6UEG

Pseudomonas aeruginosa LpxA Complex Structure with Ligand

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008610	biological_process	lipid biosynthetic process
A	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
A	0009245	biological_process	lipid A biosynthetic process
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0008610	biological_process	lipid biosynthetic process
B	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
B	0009245	biological_process	lipid A biosynthetic process
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0008610	biological_process	lipid biosynthetic process
C	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
C	0009245	biological_process	lipid A biosynthetic process
C	0016020	cellular_component	membrane
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
D	0005737	cellular_component	cytoplasm
D	0008610	biological_process	lipid biosynthetic process
D	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
D	0009245	biological_process	lipid A biosynthetic process
D	0016020	cellular_component	membrane
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
E	0005737	cellular_component	cytoplasm
E	0008610	biological_process	lipid biosynthetic process
E	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
E	0009245	biological_process	lipid A biosynthetic process
E	0016020	cellular_component	membrane
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
F	0005737	cellular_component	cytoplasm
F	0008610	biological_process	lipid biosynthetic process
F	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
F	0009245	biological_process	lipid A biosynthetic process
F	0016020	cellular_component	membrane
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue Q5G A 301

Chain	Residue
A	THR68
C	ASN133
C	SER150
C	GLY151
C	MET169
C	HOH500
A	HIS118
A	ALA138
A	HIS156
A	GLN157
A	HOH401
A	HOH411
A	HOH436
C	VAL132

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site_id	AC2
Number of Residues	10
Details	binding site for residue Q5G A 302

Chain	Residue
A	VAL132
A	ASN133
A	ILE148
A	SER150
A	GLY151
A	HOH432
B	ASP70
B	HIS118
B	ALA136
B	ALA138

---

site_id	AC3
Number of Residues	2
Details	binding site for residue CA B 301

Chain	Residue
B	ARG258
B	HOH475

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site_id	AC4
Number of Residues	12
Details	binding site for residue Q5G C 301

Chain	Residue
B	VAL132
B	ASN133
B	SER150
B	GLY151
B	MET169
C	ASP70
C	HIS118
C	HIS121
C	ALA138
C	HIS156
C	GLN157
C	HOH438

---

site_id	AC5
Number of Residues	12
Details	binding site for residue Q5G D 301

Chain	Residue
D	THR68
D	HIS118
D	ALA138
D	HIS156
D	GLN157
D	HOH414
D	HOH421
D	HOH427
E	VAL132
E	ASN133
E	SER150
E	GLY151

---

site_id	AC6
Number of Residues	15
Details	binding site for residue Q5G E 301

Chain	Residue
E	ASP70
E	HIS118
E	HIS121
E	ALA138
E	HIS156
E	GLN157
E	HOH409
E	HOH415
E	HOH416
E	HOH428
F	VAL132
F	ASN133
F	SER150
F	GLY151
F	MET169

---

site_id	AC7
Number of Residues	14
Details	binding site for residue Q5G F 301

Chain	Residue
D	VAL132
D	ASN133
D	SER150
D	GLY151
D	MET169
F	ASP70
F	HIS118
F	HIS121
F	ALA138
F	HIS156
F	GLN157
F	ARG254
F	HOH438
F	HOH512

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Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IDprAiIdpsArLAadVqVGpwSiVgaeV

Chain	Residue	Details
A	ILE4-VAL32

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