6V0A
Crystal structure of cytochrome c nitrite reductase from the bacterium Geobacter lovleyi with bound sulfate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| A | 0042597 | cellular_component | periplasmic space |
| B | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| B | 0042597 | cellular_component | periplasmic space |
| C | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| C | 0042597 | cellular_component | periplasmic space |
| D | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| D | 0042597 | cellular_component | periplasmic space |
| E | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| E | 0042597 | cellular_component | periplasmic space |
| F | 0042279 | molecular_function | nitrite reductase (cytochrome, ammonia-forming) activity |
| F | 0042597 | cellular_component | periplasmic space |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue HEC A 501 |
| Chain | Residue |
| A | TYR102 |
| A | CYS217 |
| A | HIS218 |
| A | TYR221 |
| A | HIS278 |
| A | ASN407 |
| A | HEC503 |
| A | SO4506 |
| A | HOH625 |
| A | HOH627 |
| A | HOH630 |
| A | ASN103 |
| A | HOH635 |
| A | HOH682 |
| A | PRO105 |
| A | GLN115 |
| A | ILE118 |
| A | ARG122 |
| A | CYS129 |
| A | CYS132 |
| A | LYS133 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue HEC A 502 |
| Chain | Residue |
| A | TYR49 |
| A | GLU52 |
| A | TYR53 |
| A | TRP56 |
| A | ALA170 |
| A | CYS171 |
| A | CYS174 |
| A | HIS175 |
| A | MET180 |
| A | LEU182 |
| A | ASN206 |
| A | ARG210 |
| A | LYS311 |
| A | ILE312 |
| A | SER313 |
| A | HIS315 |
| A | HEC503 |
| A | HOH673 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue HEC A 503 |
| Chain | Residue |
| A | PRO105 |
| A | ARG106 |
| A | GLY107 |
| A | HIS108 |
| A | TYR110 |
| A | MET111 |
| A | ASP114 |
| A | CYS132 |
| A | VAL213 |
| A | CYS214 |
| A | CYS217 |
| A | HIS218 |
| A | HIS301 |
| A | ILE317 |
| A | HEC501 |
| A | HEC502 |
| A | HEC504 |
| A | HOH664 |
| A | HOH680 |
| A | HOH709 |
| A | HOH746 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | binding site for residue HEC A 504 |
| Chain | Residue |
| A | SER68 |
| A | LYS71 |
| A | PRO105 |
| A | HIS218 |
| A | TYR284 |
| A | HIS290 |
| A | SER296 |
| A | CYS297 |
| A | CYS300 |
| A | HIS301 |
| A | SER319 |
| A | GLN347 |
| A | ASN407 |
| A | PHE411 |
| A | HIS412 |
| A | HEC503 |
| A | HEC505 |
| A | HOH647 |
| A | HOH663 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue HEC A 505 |
| Chain | Residue |
| A | VAL289 |
| A | HIS290 |
| A | ALA293 |
| A | CYS300 |
| A | PRO320 |
| A | GLY327 |
| A | CYS328 |
| A | CYS331 |
| A | HIS332 |
| A | VAL343 |
| A | HEC504 |
| B | HIS332 |
| B | GLU334 |
| B | TRP338 |
| B | HEC505 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 506 |
| Chain | Residue |
| A | HEC501 |
| A | HOH625 |
| A | HOH695 |
| A | PHE98 |
| A | ARG122 |
| A | TYR221 |
| A | ARG277 |
| A | HIS278 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 506 |
| Chain | Residue |
| B | PHE98 |
| B | ARG122 |
| B | TYR221 |
| B | ARG277 |
| B | HIS278 |
| B | HEC501 |
| B | HOH603 |
| B | HOH660 |
| B | HOH699 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 506 |
| Chain | Residue |
| C | PHE98 |
| C | ARG122 |
| C | TYR221 |
| C | ARG277 |
| C | HIS278 |
| C | HEC501 |
| C | HOH630 |
| C | HOH648 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 506 |
| Chain | Residue |
| D | PHE98 |
| D | ARG122 |
| D | TYR221 |
| D | ARG277 |
| D | HIS278 |
| D | HEC501 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 E 506 |
| Chain | Residue |
| E | PHE98 |
| E | ARG122 |
| E | TYR221 |
| E | ARG277 |
| E | HIS278 |
| E | HEC501 |
| E | HOH619 |
| E | HOH638 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 F 506 |
| Chain | Residue |
| F | PHE98 |
| F | ARG122 |
| F | TYR221 |
| F | ARG277 |
| F | HIS278 |
| F | HEC501 |
| site_id | AD3 |
| Number of Residues | 25 |
| Details | binding site for Di-peptide HEC B 501 and CYS B 129 |
| Chain | Residue |
| B | TYR102 |
| B | ASN103 |
| B | PRO105 |
| B | GLN115 |
| B | ILE118 |
| B | ARG122 |
| B | GLY126 |
| B | GLY127 |
| B | ALA128 |
| B | LEU130 |
| B | THR131 |
| B | CYS132 |
| B | LYS133 |
| B | CYS217 |
| B | HIS218 |
| B | TYR221 |
| B | HIS278 |
| B | ASN407 |
| B | HEC503 |
| B | SO4506 |
| B | HOH602 |
| B | HOH628 |
| B | HOH652 |
| B | HOH660 |
| B | HOH703 |
| site_id | AD4 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide HEC B 501 and CYS B 132 |
| Chain | Residue |
| B | TYR102 |
| B | ASN103 |
| B | PRO105 |
| B | GLN115 |
| B | ILE118 |
| B | ARG122 |
| B | CYS129 |
| B | LEU130 |
| B | THR131 |
| B | LYS133 |
| B | CYS217 |
| B | HIS218 |
| B | TYR221 |
| B | HIS278 |
| B | ASN407 |
| B | HEC503 |
| B | SO4506 |
| B | HOH602 |
| B | HOH628 |
| B | HOH652 |
| B | HOH660 |
| B | HOH703 |
| site_id | AD5 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide HEC B 502 and CYS B 171 |
| Chain | Residue |
| B | TRP45 |
| B | TYR49 |
| B | GLU52 |
| B | TRP56 |
| B | ALA170 |
| B | ILE172 |
| B | ASP173 |
| B | CYS174 |
| B | HIS175 |
| B | MET180 |
| B | LEU182 |
| B | ASN206 |
| B | ARG210 |
| B | MET302 |
| B | LYS311 |
| B | ILE312 |
| B | SER313 |
| B | HIS315 |
| B | HOH676 |
| site_id | AD6 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide HEC B 502 and CYS B 174 |
| Chain | Residue |
| B | TYR49 |
| B | GLU52 |
| B | TRP56 |
| B | ALA170 |
| B | CYS171 |
| B | ILE172 |
| B | ASP173 |
| B | HIS175 |
| B | MET180 |
| B | LEU182 |
| B | LYS183 |
| B | ASN206 |
| B | ARG210 |
| B | MET302 |
| B | LYS311 |
| B | ILE312 |
| B | SER313 |
| B | HIS315 |
| B | HOH676 |
| site_id | AD7 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEC B 503 and CYS B 214 |
| Chain | Residue |
| B | PRO105 |
| B | ARG106 |
| B | HIS108 |
| B | TYR110 |
| B | MET111 |
| B | ASP114 |
| B | CYS132 |
| B | LYS133 |
| B | SER211 |
| B | LEU212 |
| B | VAL213 |
| B | ALA215 |
| B | GLN216 |
| B | CYS217 |
| B | HIS218 |
| B | HIS301 |
| B | MET302 |
| B | ILE317 |
| B | HEC501 |
| B | HEC504 |
| B | HOH657 |
| B | HOH681 |
| B | HOH739 |
| site_id | AD8 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEC B 503 and CYS B 217 |
| Chain | Residue |
| B | PRO105 |
| B | ARG106 |
| B | HIS108 |
| B | TYR110 |
| B | MET111 |
| B | ASP114 |
| B | CYS132 |
| B | LYS133 |
| B | VAL213 |
| B | CYS214 |
| B | ALA215 |
| B | GLN216 |
| B | HIS218 |
| B | VAL219 |
| B | HIS278 |
| B | HIS301 |
| B | MET302 |
| B | ILE317 |
| B | HEC501 |
| B | HEC504 |
| B | HOH657 |
| B | HOH681 |
| B | HOH739 |
| site_id | AD9 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide HEC B 504 and CYS B 297 |
| Chain | Residue |
| B | SER68 |
| B | LYS71 |
| B | PRO105 |
| B | ARG210 |
| B | SER211 |
| B | HIS218 |
| B | TYR284 |
| B | HIS290 |
| B | SER296 |
| B | ALA298 |
| B | ASP299 |
| B | CYS300 |
| B | HIS301 |
| B | SER319 |
| B | GLN347 |
| B | ASN407 |
| B | PHE411 |
| B | HIS412 |
| B | HEC503 |
| B | HEC505 |
| B | HOH614 |
| B | HOH730 |
| site_id | AE1 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC B 504 and CYS B 300 |
| Chain | Residue |
| B | SER68 |
| B | LYS71 |
| B | PRO105 |
| B | HIS218 |
| B | TYR284 |
| B | HIS290 |
| B | SER296 |
| B | CYS297 |
| B | ALA298 |
| B | ASP299 |
| B | HIS301 |
| B | MET302 |
| B | SER319 |
| B | GLN347 |
| B | ASN407 |
| B | PHE411 |
| B | HIS412 |
| B | HEC503 |
| B | HEC505 |
| B | HOH614 |
| B | HOH730 |
| site_id | AE2 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide HEC B 505 and CYS B 328 |
| Chain | Residue |
| A | HIS332 |
| A | GLU334 |
| A | HEC505 |
| B | HIS290 |
| B | ALA293 |
| B | CYS300 |
| B | PHE325 |
| B | LYS326 |
| B | GLY327 |
| B | LYS329 |
| B | GLN330 |
| B | CYS331 |
| B | HIS332 |
| B | LEU339 |
| B | VAL343 |
| B | ALA377 |
| B | HEC504 |
| B | HOH668 |
| B | HOH710 |
| site_id | AE3 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide HEC B 505 and CYS B 331 |
| Chain | Residue |
| A | HIS332 |
| A | GLU334 |
| A | HEC505 |
| B | HIS290 |
| B | ALA293 |
| B | CYS300 |
| B | GLY327 |
| B | CYS328 |
| B | LYS329 |
| B | GLN330 |
| B | HIS332 |
| B | LEU339 |
| B | VAL343 |
| B | ALA377 |
| B | HEC504 |
| B | HOH668 |
| B | HOH710 |
| site_id | AE4 |
| Number of Residues | 24 |
| Details | binding site for Di-peptide HEC C 501 and CYS C 129 |
| Chain | Residue |
| C | TYR102 |
| C | ASN103 |
| C | GLN115 |
| C | ILE118 |
| C | ARG122 |
| C | GLY126 |
| C | GLY127 |
| C | ALA128 |
| C | LEU130 |
| C | THR131 |
| C | CYS132 |
| C | LYS133 |
| C | CYS217 |
| C | HIS218 |
| C | TYR221 |
| C | HIS278 |
| C | ASN407 |
| C | HEC503 |
| C | SO4506 |
| C | HOH610 |
| C | HOH617 |
| C | HOH630 |
| C | HOH655 |
| C | HOH663 |
| site_id | AE5 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC C 501 and CYS C 132 |
| Chain | Residue |
| C | TYR102 |
| C | ASN103 |
| C | GLN115 |
| C | ILE118 |
| C | ARG122 |
| C | CYS129 |
| C | LEU130 |
| C | THR131 |
| C | LYS133 |
| C | CYS217 |
| C | HIS218 |
| C | TYR221 |
| C | HIS278 |
| C | ASN407 |
| C | HEC503 |
| C | SO4506 |
| C | HOH610 |
| C | HOH617 |
| C | HOH630 |
| C | HOH655 |
| C | HOH663 |
| site_id | AE6 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide HEC C 502 and CYS C 171 |
| Chain | Residue |
| C | TRP45 |
| C | TYR49 |
| C | GLU52 |
| C | TYR53 |
| C | TRP56 |
| C | ALA170 |
| C | ILE172 |
| C | ASP173 |
| C | CYS174 |
| C | HIS175 |
| C | LEU182 |
| C | ASN206 |
| C | ARG210 |
| C | MET302 |
| C | LYS311 |
| C | ILE312 |
| C | SER313 |
| C | HIS315 |
| site_id | AE7 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide HEC C 502 and CYS C 174 |
| Chain | Residue |
| C | TYR49 |
| C | GLU52 |
| C | TYR53 |
| C | TRP56 |
| C | ALA170 |
| C | CYS171 |
| C | ILE172 |
| C | ASP173 |
| C | HIS175 |
| C | LEU182 |
| C | LYS183 |
| C | ASN206 |
| C | ARG210 |
| C | MET302 |
| C | LYS311 |
| C | ILE312 |
| C | SER313 |
| C | HIS315 |
| site_id | AE8 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEC C 503 and CYS C 214 |
| Chain | Residue |
| C | PRO105 |
| C | ARG106 |
| C | GLY107 |
| C | HIS108 |
| C | TYR110 |
| C | MET111 |
| C | ASP114 |
| C | CYS132 |
| C | SER211 |
| C | LEU212 |
| C | VAL213 |
| C | ALA215 |
| C | GLN216 |
| C | CYS217 |
| C | HIS218 |
| C | CYS297 |
| C | HIS301 |
| C | ILE317 |
| C | HEC501 |
| C | HEC504 |
| C | HOH611 |
| C | HOH629 |
| C | HOH666 |
| site_id | AE9 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide HEC C 503 and CYS C 217 |
| Chain | Residue |
| C | PRO105 |
| C | ARG106 |
| C | GLY107 |
| C | HIS108 |
| C | TYR110 |
| C | MET111 |
| C | ASP114 |
| C | CYS132 |
| C | VAL213 |
| C | CYS214 |
| C | ALA215 |
| C | GLN216 |
| C | HIS218 |
| C | VAL219 |
| C | HIS278 |
| C | HIS301 |
| C | ILE317 |
| C | HEC501 |
| C | HEC504 |
| C | HOH611 |
| C | HOH629 |
| C | HOH666 |
| site_id | AF1 |
| Number of Residues | 25 |
| Details | binding site for Di-peptide HEC C 504 and CYS C 297 |
| Chain | Residue |
| C | SER68 |
| C | LYS71 |
| C | PRO105 |
| C | ARG210 |
| C | SER211 |
| C | CYS214 |
| C | HIS218 |
| C | GLU280 |
| C | TYR284 |
| C | HIS290 |
| C | SER296 |
| C | ALA298 |
| C | ASP299 |
| C | CYS300 |
| C | HIS301 |
| C | SER319 |
| C | PRO320 |
| C | GLN347 |
| C | ASN407 |
| C | PHE411 |
| C | HIS412 |
| C | HEC503 |
| C | HEC505 |
| C | HOH644 |
| C | HOH651 |
| site_id | AF2 |
| Number of Residues | 24 |
| Details | binding site for Di-peptide HEC C 504 and CYS C 300 |
| Chain | Residue |
| C | SER68 |
| C | LYS71 |
| C | PRO105 |
| C | HIS218 |
| C | GLU280 |
| C | TYR284 |
| C | HIS290 |
| C | SER296 |
| C | CYS297 |
| C | ALA298 |
| C | ASP299 |
| C | HIS301 |
| C | MET302 |
| C | SER319 |
| C | PRO320 |
| C | GLN347 |
| C | ASN407 |
| C | PHE411 |
| C | HIS412 |
| C | HEC503 |
| C | HEC505 |
| C | HOH612 |
| C | HOH644 |
| C | HOH651 |
| site_id | AF3 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide HEC C 505 and CYS C 328 |
| Chain | Residue |
| C | VAL289 |
| C | HIS290 |
| C | ALA293 |
| C | CYS300 |
| C | PRO320 |
| C | PHE325 |
| C | LYS326 |
| C | GLY327 |
| C | LYS329 |
| C | GLN330 |
| C | CYS331 |
| C | HIS332 |
| C | GLN342 |
| C | VAL343 |
| C | HEC504 |
| D | HIS332 |
| D | GLU334 |
| D | HEC505 |
| site_id | AF4 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide HEC C 505 and CYS C 331 |
| Chain | Residue |
| C | VAL289 |
| C | HIS290 |
| C | ALA293 |
| C | CYS300 |
| C | PRO320 |
| C | GLY327 |
| C | CYS328 |
| C | LYS329 |
| C | GLN330 |
| C | HIS332 |
| C | GLN342 |
| C | VAL343 |
| C | HEC504 |
| C | HOH688 |
| D | HIS332 |
| D | GLU334 |
| D | HEC505 |
| site_id | AF5 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide HEC D 501 and CYS D 132 |
| Chain | Residue |
| D | TYR102 |
| D | ASN103 |
| D | PRO105 |
| D | GLN115 |
| D | ARG122 |
| D | CYS129 |
| D | LEU130 |
| D | THR131 |
| D | LYS133 |
| D | CYS217 |
| D | HIS218 |
| D | TYR221 |
| D | HIS278 |
| D | ASN407 |
| D | HEC503 |
| D | SO4506 |
| D | HOH645 |
| site_id | AF6 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide HEC D 501 and CYS D 129 |
| Chain | Residue |
| D | TYR102 |
| D | ASN103 |
| D | PRO105 |
| D | GLN115 |
| D | ARG122 |
| D | GLY126 |
| D | GLY127 |
| D | ALA128 |
| D | LEU130 |
| D | THR131 |
| D | CYS132 |
| D | LYS133 |
| D | CYS217 |
| D | HIS218 |
| D | TYR221 |
| D | HIS278 |
| D | ASN407 |
| D | HEC503 |
| D | SO4506 |
| D | HOH645 |
| site_id | AF7 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide HEC D 502 and CYS D 174 |
| Chain | Residue |
| D | TYR49 |
| D | GLU52 |
| D | TYR53 |
| D | TRP56 |
| D | ALA170 |
| D | CYS171 |
| D | ILE172 |
| D | ASP173 |
| D | HIS175 |
| D | MET180 |
| D | LEU182 |
| D | LYS183 |
| D | ASN206 |
| D | ARG210 |
| D | MET302 |
| D | LYS311 |
| D | ILE312 |
| D | SER313 |
| D | HIS315 |
| D | HOH691 |
| site_id | AF8 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide HEC D 502 and CYS D 171 |
| Chain | Residue |
| D | TRP45 |
| D | TYR49 |
| D | GLU52 |
| D | TYR53 |
| D | TRP56 |
| D | ALA170 |
| D | ILE172 |
| D | ASP173 |
| D | CYS174 |
| D | HIS175 |
| D | MET180 |
| D | LEU182 |
| D | ASN206 |
| D | ARG210 |
| D | MET302 |
| D | LYS311 |
| D | ILE312 |
| D | SER313 |
| D | HIS315 |
| D | HOH691 |
| site_id | AF9 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC D 503 and CYS D 217 |
| Chain | Residue |
| D | PRO105 |
| D | ARG106 |
| D | GLY107 |
| D | HIS108 |
| D | TYR110 |
| D | MET111 |
| D | ASP114 |
| D | CYS132 |
| D | VAL213 |
| D | CYS214 |
| D | ALA215 |
| D | GLN216 |
| D | HIS218 |
| D | VAL219 |
| D | HIS301 |
| D | MET302 |
| D | ILE317 |
| D | MET318 |
| D | HEC501 |
| D | HEC504 |
| D | HOH663 |
| site_id | AG1 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEC D 503 and CYS D 214 |
| Chain | Residue |
| D | PRO105 |
| D | ARG106 |
| D | GLY107 |
| D | HIS108 |
| D | TYR110 |
| D | MET111 |
| D | ASP114 |
| D | CYS132 |
| D | SER211 |
| D | LEU212 |
| D | VAL213 |
| D | ALA215 |
| D | GLN216 |
| D | CYS217 |
| D | HIS218 |
| D | CYS297 |
| D | HIS301 |
| D | MET302 |
| D | ILE317 |
| D | MET318 |
| D | HEC501 |
| D | HEC504 |
| D | HOH663 |
| site_id | AG2 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC D 504 and CYS D 297 |
| Chain | Residue |
| D | SER68 |
| D | LYS71 |
| D | SER211 |
| D | CYS214 |
| D | HIS218 |
| D | GLU280 |
| D | TYR284 |
| D | HIS290 |
| D | VAL295 |
| D | SER296 |
| D | ALA298 |
| D | ASP299 |
| D | CYS300 |
| D | HIS301 |
| D | SER319 |
| D | GLN347 |
| D | ASN407 |
| D | PHE411 |
| D | HIS412 |
| D | HEC503 |
| D | HOH639 |
| site_id | AG3 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide HEC D 505 and CYS D 328 |
| Chain | Residue |
| C | HIS332 |
| C | GLU334 |
| C | HEC505 |
| D | VAL289 |
| D | HIS290 |
| D | ALA293 |
| D | VAL295 |
| D | ASP299 |
| D | CYS300 |
| D | PRO320 |
| D | PHE325 |
| D | LYS326 |
| D | GLY327 |
| D | LYS329 |
| D | GLN330 |
| D | CYS331 |
| D | HIS332 |
| D | GLN342 |
| D | VAL343 |
| D | ILE346 |
| site_id | AG4 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide HEC E 501 and CYS E 132 |
| Chain | Residue |
| E | TYR102 |
| E | ASN103 |
| E | PRO105 |
| E | GLN115 |
| E | ARG122 |
| E | CYS129 |
| E | LEU130 |
| E | THR131 |
| E | LYS133 |
| E | CYS217 |
| E | HIS218 |
| E | TYR221 |
| E | ILE223 |
| E | PHE236 |
| E | HIS278 |
| E | ASN407 |
| E | HEC503 |
| E | SO4506 |
| E | HOH606 |
| E | HOH633 |
| E | HOH638 |
| E | HOH642 |
| site_id | AG5 |
| Number of Residues | 25 |
| Details | binding site for Di-peptide HEC E 501 and CYS E 129 |
| Chain | Residue |
| E | TYR102 |
| E | ASN103 |
| E | PRO105 |
| E | GLN115 |
| E | ARG122 |
| E | GLY126 |
| E | GLY127 |
| E | ALA128 |
| E | LEU130 |
| E | THR131 |
| E | CYS132 |
| E | LYS133 |
| E | CYS217 |
| E | HIS218 |
| E | TYR221 |
| E | ILE223 |
| E | PHE236 |
| E | HIS278 |
| E | ASN407 |
| E | HEC503 |
| E | SO4506 |
| E | HOH606 |
| E | HOH633 |
| E | HOH638 |
| E | HOH642 |
| site_id | AG6 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC E 502 and CYS E 174 |
| Chain | Residue |
| E | TYR49 |
| E | GLU52 |
| E | TYR53 |
| E | TRP56 |
| E | VAL169 |
| E | ALA170 |
| E | CYS171 |
| E | ILE172 |
| E | ASP173 |
| E | HIS175 |
| E | MET180 |
| E | GLY181 |
| E | LEU182 |
| E | LYS183 |
| E | ASN206 |
| E | ARG210 |
| E | MET302 |
| E | LYS311 |
| E | ILE312 |
| E | SER313 |
| E | HIS315 |
| site_id | AG7 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC E 502 and CYS E 171 |
| Chain | Residue |
| E | TRP45 |
| E | TYR49 |
| E | GLU52 |
| E | TYR53 |
| E | TRP56 |
| E | VAL169 |
| E | ALA170 |
| E | ILE172 |
| E | ASP173 |
| E | CYS174 |
| E | HIS175 |
| E | MET180 |
| E | LEU182 |
| E | ASN206 |
| E | ARG210 |
| E | MET302 |
| E | LYS311 |
| E | ILE312 |
| E | SER313 |
| E | HIS315 |
| E | HOH657 |
| site_id | AG8 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC E 503 and CYS E 217 |
| Chain | Residue |
| E | PRO105 |
| E | ARG106 |
| E | GLY107 |
| E | HIS108 |
| E | TYR110 |
| E | MET111 |
| E | ASP114 |
| E | CYS132 |
| E | LYS133 |
| E | VAL213 |
| E | CYS214 |
| E | ALA215 |
| E | GLN216 |
| E | HIS218 |
| E | VAL219 |
| E | HIS301 |
| E | MET302 |
| E | ILE317 |
| E | HEC501 |
| E | HEC504 |
| E | HOH617 |
| site_id | AG9 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEC E 503 and CYS E 214 |
| Chain | Residue |
| E | PRO105 |
| E | ARG106 |
| E | GLY107 |
| E | HIS108 |
| E | TYR110 |
| E | MET111 |
| E | ASP114 |
| E | CYS132 |
| E | LYS133 |
| E | SER211 |
| E | LEU212 |
| E | VAL213 |
| E | ALA215 |
| E | GLN216 |
| E | CYS217 |
| E | HIS218 |
| E | CYS297 |
| E | HIS301 |
| E | MET302 |
| E | ILE317 |
| E | HEC501 |
| E | HEC504 |
| E | HOH617 |
| site_id | AH1 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEC E 504 and CYS E 300 |
| Chain | Residue |
| E | SER68 |
| E | LYS71 |
| E | PRO105 |
| E | HIS218 |
| E | GLU280 |
| E | TYR284 |
| E | HIS290 |
| E | VAL295 |
| E | SER296 |
| E | CYS297 |
| E | ALA298 |
| E | ASP299 |
| E | HIS301 |
| E | MET302 |
| E | SER319 |
| E | LEU321 |
| E | GLN347 |
| E | ASN407 |
| E | PHE411 |
| E | HIS412 |
| E | HEC503 |
| E | HEC505 |
| E | HOH648 |
| site_id | AH2 |
| Number of Residues | 25 |
| Details | binding site for Di-peptide HEC E 504 and CYS E 297 |
| Chain | Residue |
| E | SER68 |
| E | LYS71 |
| E | PRO105 |
| E | ARG210 |
| E | SER211 |
| E | CYS214 |
| E | HIS218 |
| E | GLU280 |
| E | TYR284 |
| E | HIS290 |
| E | VAL295 |
| E | SER296 |
| E | ALA298 |
| E | ASP299 |
| E | CYS300 |
| E | HIS301 |
| E | SER319 |
| E | LEU321 |
| E | GLN347 |
| E | ASN407 |
| E | PHE411 |
| E | HIS412 |
| E | HEC503 |
| E | HEC505 |
| E | HOH648 |
| site_id | AH3 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide HEC E 505 and CYS E 331 |
| Chain | Residue |
| E | VAL289 |
| E | HIS290 |
| E | ALA293 |
| E | CYS300 |
| E | PRO320 |
| E | GLY327 |
| E | CYS328 |
| E | LYS329 |
| E | GLN330 |
| E | HIS332 |
| E | VAL343 |
| E | ILE346 |
| E | PRO414 |
| E | HEC504 |
| E | HOH628 |
| F | HIS332 |
| F | GLU334 |
| F | TRP338 |
| F | HEC505 |
| site_id | AH4 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC E 505 and CYS E 328 |
| Chain | Residue |
| E | VAL289 |
| E | HIS290 |
| E | ALA293 |
| E | CYS300 |
| E | PRO320 |
| E | PHE325 |
| E | LYS326 |
| E | GLY327 |
| E | LYS329 |
| E | GLN330 |
| E | CYS331 |
| E | HIS332 |
| E | VAL343 |
| E | ILE346 |
| E | PRO414 |
| E | HEC504 |
| E | HOH628 |
| F | HIS332 |
| F | GLU334 |
| F | TRP338 |
| F | HEC505 |
| site_id | AH5 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide HEC F 501 and CYS F 132 |
| Chain | Residue |
| F | TYR102 |
| F | ASN103 |
| F | MET111 |
| F | GLN115 |
| F | ARG122 |
| F | CYS129 |
| F | LEU130 |
| F | THR131 |
| F | LYS133 |
| F | CYS217 |
| F | HIS218 |
| F | TYR221 |
| F | ILE223 |
| F | PHE236 |
| F | HIS278 |
| F | ASN407 |
| F | HEC503 |
| F | SO4506 |
| site_id | AH6 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide HEC F 501 and CYS F 129 |
| Chain | Residue |
| F | TYR102 |
| F | ASN103 |
| F | GLN115 |
| F | ARG122 |
| F | GLY126 |
| F | GLY127 |
| F | ALA128 |
| F | LEU130 |
| F | THR131 |
| F | CYS132 |
| F | LYS133 |
| F | CYS217 |
| F | HIS218 |
| F | TYR221 |
| F | ILE223 |
| F | PHE236 |
| F | HIS278 |
| F | ASN407 |
| F | HEC503 |
| F | SO4506 |
| site_id | AH7 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC F 502 and CYS F 174 |
| Chain | Residue |
| F | HIS315 |
| F | HEC503 |
| F | TYR49 |
| F | GLU52 |
| F | TYR53 |
| F | TRP56 |
| F | ALA170 |
| F | CYS171 |
| F | ILE172 |
| F | ASP173 |
| F | HIS175 |
| F | MET180 |
| F | LEU182 |
| F | LYS183 |
| F | ASN206 |
| F | ARG210 |
| F | VAL213 |
| F | MET302 |
| F | LYS311 |
| F | ILE312 |
| F | SER313 |
| site_id | AH8 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC F 502 and CYS F 171 |
| Chain | Residue |
| F | TRP45 |
| F | TYR49 |
| F | GLU52 |
| F | TYR53 |
| F | TRP56 |
| F | ALA170 |
| F | ILE172 |
| F | ASP173 |
| F | CYS174 |
| F | HIS175 |
| F | MET180 |
| F | LEU182 |
| F | ASN206 |
| F | ARG210 |
| F | VAL213 |
| F | MET302 |
| F | LYS311 |
| F | ILE312 |
| F | SER313 |
| F | HIS315 |
| F | HEC503 |
| site_id | AH9 |
| Number of Residues | 25 |
| Details | binding site for Di-peptide HEC F 503 and CYS F 217 |
| Chain | Residue |
| F | THR63 |
| F | PRO105 |
| F | ARG106 |
| F | GLY107 |
| F | HIS108 |
| F | TYR110 |
| F | MET111 |
| F | ASP114 |
| F | CYS132 |
| F | LYS133 |
| F | VAL169 |
| F | VAL213 |
| F | CYS214 |
| F | ALA215 |
| F | GLN216 |
| F | HIS218 |
| F | VAL219 |
| F | HIS278 |
| F | HIS301 |
| F | ILE317 |
| F | HEC501 |
| F | HEC502 |
| F | HEC504 |
| F | HOH614 |
| F | HOH629 |
| site_id | AI1 |
| Number of Residues | 26 |
| Details | binding site for Di-peptide HEC F 503 and CYS F 214 |
| Chain | Residue |
| F | THR63 |
| F | PRO105 |
| F | ARG106 |
| F | GLY107 |
| F | HIS108 |
| F | TYR110 |
| F | MET111 |
| F | ASP114 |
| F | CYS132 |
| F | LYS133 |
| F | VAL169 |
| F | SER211 |
| F | LEU212 |
| F | VAL213 |
| F | ALA215 |
| F | GLN216 |
| F | CYS217 |
| F | HIS218 |
| F | CYS297 |
| F | HIS301 |
| F | ILE317 |
| F | HEC501 |
| F | HEC502 |
| F | HEC504 |
| F | HOH614 |
| F | HOH629 |
| site_id | AI2 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide HEC F 504 and CYS F 300 |
| Chain | Residue |
| F | SER68 |
| F | LYS71 |
| F | PRO105 |
| F | HIS218 |
| F | GLU280 |
| F | TYR284 |
| F | HIS290 |
| F | SER296 |
| F | CYS297 |
| F | ALA298 |
| F | ASP299 |
| F | HIS301 |
| F | MET302 |
| F | SER319 |
| F | GLN347 |
| F | ASN407 |
| F | PHE411 |
| F | HIS412 |
| F | HEC503 |
| F | HEC505 |
| F | HOH614 |
| F | HOH641 |
| site_id | AI3 |
| Number of Residues | 24 |
| Details | binding site for Di-peptide HEC F 504 and CYS F 297 |
| Chain | Residue |
| F | SER68 |
| F | LYS71 |
| F | PRO105 |
| F | ARG210 |
| F | SER211 |
| F | CYS214 |
| F | HIS218 |
| F | GLU280 |
| F | TYR284 |
| F | HIS290 |
| F | SER296 |
| F | ALA298 |
| F | ASP299 |
| F | CYS300 |
| F | HIS301 |
| F | SER319 |
| F | GLN347 |
| F | ASN407 |
| F | PHE411 |
| F | HIS412 |
| F | HEC503 |
| F | HEC505 |
| F | HOH614 |
| F | HOH641 |
| site_id | AI4 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide HEC F 505 and CYS F 331 |
| Chain | Residue |
| D | ALA376 |
| D | ALA377 |
| E | HIS332 |
| E | GLU334 |
| E | HEC505 |
| F | VAL289 |
| F | HIS290 |
| F | ALA293 |
| F | CYS300 |
| F | PRO320 |
| F | GLY327 |
| F | CYS328 |
| F | LYS329 |
| F | GLN330 |
| F | HIS332 |
| F | GLN342 |
| F | VAL343 |
| F | ILE346 |
| F | PHE411 |
| F | HEC504 |
| F | HOH636 |
| site_id | AI5 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEC F 505 and CYS F 328 |
| Chain | Residue |
| D | ALA376 |
| D | ALA377 |
| E | HIS332 |
| E | GLU334 |
| E | HEC505 |
| F | VAL289 |
| F | HIS290 |
| F | ALA293 |
| F | CYS300 |
| F | PRO320 |
| F | PHE325 |
| F | LYS326 |
| F | GLY327 |
| F | LYS329 |
| F | GLN330 |
| F | CYS331 |
| F | HIS332 |
| F | GLN342 |
| F | VAL343 |
| F | ILE346 |
| F | PHE411 |
| F | HEC504 |
| F | HOH636 |
