6V86
Parainfluenza virus 5 L-P complex with an alternate conformation of the CD-MTase-CTD module
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001172 | biological_process | RNA-templated transcription |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006370 | biological_process | 7-methylguanosine mRNA capping |
| A | 0006397 | biological_process | mRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0032259 | biological_process | methylation |
| A | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| A | 0044423 | cellular_component | virion component |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0106005 | biological_process | RNA 5'-cap (guanine-N7)-methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 2301 |
| Chain | Residue |
| A | CYS1136 |
| A | ILE1138 |
| A | GLU1168 |
| A | ILE1169 |
| A | CYS1373 |
| A | CYS1374 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2302 |
| Chain | Residue |
| A | HIS1368 |
| A | CYS1181 |
| A | CYS1184 |
| A | HIS1366 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; for GDP polyribonucleotidyltransferase","evidences":[{"source":"UniProtKB","id":"P03523","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"For mRNA (guanine-N(7)-)-methyltransferase and mRNA (nucleoside-2'-O-)-methyltransferase","evidences":[{"source":"UniProtKB","id":"Q06996","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For mRNA (guanine-N(7)-)-methyltransferase and mRNA (nucleoside-2'-O-)-methyltransferase","evidences":[{"source":"UniProtKB","id":"P03523","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P28887","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32075920","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6V85","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6V86","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32075920","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6V86","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 108 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
