6UM4

Crystal structure of malate dehydrogenase from Naegleria fowleri ATCC 30863

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0006108	biological_process	malate metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016615	molecular_function	malate dehydrogenase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
B	0003824	molecular_function	catalytic activity
B	0006108	biological_process	malate metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016615	molecular_function	malate dehydrogenase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
C	0003824	molecular_function	catalytic activity
C	0006108	biological_process	malate metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016615	molecular_function	malate dehydrogenase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
D	0003824	molecular_function	catalytic activity
D	0006108	biological_process	malate metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016615	molecular_function	malate dehydrogenase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
E	0003824	molecular_function	catalytic activity
E	0006108	biological_process	malate metabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0016615	molecular_function	malate dehydrogenase activity
E	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
F	0003824	molecular_function	catalytic activity
F	0006108	biological_process	malate metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0016615	molecular_function	malate dehydrogenase activity
F	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
G	0003824	molecular_function	catalytic activity
G	0006108	biological_process	malate metabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0016615	molecular_function	malate dehydrogenase activity
G	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
G	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
H	0003824	molecular_function	catalytic activity
H	0006108	biological_process	malate metabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0016615	molecular_function	malate dehydrogenase activity
H	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
H	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
I	0003824	molecular_function	catalytic activity
I	0006108	biological_process	malate metabolic process
I	0016491	molecular_function	oxidoreductase activity
I	0016615	molecular_function	malate dehydrogenase activity
I	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
I	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
J	0003824	molecular_function	catalytic activity
J	0006108	biological_process	malate metabolic process
J	0016491	molecular_function	oxidoreductase activity
J	0016615	molecular_function	malate dehydrogenase activity
J	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
J	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
K	0003824	molecular_function	catalytic activity
K	0006108	biological_process	malate metabolic process
K	0016491	molecular_function	oxidoreductase activity
K	0016615	molecular_function	malate dehydrogenase activity
K	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
K	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
L	0003824	molecular_function	catalytic activity
L	0006108	biological_process	malate metabolic process
L	0016491	molecular_function	oxidoreductase activity
L	0016615	molecular_function	malate dehydrogenase activity
L	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
L	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue EDO D 501

Chain	Residue
D	TYR364
D	GLU388
K	ASP304

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site_id	AC2
Number of Residues	3
Details	binding site for residue EDO J 501

Chain	Residue
A	TYR364
J	ASP304
J	GLN306

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site_id	AC3
Number of Residues	2
Details	binding site for residue EDO J 502

Chain	Residue
A	ASP304
J	TYR364

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site_id	AC4
Number of Residues	5
Details	binding site for residue EDO L 501

Chain	Residue
C	GLN306
L	TYR364
L	GLU388
L	HOH618
C	ASP304

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