6V7A

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (CD2) complexed with NF2657

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000118	cellular_component	histone deacetylase complex
A	0004407	molecular_function	histone deacetylase activity
A	0006325	biological_process	chromatin organization
A	0016575	biological_process	histone deacetylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 801

Chain	Residue
A	ASP612
A	HIS614
A	ASP705
A	QQG804

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site_id	AC2
Number of Residues	5
Details	binding site for residue K A 802

Chain	Residue
A	ASP610
A	ASP612
A	HIS614
A	SER633
A	LEU634

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site_id	AC3
Number of Residues	5
Details	binding site for residue K A 803

Chain	Residue
A	PHE623
A	ASP626
A	VAL629
A	TYR662
A	HOH924

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site_id	AC4
Number of Residues	18
Details	binding site for residue QQG A 804

Chain	Residue
A	ASN530
A	SER531
A	HIS573
A	HIS574
A	GLY582
A	PHE583
A	ASP612
A	HIS614
A	PHE643
A	HIS684
A	ASP705
A	TYR745
A	SER796
A	LEU797
A	ARG798
A	ZN801
A	HOH982
A	HOH984

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