6V43
Crystal structure of the flavin oxygenase with cofactor and substrate bound involved in folate catabolism
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004458 | molecular_function | D-lactate dehydrogenase (cytochrome) activity |
| A | 0008720 | molecular_function | D-lactate dehydrogenase (NAD+) activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0071949 | molecular_function | FAD binding |
| A | 1903457 | biological_process | lactate catabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004458 | molecular_function | D-lactate dehydrogenase (cytochrome) activity |
| B | 0008720 | molecular_function | D-lactate dehydrogenase (NAD+) activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0071949 | molecular_function | FAD binding |
| B | 1903457 | biological_process | lactate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue LUZ A 501 |
| Chain | Residue |
| A | GLY81 |
| A | FAD502 |
| A | ASN82 |
| A | TYR83 |
| A | GLN85 |
| A | GLY152 |
| A | GLY153 |
| A | SER154 |
| A | HIS198 |
| A | ASN321 |
| site_id | AC2 |
| Number of Residues | 34 |
| Details | binding site for residue FAD A 502 |
| Chain | Residue |
| A | PRO75 |
| A | ARG76 |
| A | GLY77 |
| A | THR78 |
| A | GLY79 |
| A | THR80 |
| A | GLY81 |
| A | ASN82 |
| A | GLN85 |
| A | ALA86 |
| A | LEU97 |
| A | PRO115 |
| A | PRO138 |
| A | SER139 |
| A | THR140 |
| A | ALA144 |
| A | THR145 |
| A | GLY148 |
| A | PHE149 |
| A | ALA151 |
| A | GLY153 |
| A | SER154 |
| A | GLY155 |
| A | TYR200 |
| A | GLY201 |
| A | GLY204 |
| A | ILE206 |
| A | TRP320 |
| A | ASN321 |
| A | HIS322 |
| A | LUZ501 |
| A | HOH627 |
| A | HOH825 |
| B | MSE3 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue LUZ B 501 |
| Chain | Residue |
| B | GLY81 |
| B | ASN82 |
| B | TYR83 |
| B | GLN85 |
| B | GLY152 |
| B | GLY153 |
| B | SER154 |
| B | HIS198 |
| B | ASN321 |
| B | FAD502 |
| site_id | AC4 |
| Number of Residues | 36 |
| Details | binding site for residue FAD B 502 |
| Chain | Residue |
| B | PHE31 |
| B | TYR34 |
| B | PRO75 |
| B | ARG76 |
| B | GLY77 |
| B | THR78 |
| B | GLY79 |
| B | THR80 |
| B | GLY81 |
| B | ASN82 |
| B | GLN85 |
| B | ALA86 |
| B | LEU97 |
| B | PRO115 |
| B | PRO138 |
| B | SER139 |
| B | THR140 |
| B | ALA144 |
| B | THR145 |
| B | GLY148 |
| B | PHE149 |
| B | ALA151 |
| B | GLY153 |
| B | SER154 |
| B | GLY155 |
| B | TYR200 |
| B | GLY201 |
| B | GLY204 |
| B | ILE206 |
| B | TRP320 |
| B | ASN321 |
| B | HIS322 |
| B | ASN438 |
| B | LUZ501 |
| B | HOH1164 |
| B | HOH1371 |
