6UT5

Cryo-EM structure of the Thermococcus gammatolerans McrBC complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004519	molecular_function	endonuclease activity
A	0005524	molecular_function	ATP binding
A	0016887	molecular_function	ATP hydrolysis activity
A	0046872	molecular_function	metal ion binding
B	0004519	molecular_function	endonuclease activity
B	0005524	molecular_function	ATP binding
B	0016887	molecular_function	ATP hydrolysis activity
B	0046872	molecular_function	metal ion binding
C	0004519	molecular_function	endonuclease activity
C	0005524	molecular_function	ATP binding
C	0016887	molecular_function	ATP hydrolysis activity
C	0046872	molecular_function	metal ion binding
D	0004519	molecular_function	endonuclease activity
D	0005524	molecular_function	ATP binding
D	0016887	molecular_function	ATP hydrolysis activity
D	0046872	molecular_function	metal ion binding
E	0004519	molecular_function	endonuclease activity
E	0005524	molecular_function	ATP binding
E	0016887	molecular_function	ATP hydrolysis activity
E	0046872	molecular_function	metal ion binding
F	0004519	molecular_function	endonuclease activity
F	0005524	molecular_function	ATP binding
F	0016887	molecular_function	ATP hydrolysis activity
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue GSP A 701

Chain	Residue
A	PRO217
A	HIS501
A	SER502
A	LEU505
A	MG702
A	HOH801
A	HOH802
B	ARG425
A	GLY218
A	THR219
A	GLY220
A	LYS221
A	THR222
A	TRP223
A	PHE438
A	ILE447

---

site_id	AC2
Number of Residues	7
Details	binding site for residue MG A 702

Chain	Residue
A	THR222
A	ASP356
A	GLU357
A	THR408
A	GSP701
A	HOH801
A	HOH802

---

site_id	AC3
Number of Residues	25
Details	binding site for residue GSP B 701

Chain	Residue
B	PRO217
B	GLY218
B	THR219
B	GLY220
B	LYS221
B	THR222
B	TRP223
B	PHE438
B	ILE447
B	LYS451
B	HIS501
B	SER502
B	LEU505
B	MG702
B	HOH801
B	HOH802
B	HOH803
B	HOH804
C	GLU375
C	ASP377
C	LYS378
C	ASN384
C	ALA422
C	ARG425
C	ARG426

---

site_id	AC4
Number of Residues	7
Details	binding site for residue MG B 702

Chain	Residue
B	THR222
B	ASP356
B	GLU357
B	THR408
B	GSP701
B	HOH801
B	HOH804

---

site_id	AC5
Number of Residues	23
Details	binding site for residue GSP C 701

Chain	Residue
C	PRO217
C	GLY218
C	THR219
C	GLY220
C	LYS221
C	THR222
C	TRP223
C	GLU357
C	PHE438
C	ILE447
C	HIS501
C	SER502
C	LEU505
C	MG702
C	HOH901
C	HOH903
C	HOH905
D	GLU375
D	ASP377
D	LYS378
D	ASN384
D	ARG425
D	ARG426

---

site_id	AC6
Number of Residues	7
Details	binding site for residue MG C 702

Chain	Residue
C	THR222
C	ASP356
C	GLU357
C	GSP701
C	HOH901
C	HOH905
D	ARG426

---

site_id	AC7
Number of Residues	28
Details	binding site for residue GSP D 701

Chain	Residue
D	LEU505
D	MG702
D	HOH802
D	HOH803
D	HOH805
D	HOH806
D	HOH807
E	GLU375
E	ASP377
E	LYS378
E	ASN384
E	ALA422
E	ARG425
E	ARG426
D	ASN193
D	PRO217
D	GLY218
D	THR219
D	GLY220
D	LYS221
D	THR222
D	TRP223
D	GLU357
D	ASN410
D	PHE438
D	ILE447
D	HIS501
D	SER502

---

site_id	AC8
Number of Residues	7
Details	binding site for residue MG D 702

Chain	Residue
D	THR222
D	ASP356
D	GLU357
D	GSP701
D	HOH803
D	HOH805
D	HOH807

---

site_id	AC9
Number of Residues	28
Details	binding site for residue GSP E 701

Chain	Residue
E	ASN193
E	PRO217
E	GLY218
E	THR219
E	GLY220
E	LYS221
E	THR222
E	TRP223
E	GLU357
E	ASN410
E	PHE438
E	ILE447
E	LYS450
E	HIS501
E	SER502
E	LEU505
E	MG702
E	HOH801
E	HOH803
E	HOH804
E	HOH805
E	HOH806
F	GLU375
F	ASP377
F	LYS378
F	ASN384
F	ARG425
F	ARG426

---

site_id	AD1
Number of Residues	8
Details	binding site for residue MG E 702

Chain	Residue
E	THR222
E	ASP356
E	GLU357
E	GSP701
E	HOH801
E	HOH803
E	HOH804
F	ARG426

---

site_id	AD2
Number of Residues	16
Details	binding site for residue GDP F 701

Chain	Residue
A	ASP377
F	PRO217
F	GLY218
F	THR219
F	GLY220
F	LYS221
F	THR222
F	TRP223
F	ASN410
F	ILE447
F	LYS450
F	HIS501
F	SER502
F	LEU505
F	MG702
F	HOH802

---

site_id	AD3
Number of Residues	6
Details	binding site for residue MG F 702

Chain	Residue
F	THR222
F	ASP356
F	GLU357
F	GDP701
F	HOH802
F	HOH803

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