4
Number of Residues	5
Details	binding site for residue CO B 501

Chain	Residue
B	HIS172
B	HIS222
B	HIS289
B	HIS467
B	HOH601

site_id	AC5
Number of Residues	6
Details	binding site for residue NA B 502

Chain	Residue
B	GLU354
B	SER378
B	THR379
B	GLN388
D	ALA382
D	SER383

site_id	AC6
Number of Residues	14
Details	binding site for residue QVM B 503

Chain	Residue
B	PHE58
B	ARG98
B	GLU99
B	PHE100
B	PHE120
B	THR121
B	ASN125
B	VAL126
B	THR139
B	GLU140
B	GLY167
B	HIS222
B	PHE252
B	HOH601

site_id	AC7
Number of Residues	5
Details	binding site for residue CO C 501

Chain	Residue
C	HIS172
C	HIS222
C	HIS289
C	HIS467
C	HOH604

site_id	AC8
Number of Residues	15
Details	binding site for residue QVM C 502

Chain	Residue
C	PHE58
C	ARG98
C	GLU99
C	PHE100
C	PHE120
C	THR121
C	ASN125
C	VAL126
C	THR139
C	GLU140
C	GLY167
C	HIS222
C	PHE252
C	HOH604
C	HOH647

site_id	AC9
Number of Residues	6
Details	binding site for residue NA C 503

Chain	Residue
A	ALA382
A	SER383
C	GLU354
C	SER378
C	THR379
C	GLN388

site_id	AD1
Number of Residues	5
Details	binding site for residue CO D 501

Chain	Residue
D	HIS172
D	HIS222
D	HIS289
D	HIS467
D	HOH605

site_id	AD2
Number of Residues	17
Details	binding site for residue QVM D 502

Chain	Residue
D	PHE58
D	ARG98
D	GLU99
D	PHE100
D	PHE120
D	THR121
D	ASN125
D	VAL126
D	THR139
D	GLU140
D	THR141
D	GLY167
D	HIS222
D	PHE252
D	HOH605
D	HOH629
D	HOH634

site_id	AD3
Number of Residues	5
Details	binding site for residue CO E 501

Chain	Residue
E	HOH605
E	HIS172
E	HIS222
E	HIS289
E	HIS467

site_id	AD4
Number of Residues	2
Details	binding site for residue CL E 502

Chain	Residue
E	ASN208
F	ASN208

site_id	AD5
Number of Residues	4
Details	binding site for residue CO F 1000

Chain	Residue
F	HIS172
F	HIS222
F	HIS289
F	HIS467

Functional Information from PROSITE/UniProt

site_id	PS00430
Number of Residues	30
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. maytvtnkfqlgfstlseeldl.............................................................................................ESLQVKGT

Chain	Residue	Details
A	MET1-THR30

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)