6UZY

Cryo-EM structure of Xenopus tropicalis pannexin 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0005921	cellular_component	gap junction
A	0006812	biological_process	monoatomic cation transport
A	0015267	molecular_function	channel activity
A	0016020	cellular_component	membrane
A	0032732	biological_process	positive regulation of interleukin-1 production
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
B	0005886	cellular_component	plasma membrane
B	0005921	cellular_component	gap junction
B	0006812	biological_process	monoatomic cation transport
B	0015267	molecular_function	channel activity
B	0016020	cellular_component	membrane
B	0032732	biological_process	positive regulation of interleukin-1 production
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
C	0005886	cellular_component	plasma membrane
C	0005921	cellular_component	gap junction
C	0006812	biological_process	monoatomic cation transport
C	0015267	molecular_function	channel activity
C	0016020	cellular_component	membrane
C	0032732	biological_process	positive regulation of interleukin-1 production
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
D	0005886	cellular_component	plasma membrane
D	0005921	cellular_component	gap junction
D	0006812	biological_process	monoatomic cation transport
D	0015267	molecular_function	channel activity
D	0016020	cellular_component	membrane
D	0032732	biological_process	positive regulation of interleukin-1 production
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042802	molecular_function	identical protein binding
E	0005886	cellular_component	plasma membrane
E	0005921	cellular_component	gap junction
E	0006812	biological_process	monoatomic cation transport
E	0015267	molecular_function	channel activity
E	0016020	cellular_component	membrane
E	0032732	biological_process	positive regulation of interleukin-1 production
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042802	molecular_function	identical protein binding
F	0005886	cellular_component	plasma membrane
F	0005921	cellular_component	gap junction
F	0006812	biological_process	monoatomic cation transport
F	0015267	molecular_function	channel activity
F	0016020	cellular_component	membrane
F	0032732	biological_process	positive regulation of interleukin-1 production
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0042802	molecular_function	identical protein binding
G	0005886	cellular_component	plasma membrane
G	0005921	cellular_component	gap junction
G	0006812	biological_process	monoatomic cation transport
G	0015267	molecular_function	channel activity
G	0016020	cellular_component	membrane
G	0032732	biological_process	positive regulation of interleukin-1 production
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue 6OU A 501

Chain	Residue
A	VAL34
A	LEU37
A	ILE41
A	PHE292
A	TYR295
A	ARG302
G	PHE126
G	THR130

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site_id	AC2
Number of Residues	8
Details	binding site for residue 6OU B 501

Chain	Residue
A	THR130
B	VAL34
B	LEU37
B	ILE41
B	PHE292
B	TYR295
B	ARG302
A	PHE126

---

site_id	AC3
Number of Residues	9
Details	binding site for residue 6OU C 501

Chain	Residue
B	LEU122
B	PHE126
B	THR130
C	VAL34
C	LEU37
C	ILE41
C	PHE292
C	TYR295
C	ARG302

---

site_id	AC4
Number of Residues	8
Details	binding site for residue 6OU D 501

Chain	Residue
C	PHE126
C	THR130
D	VAL34
D	LEU37
D	ILE41
D	PHE292
D	TYR295
D	ARG302

---

site_id	AC5
Number of Residues	8
Details	binding site for residue 6OU E 501

Chain	Residue
D	PHE126
D	THR130
E	VAL34
E	LEU37
E	ILE41
E	PHE292
E	TYR295
E	ARG302

---

site_id	AC6
Number of Residues	8
Details	binding site for residue 6OU F 501

Chain	Residue
E	PHE126
E	THR130
F	VAL34
F	LEU37
F	ILE41
F	PHE292
F	TYR295
F	ARG302

---

site_id	AC7
Number of Residues	1
Details	binding site for residue R16 F 503

Chain	Residue
F	ILE217

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site_id	AC8
Number of Residues	8
Details	binding site for residue 6OU G 1002

Chain	Residue
F	PHE126
F	THR130
G	VAL34
G	LEU37
G	ILE41
G	PHE292
G	TYR295
G	ARG302

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