Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue NA A 501 |
Chain | Residue |
A | ASP60 |
A | HOH619 |
A | HOH633 |
A | HOH648 |
A | HOH658 |
A | HOH682 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue CL A 502 |
Chain | Residue |
A | THR74 |
A | ASN88 |
B | ARG41 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue CL A 503 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue CL A 504 |
Chain | Residue |
A | ILE54 |
A | LYS55 |
A | HOH707 |
site_id | AC5 |
Number of Residues | 35 |
Details | binding site for residue G6R B 201 |
Chain | Residue |
A | ARG8 |
A | ASP25 |
A | GLY27 |
A | ALA28 |
A | ASP29 |
A | ASP30 |
A | ILE47 |
A | GLY48 |
A | GLY49 |
A | ILE50 |
A | PRO81 |
A | VAL82 |
A | ILE84 |
A | HOH656 |
A | HOH685 |
A | HOH703 |
B | ARG8 |
B | ASP25 |
B | GLY27 |
B | ALA28 |
B | ASP29 |
B | ASP30 |
B | LYS45 |
B | ILE47 |
B | GLY48 |
B | GLY49 |
B | ILE50 |
B | PRO81 |
B | VAL82 |
B | ILE84 |
B | HOH306 |
B | HOH349 |
B | HOH363 |
B | HOH392 |
B | HOH397 |
site_id | AC6 |
Number of Residues | 1 |
Details | binding site for residue CL B 202 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue CL B 203 |
Chain | Residue |
B | THR74 |
B | ASN88 |
B | HOH330 |
B | HOH400 |
site_id | AC8 |
Number of Residues | 3 |
Details | binding site for residue CL B 204 |
Chain | Residue |
B | THR12 |
B | GOL205 |
B | HOH311 |
site_id | AC9 |
Number of Residues | 10 |
Details | binding site for residue GOL B 205 |
Chain | Residue |
A | GLN18 |
A | MET36 |
A | SER37 |
B | THR12 |
B | GLU65 |
B | ALA67 |
B | GLY68 |
B | CL204 |
B | HOH365 |
B | HOH418 |
site_id | AD1 |
Number of Residues | 5 |
Details | binding site for residue GOL B 206 |
Chain | Residue |
A | LYS70 |
A | ALA71 |
B | GLY40 |
B | HOH305 |
B | HOH407 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
Chain | Residue | Details |
A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP25 | |
B | ASP25 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | SITE: Cleavage; by viral protease => ECO:0000250 |
Chain | Residue | Details |
A | PHE99 | |
B | PHE99 | |