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6UWM

Single particle cryo-EM structure of KvAP

Functional Information from GO Data
ChainGOidnamespacecontents
A0001508biological_processaction potential
A0005216molecular_functionmonoatomic ion channel activity
A0005249molecular_functionvoltage-gated potassium channel activity
A0005267molecular_functionpotassium channel activity
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0006813biological_processpotassium ion transport
A0008076cellular_componentvoltage-gated potassium channel complex
A0016020cellular_componentmembrane
A0034702cellular_componentmonoatomic ion channel complex
A0042802molecular_functionidentical protein binding
A0055085biological_processtransmembrane transport
A0071805biological_processpotassium ion transmembrane transport
B0001508biological_processaction potential
B0005216molecular_functionmonoatomic ion channel activity
B0005249molecular_functionvoltage-gated potassium channel activity
B0005267molecular_functionpotassium channel activity
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0006813biological_processpotassium ion transport
B0008076cellular_componentvoltage-gated potassium channel complex
B0016020cellular_componentmembrane
B0034702cellular_componentmonoatomic ion channel complex
B0042802molecular_functionidentical protein binding
B0055085biological_processtransmembrane transport
B0071805biological_processpotassium ion transmembrane transport
C0001508biological_processaction potential
C0005216molecular_functionmonoatomic ion channel activity
C0005249molecular_functionvoltage-gated potassium channel activity
C0005267molecular_functionpotassium channel activity
C0005886cellular_componentplasma membrane
C0006811biological_processmonoatomic ion transport
C0006813biological_processpotassium ion transport
C0008076cellular_componentvoltage-gated potassium channel complex
C0016020cellular_componentmembrane
C0034702cellular_componentmonoatomic ion channel complex
C0042802molecular_functionidentical protein binding
C0055085biological_processtransmembrane transport
C0071805biological_processpotassium ion transmembrane transport
D0001508biological_processaction potential
D0005216molecular_functionmonoatomic ion channel activity
D0005249molecular_functionvoltage-gated potassium channel activity
D0005267molecular_functionpotassium channel activity
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0006813biological_processpotassium ion transport
D0008076cellular_componentvoltage-gated potassium channel complex
D0016020cellular_componentmembrane
D0034702cellular_componentmonoatomic ion channel complex
D0042802molecular_functionidentical protein binding
D0055085biological_processtransmembrane transport
D0071805biological_processpotassium ion transmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues96
DetailsTRANSMEM: Helical; Name=Segment S1
ChainResidueDetails
ALEU26-LEU50
CLEU26-LEU50
BLEU26-LEU50
DLEU26-LEU50

site_idSWS_FT_FI2
Number of Residues108
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
ASER51-TYR54
BGLU93-PRO95
BGLU172-SER182
BTHR196-ILE208
DSER51-TYR54
DGLU93-PRO95
DGLU172-SER182
DTHR196-ILE208
AGLU93-PRO95
AGLU172-SER182
ATHR196-ILE208
CSER51-TYR54
CGLU93-PRO95
CGLU172-SER182
CTHR196-ILE208
BSER51-TYR54

site_idSWS_FT_FI3
Number of Residues96
DetailsTRANSMEM: Helical; Name=Segment S2
ChainResidueDetails
ALEU55-LYS79
CLEU55-LYS79
BLEU55-LYS79
DLEU55-LYS79

site_idSWS_FT_FI4
Number of Residues236
DetailsTOPO_DOM: Cytoplasmic
ChainResidueDetails
ASER80-PRO83
BLEU113-LEU115
BARG133-ASP146
BGLY241-LYS282
DSER80-PRO83
DLEU113-LEU115
DARG133-ASP146
DGLY241-LYS282
ALEU113-LEU115
AARG133-ASP146
AGLY241-LYS282
CSER80-PRO83
CLEU113-LEU115
CARG133-ASP146
CGLY241-LYS282
BSER80-PRO83

site_idSWS_FT_FI5
Number of Residues32
DetailsINTRAMEM: Helical; Name=Segment S3A
ChainResidueDetails
AALA84-TYR92
CALA84-TYR92
BALA84-TYR92
DALA84-TYR92

site_idSWS_FT_FI6
Number of Residues64
DetailsTRANSMEM: Helical; Voltage-sensor; Name=Segment S3B
ChainResidueDetails
AALA96-GLY112
CALA96-GLY112
BALA96-GLY112
DALA96-GLY112

site_idSWS_FT_FI7
Number of Residues64
DetailsTRANSMEM: Helical; Voltage-sensor; Name=Segment S4
ChainResidueDetails
APHE116-SER132
CPHE116-SER132
BPHE116-SER132
DPHE116-SER132

site_idSWS_FT_FI8
Number of Residues96
DetailsTRANSMEM: Helical; Name=Segment S5
ChainResidueDetails
ALYS147-VAL171
CLYS147-VAL171
BLYS147-VAL171
DLYS147-VAL171

site_idSWS_FT_FI9
Number of Residues48
DetailsINTRAMEM: Pore-forming => ECO:0000255
ChainResidueDetails
AVAL183-THR195
CVAL183-THR195
BVAL183-THR195
DVAL183-THR195

site_idSWS_FT_FI10
Number of Residues124
DetailsTRANSMEM: Helical; Name=Segment S6
ChainResidueDetails
AGLY209-VAL240
CGLY209-VAL240
BGLY209-VAL240
DGLY209-VAL240

227344

PDB entries from 2024-11-13

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