6UR9
DNA polymerase I Large Fragment from Bacillus stearothermophilus with DNA template, dideoxy primer, 3'-amino-ddGTP (nGTP), and Ca2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006302 | biological_process | double-strand break repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0034061 | molecular_function | DNA polymerase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071897 | biological_process | DNA biosynthetic process |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| D | 0004518 | molecular_function | nuclease activity |
| D | 0004527 | molecular_function | exonuclease activity |
| D | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| D | 0006260 | biological_process | DNA replication |
| D | 0006261 | biological_process | DNA-templated DNA replication |
| D | 0006281 | biological_process | DNA repair |
| D | 0006302 | biological_process | double-strand break repair |
| D | 0006974 | biological_process | DNA damage response |
| D | 0008408 | molecular_function | 3'-5' exonuclease activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016779 | molecular_function | nucleotidyltransferase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0034061 | molecular_function | DNA polymerase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue NG3 A 901 |
| Chain | Residue |
| A | ASP653 |
| A | TYR714 |
| A | ASP830 |
| A | CA902 |
| A | HOH1006 |
| A | HOH1074 |
| B | DOC9 |
| C | DC3 |
| C | DG4 |
| A | TYR654 |
| A | GLN656 |
| A | ILE657 |
| A | GLU658 |
| A | HIS682 |
| A | ARG702 |
| A | LYS706 |
| A | TYR710 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 902 |
| Chain | Residue |
| A | ASP653 |
| A | TYR654 |
| A | ASP830 |
| A | NG3901 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 903 |
| Chain | Residue |
| A | MET299 |
| A | ALA300 |
| A | ARG343 |
| A | ARG677 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 904 |
| Chain | Residue |
| A | GLU321 |
| A | VAL322 |
| A | ASP425 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 905 |
| Chain | Residue |
| A | LYS383 |
| D | GLU501 |
| D | PRO597 |
| D | HOH1020 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 906 |
| Chain | Residue |
| D | LYS498 |
| D | HOH1021 |
| D | HOH1035 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 907 |
| Chain | Residue |
| A | ARG423 |
| A | PRO424 |
| D | ARG779 |
| D | ASN780 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 908 |
| Chain | Residue |
| A | PRO597 |
| A | HOH1012 |
| D | LYS383 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 909 |
| Chain | Residue |
| A | ARG306 |
| A | THR308 |
| A | GLU309 |
| A | HOH1091 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 910 |
| Chain | Residue |
| A | ALA313 |
| A | ASP314 |
| A | GLU340 |
| A | HIS341 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 901 |
| Chain | Residue |
| D | ARG306 |
| D | THR308 |
| D | GLU309 |
| site_id | AD3 |
| Number of Residues | 18 |
| Details | binding site for Di-nucleotide DG E 8 and DOC E 9 |
| Chain | Residue |
| D | ARG615 |
| D | GLN624 |
| D | ASN625 |
| D | ILE626 |
| D | PRO627 |
| D | ILE628 |
| D | ARG629 |
| D | VAL828 |
| D | HIS829 |
| D | ASP830 |
| D | HOH1050 |
| E | DA7 |
| E | HOH103 |
| E | HOH106 |
| E | HOH107 |
| F | DG4 |
| F | DC5 |
| F | DT6 |
Functional Information from PROSITE/UniProt
| site_id | PS00447 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_A DNA polymerase family A signature. RrqAKavnYGivYgiSdygL |
| Chain | Residue | Details |
| A | ARG702-LEU721 |
