6UR9

DNA polymerase I Large Fragment from Bacillus stearothermophilus with DNA template, dideoxy primer, 3'-amino-ddGTP (nGTP), and Ca2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0004518	molecular_function	nuclease activity
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006302	biological_process	double-strand break repair
A	0006974	biological_process	DNA damage response
A	0008408	molecular_function	3'-5' exonuclease activity
A	0046872	molecular_function	metal ion binding
A	0071897	biological_process	DNA biosynthetic process
D	0000166	molecular_function	nucleotide binding
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0004518	molecular_function	nuclease activity
D	0006139	biological_process	nucleobase-containing compound metabolic process
D	0006260	biological_process	DNA replication
D	0006261	biological_process	DNA-templated DNA replication
D	0006281	biological_process	DNA repair
D	0006302	biological_process	double-strand break repair
D	0006974	biological_process	DNA damage response
D	0008408	molecular_function	3'-5' exonuclease activity
D	0046872	molecular_function	metal ion binding
D	0071897	biological_process	DNA biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue NG3 A 901

Chain	Residue
A	ASP653
A	TYR714
A	ASP830
A	CA902
A	HOH1006
A	HOH1074
B	DOC9
C	DC3
C	DG4
A	TYR654
A	GLN656
A	ILE657
A	GLU658
A	HIS682
A	ARG702
A	LYS706
A	TYR710

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site_id	AC2
Number of Residues	4
Details	binding site for residue CA A 902

Chain	Residue
A	ASP653
A	TYR654
A	ASP830
A	NG3901

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site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 903

Chain	Residue
A	MET299
A	ALA300
A	ARG343
A	ARG677

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site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 904

Chain	Residue
A	GLU321
A	VAL322
A	ASP425

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site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 A 905

Chain	Residue
A	LYS383
D	GLU501
D	PRO597
D	HOH1020

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site_id	AC6
Number of Residues	3
Details	binding site for residue SO4 A 906

Chain	Residue
D	LYS498
D	HOH1021
D	HOH1035

---

site_id	AC7
Number of Residues	4
Details	binding site for residue SO4 A 907

Chain	Residue
A	ARG423
A	PRO424
D	ARG779
D	ASN780

---

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 A 908

Chain	Residue
A	PRO597
A	HOH1012
D	LYS383

---

site_id	AC9
Number of Residues	4
Details	binding site for residue SO4 A 909

Chain	Residue
A	ARG306
A	THR308
A	GLU309
A	HOH1091

---

site_id	AD1
Number of Residues	4
Details	binding site for residue SO4 A 910

Chain	Residue
A	ALA313
A	ASP314
A	GLU340
A	HIS341

---

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 D 901

Chain	Residue
D	ARG306
D	THR308
D	GLU309

---

site_id	AD3
Number of Residues	18
Details	binding site for Di-nucleotide DG E 8 and DOC E 9

Chain	Residue
D	ARG615
D	GLN624
D	ASN625
D	ILE626
D	PRO627
D	ILE628
D	ARG629
D	VAL828
D	HIS829
D	ASP830
D	HOH1050
E	DA7
E	HOH103
E	HOH106
E	HOH107
F	DG4
F	DC5
F	DT6

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Functional Information from PROSITE/UniProt

site_id	PS00447
Number of Residues	20
Details	DNA_POLYMERASE_A DNA polymerase family A signature. RrqAKavnYGivYgiSdygL

Chain	Residue	Details
A	ARG702-LEU721

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