Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
| C | 0042981 | biological_process | regulation of apoptotic process |
| D | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | GLY64 |
| A | LEU66 |
| A | GLY67 |
| A | ARG88 |
| A | HOH603 |
| B | ARG88 |
| B | HOH326 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | HIS141 |
| A | GLN144 |
| A | HIS145 |
| A | HOH607 |
| A | HOH612 |
| A | HOH615 |
| A | GLN94 |
| A | GLN98 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue C8E A 503 |
| Chain | Residue |
| A | C8E504 |
| B | LBN202 |
| B | C8E203 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue C8E A 504 |
| Chain | Residue |
| A | GLY135 |
| A | ALA139 |
| A | LEU140 |
| A | C8E503 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue C8E A 505 |
| Chain | Residue |
| A | GLU120 |
| A | SER121 |
| A | EDO506 |
| C | ALA104 |
| D | ALA139 |
| D | C8E201 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | GLU120 |
| A | C8E505 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue C8E B 201 |
| Chain | Residue |
| A | ILE123 |
| A | ASN124 |
| A | TRP125 |
| B | ASN86 |
| B | ASP90 |
| B | TYR136 |
| B | C8E205 |
| B | HOH314 |
| C | ASN124 |
| C | ARG127 |
| C | HOH303 |
| D | ASP83 |
| D | ASN86 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue LBN B 202 |
| Chain | Residue |
| A | LEU132 |
| A | TYR136 |
| A | C8E503 |
| B | ASN124 |
| B | TRP125 |
| B | C8E203 |
| B | HOH312 |
| D | HOH324 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue C8E B 203 |
| Chain | Residue |
| A | C8E503 |
| B | LBN202 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 204 |
| Chain | Residue |
| B | GLN94 |
| B | ARG137 |
| B | HIS141 |
| B | GLN144 |
| B | HIS145 |
| B | HOH307 |
| D | ARG87 |
| site_id | AD2 |
| Number of Residues | 17 |
| Details | binding site for residue C8E B 205 |
| Chain | Residue |
| A | GLY122 |
| A | ARG127 |
| A | HOH602 |
| A | HOH638 |
| B | ASP83 |
| B | ASN86 |
| B | ARG87 |
| B | C8E201 |
| B | HOH318 |
| C | ILE123 |
| C | VAL128 |
| C | VAL129 |
| D | ASN86 |
| D | ASP90 |
| D | LEU132 |
| D | TYR136 |
| D | C8E201 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 206 |
| Chain | Residue |
| A | SER69 |
| B | SER69 |
| B | THR70 |
| B | MET71 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 207 |
| Chain | Residue |
| A | SER117 |
| B | GLY67 |
| B | SER68 |
| B | SER69 |
| B | ARG76 |
| B | HOH313 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue C8E C 200 |
| Chain | Residue |
| C | TYR136 |
| C | HOH301 |
| D | ILE123 |
| D | ASN124 |
| D | HOH321 |
| site_id | AD6 |
| Number of Residues | 10 |
| Details | binding site for residue C8E D 201 |
| Chain | Residue |
| C | TYR143 |
| C | HOH314 |
| D | PHE111 |
| A | C8E505 |
| B | C8E205 |
| C | ALA104 |
| C | GLU105 |
| C | ASN106 |
| C | ALA107 |
| C | TYR108 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 D 202 |
| Chain | Residue |
| B | ARG87 |
| B | HOH310 |
| B | HOH319 |
| D | GLN94 |
| D | ARG137 |
| D | HIS141 |
| D | GLN144 |
| D | HIS145 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 19 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFeSGi.NWGRVVALLgFGY |
| Chain | Residue | Details |
| A | LEU118-TYR136 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VgrqLAiIGDDINRR |
| Chain | Residue | Details |
| A | VAL74-ARG88 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 56 |
| Details | Motif: {"description":"BH3"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 76 |
| Details | Motif: {"description":"BH1"} |
