6UE9
Structure of tetrameric sIgA complex (Class 2)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| D | 0002250 | biological_process | adaptive immune response |
| D | 0003094 | biological_process | glomerular filtration |
| D | 0003697 | molecular_function | single-stranded DNA binding |
| D | 0003823 | molecular_function | antigen binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005615 | cellular_component | extracellular space |
| D | 0006955 | biological_process | immune response |
| D | 0006959 | biological_process | humoral immune response |
| D | 0019731 | biological_process | antibacterial humoral response |
| D | 0019862 | molecular_function | IgA binding |
| D | 0030674 | molecular_function | protein-macromolecule adaptor activity |
| D | 0031210 | molecular_function | phosphatidylcholine binding |
| D | 0034987 | molecular_function | immunoglobulin receptor binding |
| D | 0042803 | molecular_function | protein homodimerization activity |
| D | 0042834 | molecular_function | peptidoglycan binding |
| D | 0045087 | biological_process | innate immune response |
| D | 0060267 | biological_process | positive regulation of respiratory burst |
| D | 0065003 | biological_process | protein-containing complex assembly |
| D | 0070062 | cellular_component | extracellular exosome |
| D | 0071748 | cellular_component | monomeric IgA immunoglobulin complex |
| D | 0071750 | cellular_component | dimeric IgA immunoglobulin complex |
| D | 0071751 | cellular_component | secretory IgA immunoglobulin complex |
| D | 0071752 | cellular_component | secretory dimeric IgA immunoglobulin complex |
| D | 0071756 | cellular_component | pentameric IgM immunoglobulin complex |
| D | 0071757 | cellular_component | hexameric IgM immunoglobulin complex |
| D | 0072562 | cellular_component | blood microparticle |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FTCTAAH |
| Chain | Residue | Details |
| A | PHE321-HIS327 | |
| A | PHE430-HIS436 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:25946035, ECO:0000269|PubMed:407930 |
| Chain | Residue | Details |
| D | GLN1 | |
| B | ASN263 | |
| F | ASN263 | |
| G | ASN263 | |
| E | ASN263 | |
| H | ASN263 | |
| K | ASN263 | |
| L | ASN263 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| D | ASN49 | |
| B | ASN337 | |
| F | ASN337 | |
| G | ASN337 | |
| E | ASN337 | |
| H | ASN337 | |
| K | ASN337 | |
| L | ASN337 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:6526384 |
| Chain | Residue | Details |
| C | ASN117 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:6526384 |
| Chain | Residue | Details |
| C | ASN168 | |
| C | ASN481 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6526384 |
| Chain | Residue | Details |
| C | ASN403 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:6526384 |
| Chain | Residue | Details |
| C | ASN451 |
