Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008150 | biological_process | biological_process |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0050664 | molecular_function | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008150 | biological_process | biological_process |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0050664 | molecular_function | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue NAP A 301 |
| Chain | Residue |
| A | GLY9 |
| A | ASN85 |
| A | ALA86 |
| A | GLY87 |
| A | ILE109 |
| A | SER136 |
| A | SER137 |
| A | TYR150 |
| A | LYS154 |
| A | PRO178 |
| A | GLY179 |
| A | SER11 |
| A | VAL181 |
| A | THR183 |
| A | MET185 |
| A | GLN186 |
| A | ARG12 |
| A | ILE14 |
| A | ARG36 |
| A | SER37 |
| A | GLY57 |
| A | ASP58 |
| A | ILE59 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | binding site for residue NAP B 301 |
| Chain | Residue |
| B | GLY9 |
| B | SER11 |
| B | ARG12 |
| B | GLY13 |
| B | ILE14 |
| B | ALA35 |
| B | ARG36 |
| B | SER37 |
| B | ASP58 |
| B | ILE59 |
| B | ASN85 |
| B | ALA86 |
| B | GLY87 |
| B | VAL135 |
| B | SER136 |
| B | SER137 |
| B | TYR150 |
| B | LYS154 |
| B | PRO178 |
| B | GLY179 |
| B | VAL181 |
| B | THR183 |
| B | ASP184 |
| B | MET185 |
| B | GLN186 |
| B | HOH421 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SdacnmyfssWgaYGSSKAALnHFAmTLA |
| Chain | Residue | Details |
| A | SER137-ALA165 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O93868","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10001","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Lowers pKa of active site Tyr","evidences":[{"source":"UniProtKB","id":"O93868","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"L0E2Z4","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O93868","evidenceCode":"ECO:0000250"}]} |
6UHX
