Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003714 | molecular_function | transcription corepressor activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | HOH506 |
| A | HOH508 |
| A | HOH515 |
| A | HOH520 |
| A | HOH662 |
| A | HOH700 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue AMP A 402 |
| Chain | Residue |
| A | ARG184 |
| A | TYR203 |
| A | ASP204 |
| A | PRO205 |
| A | TYR206 |
| A | LEU207 |
| A | CYS237 |
| A | ASN240 |
| A | ASN243 |
| A | HOH511 |
| A | HOH514 |
| A | HOH523 |
| A | HOH540 |
| A | HOH541 |
| A | HOH555 |
| A | HOH564 |
| A | HOH597 |
| A | ILE180 |
| A | GLY181 |
| A | GLY183 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | HIS77 |
| A | ARG97 |
| A | HOH653 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | SER324 |
| A | ARG328 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | ALA170 |
| A | ARG171 |
| A | GLU321 |
| A | GLN322 |
Functional Information from PROSITE/UniProt
| site_id | PS00671 |
| Number of Residues | 17 |
| Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MRqGaFLVNtARGgLVD |
| Chain | Residue | Details |
| A | MET255-ASP271 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG266 | |
| A | GLU295 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS315 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER100 | |
| A | ILE180 | |
| A | ASP204 | |
| A | CYS237 | |
| A | THR264 | |
| A | ASP290 | |
| A | HIS315 | |
| Chain | Residue | Details |
| A | ASN375 | |
| Chain | Residue | Details |
| A | SER300 | |
