Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003714 | molecular_function | transcription corepressor activity |
A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue CA A 401 |
Chain | Residue |
A | HOH506 |
A | HOH508 |
A | HOH515 |
A | HOH520 |
A | HOH662 |
A | HOH700 |
site_id | AC2 |
Number of Residues | 20 |
Details | binding site for residue AMP A 402 |
Chain | Residue |
A | ARG184 |
A | TYR203 |
A | ASP204 |
A | PRO205 |
A | TYR206 |
A | LEU207 |
A | CYS237 |
A | ASN240 |
A | ASN243 |
A | HOH511 |
A | HOH514 |
A | HOH523 |
A | HOH540 |
A | HOH541 |
A | HOH555 |
A | HOH564 |
A | HOH597 |
A | ILE180 |
A | GLY181 |
A | GLY183 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue CL A 403 |
Chain | Residue |
A | HIS77 |
A | ARG97 |
A | HOH653 |
site_id | AC4 |
Number of Residues | 2 |
Details | binding site for residue CL A 404 |
Chain | Residue |
A | SER324 |
A | ARG328 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue CL A 405 |
Chain | Residue |
A | ALA170 |
A | ARG171 |
A | GLU321 |
A | GLN322 |
Functional Information from PROSITE/UniProt
site_id | PS00671 |
Number of Residues | 17 |
Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MRqGaFLVNtARGgLVD |
Chain | Residue | Details |
A | MET255-ASP271 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: ACT_SITE => ECO:0000250 |
Chain | Residue | Details |
A | ARG266 | |
A | GLU295 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor => ECO:0000250 |
Chain | Residue | Details |
A | HIS315 | |
site_id | SWS_FT_FI3 |
Number of Residues | 7 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | SER100 | |
A | ILE180 | |
A | ASP204 | |
A | CYS237 | |
A | THR264 | |
A | ASP290 | |
A | HIS315 | |
Chain | Residue | Details |
A | ASN375 | |
Chain | Residue | Details |
A | SER300 | |