Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003924 | molecular_function | GTPase activity |
A | 0005525 | molecular_function | GTP binding |
A | 0007165 | biological_process | signal transduction |
A | 0016020 | cellular_component | membrane |
B | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
B | 0007264 | biological_process | small GTPase-mediated signal transduction |
C | 0003924 | molecular_function | GTPase activity |
C | 0005525 | molecular_function | GTP binding |
C | 0007165 | biological_process | signal transduction |
C | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 30 |
Details | binding site for residue GNP A 201 |
Chain | Residue |
A | GLY12 |
A | ASP30 |
A | GLU31 |
A | TYR32 |
A | PRO34 |
A | THR35 |
A | GLY60 |
A | GLN61 |
A | ASN116 |
A | LYS117 |
A | ASP119 |
A | GLY13 |
A | LEU120 |
A | SER145 |
A | ALA146 |
A | LYS147 |
A | MG202 |
A | HOH320 |
A | HOH344 |
A | HOH363 |
A | HOH367 |
A | HOH379 |
A | VAL14 |
A | HOH426 |
A | GLY15 |
A | LYS16 |
A | SER17 |
A | ALA18 |
A | PHE28 |
A | VAL29 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue MG A 202 |
Chain | Residue |
A | SER17 |
A | THR35 |
A | GNP201 |
A | HOH320 |
A | HOH344 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue QTG B 2001 |
Chain | Residue |
B | MET878 |
B | ASN879 |
B | PHE890 |
B | LEU901 |
B | GLU902 |
B | HIS905 |
B | HOH2661 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue FMT B 2002 |
Chain | Residue |
B | GLN566 |
B | MET567 |
B | HIS616 |
B | MET617 |
B | HOH2205 |
B | HOH2242 |
B | HOH2291 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue FMT B 2003 |
Chain | Residue |
A | ARG128 |
B | ARG767 |
B | PRO768 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue FMT B 2004 |
Chain | Residue |
A | GLU37 |
A | MET67 |
A | GLN70 |
B | ALA619 |
B | ARG688 |
B | HOH2136 |
B | HOH2207 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue FMT B 2005 |
Chain | Residue |
B | GLU611 |
B | TYR615 |
B | HIS616 |
B | ARG647 |
B | TYR681 |
B | HOH2227 |
site_id | AC8 |
Number of Residues | 1 |
Details | binding site for residue FMT B 2006 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue GOL B 2007 |
Chain | Residue |
B | SER793 |
B | ASP794 |
B | PRO978 |
B | TYR979 |
B | HOH2304 |
site_id | AD1 |
Number of Residues | 5 |
Details | binding site for residue GOL B 2008 |
Chain | Residue |
B | ARG786 |
B | GLU864 |
B | VAL1040 |
B | HOH2101 |
B | HOH2192 |
site_id | AD2 |
Number of Residues | 8 |
Details | binding site for residue FMT C 201 |
Chain | Residue |
B | LEU938 |
C | GLY15 |
C | LYS16 |
C | SER17 |
C | ALA59 |
C | HOH307 |
C | HOH382 |
C | HOH414 |
site_id | AD3 |
Number of Residues | 6 |
Details | binding site for residue NA C 202 |
Chain | Residue |
C | ASN85 |
C | ASN86 |
C | THR87 |
C | THR124 |
C | HOH471 |
C | HOH474 |
Functional Information from PROSITE/UniProt
site_id | PS00720 |
Number of Residues | 34 |
Details | RASGEF Ras Guanine-nucleotide exchange factors domain signature. VPFfGiyLtNIlkteegnpevlkrhgkel.................INFsK |
Chain | Residue | Details |
B | VAL927-LYS960 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
C | GLY13 | |
C | VAL29 | |
C | ALA59 | |
C | ASN116 | |
C | SER145 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | MOD_RES: N-acetylmethionine; in GTPase HRas; alternate => ECO:0000269|Ref.12 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: N-acetylthreonine; in GTPase HRas, N-terminally processed => ECO:0000269|Ref.12 |
Chain | Residue | Details |
C | CYS118 | |
Chain | Residue | Details |
C | THR35 | |