Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue XOY A 301 |
| Chain | Residue |
| A | ALA93 |
| A | PHE146 |
| A | PHE191 |
| A | EDO308 |
| A | HOH415 |
| A | HOH481 |
| A | HOH516 |
| A | TYR101 |
| A | ALA104 |
| A | PHE105 |
| A | LEU108 |
| A | GLU129 |
| A | TRP137 |
| A | GLY138 |
| A | ALA142 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | TYR22 |
| A | SER23 |
| A | HOH440 |
| B | VAL155 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ARG100 |
| A | GLN160 |
| A | VAL161 |
| A | HOH433 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | GLN125 |
| A | ASN128 |
| A | HOH444 |
| B | GLU96 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | TRP24 |
| A | SER25 |
| A | EDO309 |
| A | HOH412 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | TYR101 |
| A | ARG103 |
| A | ALA104 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | GLY134 |
| A | VAL135 |
| A | TRP181 |
| A | HOH483 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | LEU130 |
| A | ARG139 |
| A | XOY301 |
| A | HOH415 |
| A | HOH442 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | SER14 |
| A | MET83 |
| A | ALA84 |
| A | LYS87 |
| A | EDO305 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | GLN160 |
| A | HOH411 |
| B | TRP24 |
| site_id | AD2 |
| Number of Residues | 12 |
| Details | binding site for residue XOY B 301 |
| Chain | Residue |
| B | ALA93 |
| B | TYR101 |
| B | PHE105 |
| B | LEU108 |
| B | ASN136 |
| B | TRP137 |
| B | GLY138 |
| B | ARG139 |
| B | ALA142 |
| B | PHE191 |
| B | EDO304 |
| B | HOH410 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | THR115 |
| B | GLY117 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| A | ARG6 |
| A | VAL10 |
| B | ALA167 |
| B | ALA168 |
| B | HOH403 |
| B | HOH408 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | ARG139 |
| B | XOY301 |
| B | HOH410 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 19 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG |
| Chain | Residue | Details |
| A | LEU130-GLY148 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV |
| Chain | Residue | Details |
| A | TRP181-VAL192 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR |
| Chain | Residue | Details |
| A | VAL86-ARG100 | |
| site_id | PS01260 |
| Number of Residues | 21 |
| Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW |
| Chain | Residue | Details |
| A | SER4-TRP24 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by caspase-1 |
| Chain | Residue | Details |
| A | GLY117 | |
| B | GLY117 | |
| Chain | Residue | Details |
| A | PHE105 | |
| B | PHE105 | |
| Chain | Residue | Details |
| A | THR118 | |
| B | THR118 | |
