6UX4
MthK N-terminal truncation RCK domain state 2 bound with calcium
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005886 | cellular_component | plasma membrane |
A | 0006813 | biological_process | potassium ion transport |
A | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
A | 0034220 | biological_process | monoatomic ion transmembrane transport |
A | 0042802 | molecular_function | identical protein binding |
A | 0046872 | molecular_function | metal ion binding |
A | 0098655 | biological_process | monoatomic cation transmembrane transport |
B | 0005886 | cellular_component | plasma membrane |
B | 0006813 | biological_process | potassium ion transport |
B | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
B | 0034220 | biological_process | monoatomic ion transmembrane transport |
B | 0042802 | molecular_function | identical protein binding |
B | 0046872 | molecular_function | metal ion binding |
B | 0098655 | biological_process | monoatomic cation transmembrane transport |
C | 0005886 | cellular_component | plasma membrane |
C | 0006813 | biological_process | potassium ion transport |
C | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
C | 0034220 | biological_process | monoatomic ion transmembrane transport |
C | 0042802 | molecular_function | identical protein binding |
C | 0046872 | molecular_function | metal ion binding |
C | 0098655 | biological_process | monoatomic cation transmembrane transport |
D | 0005886 | cellular_component | plasma membrane |
D | 0006813 | biological_process | potassium ion transport |
D | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
D | 0034220 | biological_process | monoatomic ion transmembrane transport |
D | 0042802 | molecular_function | identical protein binding |
D | 0046872 | molecular_function | metal ion binding |
D | 0098655 | biological_process | monoatomic cation transmembrane transport |
E | 0005886 | cellular_component | plasma membrane |
E | 0006813 | biological_process | potassium ion transport |
E | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
E | 0034220 | biological_process | monoatomic ion transmembrane transport |
E | 0042802 | molecular_function | identical protein binding |
E | 0046872 | molecular_function | metal ion binding |
E | 0098655 | biological_process | monoatomic cation transmembrane transport |
F | 0005886 | cellular_component | plasma membrane |
F | 0006813 | biological_process | potassium ion transport |
F | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
F | 0034220 | biological_process | monoatomic ion transmembrane transport |
F | 0042802 | molecular_function | identical protein binding |
F | 0046872 | molecular_function | metal ion binding |
F | 0098655 | biological_process | monoatomic cation transmembrane transport |
G | 0005886 | cellular_component | plasma membrane |
G | 0006813 | biological_process | potassium ion transport |
G | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
G | 0034220 | biological_process | monoatomic ion transmembrane transport |
G | 0042802 | molecular_function | identical protein binding |
G | 0046872 | molecular_function | metal ion binding |
G | 0098655 | biological_process | monoatomic cation transmembrane transport |
H | 0005886 | cellular_component | plasma membrane |
H | 0006813 | biological_process | potassium ion transport |
H | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
H | 0034220 | biological_process | monoatomic ion transmembrane transport |
H | 0042802 | molecular_function | identical protein binding |
H | 0046872 | molecular_function | metal ion binding |
H | 0098655 | biological_process | monoatomic cation transmembrane transport |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue CA A 401 |
Chain | Residue |
A | ASP184 |
A | GLU210 |
A | GLU212 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue CA A 402 |
Chain | Residue |
A | ARG241 |
A | ASP245 |
A | GLU248 |
E | GLU266 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue CA A 403 |
Chain | Residue |
E | ASP305 |
A | GLY290 |
A | GLU326 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue CA A 404 |
Chain | Residue |
A | GLU266 |
E | ARG241 |
E | ASP245 |
E | GLU248 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue CA E 401 |
Chain | Residue |
E | ASP184 |
E | GLU210 |
E | GLU212 |
site_id | AC6 |
Number of Residues | 3 |
Details | binding site for residue CA E 402 |
Chain | Residue |
A | ASP305 |
E | GLY290 |
E | GLU326 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue CA B 401 |
Chain | Residue |
B | SER124 |
B | ASP184 |
B | GLU210 |
B | GLU212 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue CA B 402 |
Chain | Residue |
B | ARG241 |
B | ASP245 |
B | GLU248 |
F | GLU266 |
site_id | AC9 |
Number of Residues | 3 |
Details | binding site for residue CA B 403 |
Chain | Residue |
B | ASP305 |
F | GLY290 |
F | GLU326 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue CA B 404 |
Chain | Residue |
B | GLU266 |
F | ARG241 |
F | ASP245 |
F | GLU248 |
site_id | AD2 |
Number of Residues | 5 |
Details | binding site for residue CA B 405 |
Chain | Residue |
B | HIS286 |
B | GLY290 |
B | GLU326 |
F | ASP305 |
F | ARG308 |
site_id | AD3 |
Number of Residues | 2 |
Details | binding site for residue CA F 401 |
Chain | Residue |
F | ASP184 |
F | GLU210 |
site_id | AD4 |
Number of Residues | 3 |
Details | binding site for residue CA C 401 |
Chain | Residue |
C | ASP184 |
C | GLU210 |
C | GLU212 |
site_id | AD5 |
Number of Residues | 4 |
Details | binding site for residue CA C 402 |
Chain | Residue |
C | ARG241 |
C | ASP245 |
C | GLU248 |
G | GLU266 |
site_id | AD6 |
Number of Residues | 3 |
Details | binding site for residue CA C 403 |
Chain | Residue |
C | GLY290 |
C | GLU326 |
G | ASP305 |
site_id | AD7 |
Number of Residues | 4 |
Details | binding site for residue CA C 404 |
Chain | Residue |
C | GLU266 |
G | ARG241 |
G | ASP245 |
G | GLU248 |
site_id | AD8 |
Number of Residues | 4 |
Details | binding site for residue CA G 401 |
Chain | Residue |
G | SER126 |
G | ASP184 |
G | GLU210 |
G | GLU212 |
site_id | AD9 |
Number of Residues | 3 |
Details | binding site for residue CA G 402 |
Chain | Residue |
C | ASP305 |
G | GLY290 |
G | GLU326 |
site_id | AE1 |
Number of Residues | 4 |
Details | binding site for residue CA D 401 |
Chain | Residue |
D | SER124 |
D | ASP184 |
D | GLU210 |
D | GLU212 |
site_id | AE2 |
Number of Residues | 4 |
Details | binding site for residue CA D 402 |
Chain | Residue |
D | ARG241 |
D | ASP245 |
D | GLU248 |
H | GLU266 |
site_id | AE3 |
Number of Residues | 3 |
Details | binding site for residue CA D 403 |
Chain | Residue |
D | ASP305 |
H | GLY290 |
H | GLU326 |
site_id | AE4 |
Number of Residues | 4 |
Details | binding site for residue CA D 404 |
Chain | Residue |
D | GLU266 |
H | ARG241 |
H | ASP245 |
H | GLU248 |
site_id | AE5 |
Number of Residues | 2 |
Details | binding site for residue CA H 401 |
Chain | Residue |
H | ASP184 |
H | GLU210 |
site_id | AE6 |
Number of Residues | 3 |
Details | binding site for residue CA H 402 |
Chain | Residue |
D | GLY290 |
D | GLU326 |
H | ASP305 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 232 |
Details | TOPO_DOM: Cytoplasmic |
Chain | Residue | Details |
A | MET1-ALA20 | |
C | GLU96-LEU106 | |
G | MET1-ALA20 | |
G | GLU96-LEU106 | |
D | MET1-ALA20 | |
D | GLU96-LEU106 | |
H | MET1-ALA20 | |
H | GLU96-LEU106 | |
A | GLU96-LEU106 | |
E | MET1-ALA20 | |
E | GLU96-LEU106 | |
B | MET1-ALA20 | |
B | GLU96-LEU106 | |
F | MET1-ALA20 | |
F | GLU96-LEU106 | |
C | MET1-ALA20 |
site_id | SWS_FT_FI2 |
Number of Residues | 160 |
Details | TRANSMEM: Helical; Name=Outer helix M1 |
Chain | Residue | Details |
A | THR21-ILE41 | |
E | THR21-ILE41 | |
B | THR21-ILE41 | |
F | THR21-ILE41 | |
C | THR21-ILE41 | |
G | THR21-ILE41 | |
D | THR21-ILE41 | |
H | THR21-ILE41 |
site_id | SWS_FT_FI3 |
Number of Residues | 80 |
Details | TOPO_DOM: Extracellular |
Chain | Residue | Details |
A | GLU42-VAL48 | |
C | TYR65-THR69 | |
G | GLU42-VAL48 | |
G | TYR65-THR69 | |
D | GLU42-VAL48 | |
D | TYR65-THR69 | |
H | GLU42-VAL48 | |
H | TYR65-THR69 | |
A | TYR65-THR69 | |
E | GLU42-VAL48 | |
E | TYR65-THR69 | |
B | GLU42-VAL48 | |
B | TYR65-THR69 | |
F | GLU42-VAL48 | |
F | TYR65-THR69 | |
C | GLU42-VAL48 |
site_id | SWS_FT_FI4 |
Number of Residues | 72 |
Details | INTRAMEM: Helical; Pore-forming => ECO:0000255 |
Chain | Residue | Details |
A | SER49-ALA58 | |
E | SER49-ALA58 | |
B | SER49-ALA58 | |
F | SER49-ALA58 | |
C | SER49-ALA58 | |
G | SER49-ALA58 | |
D | SER49-ALA58 | |
H | SER49-ALA58 |
site_id | SWS_FT_FI5 |
Number of Residues | 40 |
Details | INTRAMEM: Pore-forming => ECO:0000255 |
Chain | Residue | Details |
A | THR59-ASP64 | |
E | THR59-ASP64 | |
B | THR59-ASP64 | |
F | THR59-ASP64 | |
C | THR59-ASP64 | |
G | THR59-ASP64 | |
D | THR59-ASP64 | |
H | THR59-ASP64 |
site_id | SWS_FT_FI6 |
Number of Residues | 200 |
Details | TRANSMEM: Helical; Name=Inner helix M2 |
Chain | Residue | Details |
A | PRO70-LEU95 | |
E | PRO70-LEU95 | |
B | PRO70-LEU95 | |
F | PRO70-LEU95 | |
C | PRO70-LEU95 | |
G | PRO70-LEU95 | |
D | PRO70-LEU95 | |
H | PRO70-LEU95 |
site_id | SWS_FT_FI7 |
Number of Residues | 24 |
Details | BINDING: |
Chain | Residue | Details |
A | ASP184 | |
F | ASP184 | |
F | GLU210 | |
F | GLU212 | |
C | ASP184 | |
C | GLU210 | |
C | GLU212 | |
G | ASP184 | |
G | GLU210 | |
G | GLU212 | |
D | ASP184 | |
A | GLU210 | |
D | GLU210 | |
D | GLU212 | |
H | ASP184 | |
H | GLU210 | |
H | GLU212 | |
A | GLU212 | |
E | ASP184 | |
E | GLU210 | |
E | GLU212 | |
B | ASP184 | |
B | GLU210 | |
B | GLU212 |