6VA5
Tudor Domain of Tumor suppressor p53BP1 with MFP-4184
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue QSS A 1701 |
| Chain | Residue |
| A | TRP1495 |
| A | ASN1498 |
| A | TYR1502 |
| A | ASP1521 |
| A | TYR1523 |
| A | ARG1562 |
| A | GLU1598 |
| A | TYR1605 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 1702 |
| Chain | Residue |
| A | SER1497 |
| A | ASN1498 |
| A | LEU1534 |
| A | HOH1838 |
| A | HOH1860 |
| A | HOH1876 |
| A | HOH1890 |
| A | LYS1494 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 1703 |
| Chain | Residue |
| A | ARG1490 |
| A | GLU1567 |
| A | LEU1568 |
| A | ARG1583 |
| A | HOH1816 |
| A | HOH1819 |
| A | HOH1825 |
| A | HOH1862 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1704 |
| Chain | Residue |
| A | LYS1530 |
| A | ARG1597 |
| A | HOH1806 |
| A | HOH1911 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 1705 |
| Chain | Residue |
| A | ARG1595 |
| A | LEU1596 |
| A | GLN1599 |
| A | HOH1823 |
| A | HOH1836 |
| A | HOH1849 |
| A | HOH1873 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1706 |
| Chain | Residue |
| A | ARG1562 |
| A | LYS1563 |
| A | GLU1564 |
| A | HOH1824 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 119 |
| Details | Region: {"description":"Tudor-like","evidences":[{"source":"PubMed","id":"17190600","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | Region: {"description":"Interaction with dimethylated histone H4","evidences":[{"source":"PubMed","id":"17190600","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
