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6UWM

Single particle cryo-EM structure of KvAP

Functional Information from GO Data
ChainGOidnamespacecontents
A0001508biological_processaction potential
A0005216molecular_functionmonoatomic ion channel activity
A0005249molecular_functionvoltage-gated potassium channel activity
A0005267molecular_functionpotassium channel activity
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0006813biological_processpotassium ion transport
A0008076cellular_componentvoltage-gated potassium channel complex
A0016020cellular_componentmembrane
A0034220biological_processmonoatomic ion transmembrane transport
A0034702cellular_componentmonoatomic ion channel complex
A0042802molecular_functionidentical protein binding
A0055085biological_processtransmembrane transport
A0071805biological_processpotassium ion transmembrane transport
B0001508biological_processaction potential
B0005216molecular_functionmonoatomic ion channel activity
B0005249molecular_functionvoltage-gated potassium channel activity
B0005267molecular_functionpotassium channel activity
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0006813biological_processpotassium ion transport
B0008076cellular_componentvoltage-gated potassium channel complex
B0016020cellular_componentmembrane
B0034220biological_processmonoatomic ion transmembrane transport
B0034702cellular_componentmonoatomic ion channel complex
B0042802molecular_functionidentical protein binding
B0055085biological_processtransmembrane transport
B0071805biological_processpotassium ion transmembrane transport
C0001508biological_processaction potential
C0005216molecular_functionmonoatomic ion channel activity
C0005249molecular_functionvoltage-gated potassium channel activity
C0005267molecular_functionpotassium channel activity
C0005886cellular_componentplasma membrane
C0006811biological_processmonoatomic ion transport
C0006813biological_processpotassium ion transport
C0008076cellular_componentvoltage-gated potassium channel complex
C0016020cellular_componentmembrane
C0034220biological_processmonoatomic ion transmembrane transport
C0034702cellular_componentmonoatomic ion channel complex
C0042802molecular_functionidentical protein binding
C0055085biological_processtransmembrane transport
C0071805biological_processpotassium ion transmembrane transport
D0001508biological_processaction potential
D0005216molecular_functionmonoatomic ion channel activity
D0005249molecular_functionvoltage-gated potassium channel activity
D0005267molecular_functionpotassium channel activity
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0006813biological_processpotassium ion transport
D0008076cellular_componentvoltage-gated potassium channel complex
D0016020cellular_componentmembrane
D0034220biological_processmonoatomic ion transmembrane transport
D0034702cellular_componentmonoatomic ion channel complex
D0042802molecular_functionidentical protein binding
D0055085biological_processtransmembrane transport
D0071805biological_processpotassium ion transmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues96
DetailsTransmembrane: {"description":"Helical; Name=Segment S1"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues108
DetailsTopological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues96
DetailsTransmembrane: {"description":"Helical; Name=Segment S2"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues72
DetailsTopological domain: {"description":"Cytoplasmic"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues32
DetailsIntramembrane: {"description":"Helical; Name=Segment S3A"}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues64
DetailsTransmembrane: {"description":"Helical; Voltage-sensor; Name=Segment S3B"}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues64
DetailsTransmembrane: {"description":"Helical; Voltage-sensor; Name=Segment S4"}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues96
DetailsTransmembrane: {"description":"Helical; Name=Segment S5"}
ChainResidueDetails

site_idSWS_FT_FI9
Number of Residues48
DetailsIntramembrane: {"description":"Pore-forming","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI10
Number of Residues124
DetailsTransmembrane: {"description":"Helical; Name=Segment S6"}
ChainResidueDetails

site_idSWS_FT_FI11
Number of Residues20
DetailsMotif: {"description":"Selectivity filter"}
ChainResidueDetails

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PDB entries from 2025-08-27

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