Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6UKO

Structure analysis of full-length mouse bcs1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0007005	biological_process	mitochondrion organization
A	0008566	molecular_function	mitochondrial protein-transporting ATPase activity
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
A	0032981	biological_process	mitochondrial respiratory chain complex I assembly
A	0033617	biological_process	mitochondrial cytochrome c oxidase assembly
A	0034551	biological_process	mitochondrial respiratory chain complex III assembly
A	0071806	biological_process	protein transmembrane transport
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0007005	biological_process	mitochondrion organization
B	0008566	molecular_function	mitochondrial protein-transporting ATPase activity
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
B	0032981	biological_process	mitochondrial respiratory chain complex I assembly
B	0033617	biological_process	mitochondrial cytochrome c oxidase assembly
B	0034551	biological_process	mitochondrial respiratory chain complex III assembly
B	0071806	biological_process	protein transmembrane transport
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0007005	biological_process	mitochondrion organization
C	0008566	molecular_function	mitochondrial protein-transporting ATPase activity
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
C	0032981	biological_process	mitochondrial respiratory chain complex I assembly
C	0033617	biological_process	mitochondrial cytochrome c oxidase assembly
C	0034551	biological_process	mitochondrial respiratory chain complex III assembly
C	0071806	biological_process	protein transmembrane transport
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0007005	biological_process	mitochondrion organization
D	0008566	molecular_function	mitochondrial protein-transporting ATPase activity
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
D	0032981	biological_process	mitochondrial respiratory chain complex I assembly
D	0033617	biological_process	mitochondrial cytochrome c oxidase assembly
D	0034551	biological_process	mitochondrial respiratory chain complex III assembly
D	0071806	biological_process	protein transmembrane transport
E	0000166	molecular_function	nucleotide binding
E	0005524	molecular_function	ATP binding
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0007005	biological_process	mitochondrion organization
E	0008566	molecular_function	mitochondrial protein-transporting ATPase activity
E	0016020	cellular_component	membrane
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
E	0032981	biological_process	mitochondrial respiratory chain complex I assembly
E	0033617	biological_process	mitochondrial cytochrome c oxidase assembly
E	0034551	biological_process	mitochondrial respiratory chain complex III assembly
E	0071806	biological_process	protein transmembrane transport
F	0000166	molecular_function	nucleotide binding
F	0005524	molecular_function	ATP binding
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0007005	biological_process	mitochondrion organization
F	0008566	molecular_function	mitochondrial protein-transporting ATPase activity
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
F	0032981	biological_process	mitochondrial respiratory chain complex I assembly
F	0033617	biological_process	mitochondrial cytochrome c oxidase assembly
F	0034551	biological_process	mitochondrial respiratory chain complex III assembly
F	0071806	biological_process	protein transmembrane transport
G	0000166	molecular_function	nucleotide binding
G	0005524	molecular_function	ATP binding
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0007005	biological_process	mitochondrion organization
G	0008566	molecular_function	mitochondrial protein-transporting ATPase activity
G	0016020	cellular_component	membrane
G	0016787	molecular_function	hydrolase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
G	0032981	biological_process	mitochondrial respiratory chain complex I assembly
G	0033617	biological_process	mitochondrial cytochrome c oxidase assembly
G	0034551	biological_process	mitochondrial respiratory chain complex III assembly
G	0071806	biological_process	protein transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue ADP A 1800

Chain	Residue
A	ARG1186
A	SER1237
A	SER1238
A	ASN1332
A	PRO1393
A	GLN1397
A	MG1801
B	GLY1219
A	SER1190
A	VAL1191
A	VAL1192
A	LEU1193
A	GLY1233
A	CYS1234
A	GLY1235
A	LYS1236

site_id	AC2
Number of Residues	4
Details	binding site for residue MG A 1801

Chain	Residue
A	GLU1282
A	ASP1283
A	ASN1332
A	ADP1800

site_id	AC3
Number of Residues	14
Details	binding site for residue ADP B 1800

Chain	Residue
B	ARG1186
B	SER1190
B	VAL1191
B	VAL1192
B	LEU1193
B	GLY1233
B	CYS1234
B	GLY1235
B	LYS1236
B	SER1237
B	SER1238
B	GLN1397
B	MG1801
C	GLY1219

site_id	AC4
Number of Residues	3
Details	binding site for residue MG B 1801

Chain	Residue
B	GLU1282
B	ASP1283
B	ADP1800

site_id	AC5
Number of Residues	13
Details	binding site for residue ADP C 1800

Chain	Residue
C	ARG1186
C	SER1190
C	VAL1191
C	VAL1192
C	LEU1193
C	GLY1233
C	CYS1234
C	GLY1235
C	LYS1236
C	SER1237
C	SER1238
C	GLN1397
C	MG1801

site_id	AC6
Number of Residues	4
Details	binding site for residue MG C 1801

Chain	Residue
C	GLU1282
C	ASP1283
C	ASN1332
C	ADP1800

site_id	AC7
Number of Residues	16
Details	binding site for residue ADP D 1800

Chain	Residue
D	ARG1186
D	SER1190
D	VAL1191
D	VAL1192
D	LEU1193
D	GLY1233
D	CYS1234
D	GLY1235
D	LYS1236
D	SER1237
D	SER1238
D	ASN1332
D	PRO1393
D	GLN1397
D	MG1801
E	GLY1219

site_id	AC8
Number of Residues	4
Details	binding site for residue MG D 1801

Chain	Residue
D	GLU1282
D	ASP1283
D	ASN1332
D	ADP1800

site_id	AC9
Number of Residues	15
Details	binding site for residue ADP E 1800

Chain	Residue
E	ARG1186
E	SER1190
E	VAL1191
E	VAL1192
E	LEU1193
E	GLY1233
E	CYS1234
E	GLY1235
E	LYS1236
E	SER1237
E	SER1238
E	PRO1393
E	GLN1397
E	MG1801
F	GLY1219

site_id	AD1
Number of Residues	3
Details	binding site for residue MG E 1801

Chain	Residue
E	SER1237
E	ASP1283
E	ADP1800

site_id	AD2
Number of Residues	15
Details	binding site for residue ADP F 1800

Chain	Residue
F	GLY1235
F	LYS1236
F	SER1237
F	SER1238
F	GLN1360
F	GLN1397
F	MG1801
G	GLY1219
F	ARG1186
F	SER1190
F	VAL1191
F	VAL1192
F	LEU1193
F	GLY1233
F	CYS1234

site_id	AD3
Number of Residues	4
Details	binding site for residue MG F 1801

Chain	Residue
F	SER1237
F	GLU1282
F	ASP1283
F	ADP1800

site_id	AD4
Number of Residues	14
Details	binding site for residue ADP G 1800

Chain	Residue
A	GLY1219
G	ARG1186
G	SER1190
G	VAL1191
G	VAL1192
G	LEU1193
G	GLY1233
G	CYS1234
G	GLY1235
G	LYS1236
G	SER1237
G	SER1238
G	GLN1397
G	MG1801

site_id	AD5
Number of Residues	2
Details	binding site for residue MG G 1801

Chain	Residue
G	ASP1283
G	ADP1800

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. RiVFmTTNyidrLDpALi.R

Chain	Residue	Details
A	ARG1325-ARG1343

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	91
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000255

Chain	Residue	Details
A	PRO1002-TYR1015
B	PRO1002-TYR1015
C	PRO1002-TYR1015
D	PRO1002-TYR1015
E	PRO1002-TYR1015
F	PRO1002-TYR1015
G	PRO1002-TYR1015

site_id	SWS_FT_FI2
Number of Residues	112
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	PHE1016-ALA1032
B	PHE1016-ALA1032
C	PHE1016-ALA1032
D	PHE1016-ALA1032
E	PHE1016-ALA1032
F	PHE1016-ALA1032
G	PHE1016-ALA1032

site_id	SWS_FT_FI3
Number of Residues	2695
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000255

Chain	Residue	Details
A	ARG1033-ARG1418
B	ARG1033-ARG1418
C	ARG1033-ARG1418
D	ARG1033-ARG1418
E	ARG1033-ARG1418
F	ARG1033-ARG1418
G	ARG1033-ARG1418

site_id	SWS_FT_FI4
Number of Residues	7
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY1230
B	GLY1230
C	GLY1230
D	GLY1230
E	GLY1230
F	GLY1230
G	GLY1230

site_id	SWS_FT_FI5
Number of Residues	7
Details	MOD_RES: Phosphotyrosine => ECO:0000250\|UniProtKB:Q9Y276

Chain	Residue	Details
A	TYR1181
B	TYR1181
C	TYR1181
D	TYR1181
E	TYR1181
F	TYR1181
G	TYR1181

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)