6V8P

Structure of DNA Polymerase Zeta (Apo)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000724	biological_process	double-strand break repair via homologous recombination
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005739	cellular_component	mitochondrion
A	0006260	biological_process	DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0008270	molecular_function	zinc ion binding
A	0016035	cellular_component	zeta DNA polymerase complex
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019985	biological_process	translesion synthesis
A	0034061	molecular_function	DNA polymerase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0070987	biological_process	error-free translesion synthesis
D	0000785	cellular_component	chromatin
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005739	cellular_component	mitochondrion
D	0006260	biological_process	DNA replication
D	0006281	biological_process	DNA repair
D	0006974	biological_process	DNA damage response
D	0016035	cellular_component	zeta DNA polymerase complex
D	0042276	biological_process	error-prone translesion synthesis
D	0070987	biological_process	error-free translesion synthesis
E	0000785	cellular_component	chromatin
E	0003887	molecular_function	DNA-directed DNA polymerase activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005739	cellular_component	mitochondrion
E	0006260	biological_process	DNA replication
E	0006281	biological_process	DNA repair
E	0006974	biological_process	DNA damage response
E	0016035	cellular_component	zeta DNA polymerase complex
E	0042276	biological_process	error-prone translesion synthesis
E	0070987	biological_process	error-free translesion synthesis
F	0003677	molecular_function	DNA binding
F	0003887	molecular_function	DNA-directed DNA polymerase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005739	cellular_component	mitochondrion
F	0005829	cellular_component	cytosol
F	0006259	biological_process	DNA metabolic process
F	0006260	biological_process	DNA replication
F	0006271	biological_process	DNA strand elongation involved in DNA replication
F	0006272	biological_process	leading strand elongation
F	0006273	biological_process	lagging strand elongation
F	0006278	biological_process	RNA-templated DNA biosynthetic process
F	0006281	biological_process	DNA repair
F	0006284	biological_process	base-excision repair
F	0006289	biological_process	nucleotide-excision repair
F	0006298	biological_process	mismatch repair
F	0006301	biological_process	DNA damage tolerance
F	0008310	molecular_function	single-stranded DNA 3'-5' DNA exonuclease activity
F	0016035	cellular_component	zeta DNA polymerase complex
F	0016740	molecular_function	transferase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0034061	molecular_function	DNA polymerase activity
F	0042276	biological_process	error-prone translesion synthesis
F	0043137	biological_process	DNA replication, removal of RNA primer
F	0043625	cellular_component	delta DNA polymerase complex
F	0071897	biological_process	DNA biosynthetic process
G	0000510	molecular_function	H3-H4 histone complex chaperone activity
G	0000727	biological_process	double-strand break repair via break-induced replication
G	0003887	molecular_function	DNA-directed DNA polymerase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005739	cellular_component	mitochondrion
G	0006259	biological_process	DNA metabolic process
G	0006260	biological_process	DNA replication
G	0006272	biological_process	leading strand elongation
G	0006273	biological_process	lagging strand elongation
G	0006277	biological_process	DNA amplification
G	0006278	biological_process	RNA-templated DNA biosynthetic process
G	0006284	biological_process	base-excision repair
G	0006289	biological_process	nucleotide-excision repair
G	0008310	molecular_function	single-stranded DNA 3'-5' DNA exonuclease activity
G	0016035	cellular_component	zeta DNA polymerase complex
G	0016740	molecular_function	transferase activity
G	0016779	molecular_function	nucleotidyltransferase activity
G	0042276	biological_process	error-prone translesion synthesis
G	0043137	biological_process	DNA replication, removal of RNA primer
G	0043625	cellular_component	delta DNA polymerase complex

Functional Information from PROSITE/UniProt

site_id	PS00116
Number of Residues	9
Details	DNA_POLYMERASE_B DNA polymerase family B signature. YGDTDSLFV

Chain	Residue	Details
A	TYR1140-VAL1148

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	27
Details	Motif: {"description":"CysB motif","evidences":[{"source":"UniProtKB","id":"P15436","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P15436","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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