6VAL
Cryo-EM structure of an undecameric chicken CALHM1 and human CALHM2 chimera
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003674 | molecular_function | molecular_function |
| A | 0005575 | cellular_component | cellular_component |
| A | 0006091 | biological_process | generation of precursor metabolites and energy |
| A | 0008218 | biological_process | bioluminescence |
| B | 0003674 | molecular_function | molecular_function |
| B | 0005575 | cellular_component | cellular_component |
| B | 0006091 | biological_process | generation of precursor metabolites and energy |
| B | 0008218 | biological_process | bioluminescence |
| C | 0003674 | molecular_function | molecular_function |
| C | 0005575 | cellular_component | cellular_component |
| C | 0006091 | biological_process | generation of precursor metabolites and energy |
| C | 0008218 | biological_process | bioluminescence |
| D | 0003674 | molecular_function | molecular_function |
| D | 0005575 | cellular_component | cellular_component |
| D | 0006091 | biological_process | generation of precursor metabolites and energy |
| D | 0008218 | biological_process | bioluminescence |
| E | 0003674 | molecular_function | molecular_function |
| E | 0005575 | cellular_component | cellular_component |
| E | 0006091 | biological_process | generation of precursor metabolites and energy |
| E | 0008218 | biological_process | bioluminescence |
| F | 0003674 | molecular_function | molecular_function |
| F | 0005575 | cellular_component | cellular_component |
| F | 0006091 | biological_process | generation of precursor metabolites and energy |
| F | 0008218 | biological_process | bioluminescence |
| G | 0003674 | molecular_function | molecular_function |
| G | 0005575 | cellular_component | cellular_component |
| G | 0006091 | biological_process | generation of precursor metabolites and energy |
| G | 0008218 | biological_process | bioluminescence |
| H | 0003674 | molecular_function | molecular_function |
| H | 0005575 | cellular_component | cellular_component |
| H | 0006091 | biological_process | generation of precursor metabolites and energy |
| H | 0008218 | biological_process | bioluminescence |
| I | 0003674 | molecular_function | molecular_function |
| I | 0005575 | cellular_component | cellular_component |
| I | 0006091 | biological_process | generation of precursor metabolites and energy |
| I | 0008218 | biological_process | bioluminescence |
| J | 0003674 | molecular_function | molecular_function |
| J | 0005575 | cellular_component | cellular_component |
| J | 0006091 | biological_process | generation of precursor metabolites and energy |
| J | 0008218 | biological_process | bioluminescence |
| K | 0003674 | molecular_function | molecular_function |
| K | 0005575 | cellular_component | cellular_component |
| K | 0006091 | biological_process | generation of precursor metabolites and energy |
| K | 0008218 | biological_process | bioluminescence |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 11 |
| Details | MOD_RES: (Z)-2,3-didehydrotyrosine => ECO:0000269|PubMed:8448132 |
| Chain | Residue | Details |
| A | TYR-185 | |
| J | TYR-185 | |
| K | TYR-185 | |
| B | TYR-185 | |
| C | TYR-185 | |
| D | TYR-185 | |
| E | TYR-185 | |
| F | TYR-185 | |
| G | TYR-185 | |
| H | TYR-185 | |
| I | TYR-185 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | CROSSLNK: 5-imidazolinone (Ser-Gly) => ECO:0000269|PubMed:8448132 |
| Chain | Residue | Details |
| A | THR-186 | |
| E | GLY-184 | |
| F | THR-186 | |
| F | GLY-184 | |
| G | THR-186 | |
| G | GLY-184 | |
| H | THR-186 | |
| H | GLY-184 | |
| I | THR-186 | |
| I | GLY-184 | |
| J | THR-186 | |
| A | GLY-184 | |
| J | GLY-184 | |
| K | THR-186 | |
| K | GLY-184 | |
| B | THR-186 | |
| B | GLY-184 | |
| C | THR-186 | |
| C | GLY-184 | |
| D | THR-186 | |
| D | GLY-184 | |
| E | THR-186 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 231 |
| Details | TRANSMEM: Helical; Name=S1 => ECO:0000269|PubMed:31776515, ECO:0007744|PDB:6UIV |
| Chain | Residue | Details |
| A | SER17-ASP38 | |
| J | SER17-ASP38 | |
| K | SER17-ASP38 | |
| B | SER17-ASP38 | |
| C | SER17-ASP38 | |
| D | SER17-ASP38 | |
| E | SER17-ASP38 | |
| F | SER17-ASP38 | |
| G | SER17-ASP38 | |
| H | SER17-ASP38 | |
| I | SER17-ASP38 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 88 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| A | PHE39-TYR47 | |
| J | PHE39-TYR47 | |
| K | PHE39-TYR47 | |
| B | PHE39-TYR47 | |
| C | PHE39-TYR47 | |
| D | PHE39-TYR47 | |
| E | PHE39-TYR47 | |
| F | PHE39-TYR47 | |
| G | PHE39-TYR47 | |
| H | PHE39-TYR47 | |
| I | PHE39-TYR47 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 253 |
| Details | TRANSMEM: Helical; Name=S2 => ECO:0000269|PubMed:31776515, ECO:0007744|PDB:6UIV |
| Chain | Residue | Details |
| A | ASN48-ASN71 | |
| J | ASN48-ASN71 | |
| K | ASN48-ASN71 | |
| B | ASN48-ASN71 | |
| C | ASN48-ASN71 | |
| D | ASN48-ASN71 | |
| E | ASN48-ASN71 | |
| F | ASN48-ASN71 | |
| G | ASN48-ASN71 | |
| H | ASN48-ASN71 | |
| I | ASN48-ASN71 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 330 |
| Details | TRANSMEM: Helical; Name=S3 => ECO:0000269|PubMed:31776515, ECO:0007744|PDB:6UIV |
| Chain | Residue | Details |
| A | CYS100-THR130 | |
| J | CYS100-THR130 | |
| K | CYS100-THR130 | |
| B | CYS100-THR130 | |
| C | CYS100-THR130 | |
| D | CYS100-THR130 | |
| E | CYS100-THR130 | |
| F | CYS100-THR130 | |
| G | CYS100-THR130 | |
| H | CYS100-THR130 | |
| I | CYS100-THR130 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 286 |
| Details | TRANSMEM: Helical; Name=S4 => ECO:0000269|PubMed:31776515, ECO:0007744|PDB:6UIV |
| Chain | Residue | Details |
| A | LEU178-LYS204 | |
| J | LEU178-LYS204 | |
| K | LEU178-LYS204 | |
| B | LEU178-LYS204 | |
| C | LEU178-LYS204 | |
| D | LEU178-LYS204 | |
| E | LEU178-LYS204 | |
| F | LEU178-LYS204 | |
| G | LEU178-LYS204 | |
| H | LEU178-LYS204 | |
| I | LEU178-LYS204 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1276 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | HIS205-SER321 | |
| J | HIS205-SER321 | |
| K | HIS205-SER321 | |
| B | HIS205-SER321 | |
| C | HIS205-SER321 | |
| D | HIS205-SER321 | |
| E | HIS205-SER321 | |
| F | HIS205-SER321 | |
| G | HIS205-SER321 | |
| H | HIS205-SER321 | |
| I | HIS205-SER321 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 11 |
| Details | SITE: Not N-glycosylated => ECO:0000269|PubMed:31776515 |
| Chain | Residue | Details |
| A | GLY165 | |
| J | GLY165 | |
| K | GLY165 | |
| B | GLY165 | |
| C | GLY165 | |
| D | GLY165 | |
| E | GLY165 | |
| F | GLY165 | |
| G | GLY165 | |
| H | GLY165 | |
| I | GLY165 |
