Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 501 |
| Chain | Residue |
| A | ASP60 |
| A | HOH619 |
| A | HOH633 |
| A | HOH648 |
| A | HOH658 |
| A | HOH682 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 502 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| B | ARG41 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 503 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 504 |
| Chain | Residue |
| A | ILE54 |
| A | LYS55 |
| A | HOH707 |
| site_id | AC5 |
| Number of Residues | 35 |
| Details | binding site for residue G6R B 201 |
| Chain | Residue |
| A | ARG8 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | HOH656 |
| A | HOH685 |
| A | HOH703 |
| B | ARG8 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | LYS45 |
| B | ILE47 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| B | PRO81 |
| B | VAL82 |
| B | ILE84 |
| B | HOH306 |
| B | HOH349 |
| B | HOH363 |
| B | HOH392 |
| B | HOH397 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 202 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 203 |
| Chain | Residue |
| B | THR74 |
| B | ASN88 |
| B | HOH330 |
| B | HOH400 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 204 |
| Chain | Residue |
| B | THR12 |
| B | GOL205 |
| B | HOH311 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 205 |
| Chain | Residue |
| A | GLN18 |
| A | MET36 |
| A | SER37 |
| B | THR12 |
| B | GLU65 |
| B | ALA67 |
| B | GLY68 |
| B | CL204 |
| B | HOH365 |
| B | HOH418 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 206 |
| Chain | Residue |
| A | LYS70 |
| A | ALA71 |
| B | GLY40 |
| B | HOH305 |
| B | HOH407 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
