Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004769 | molecular_function | steroid Delta-isomerase activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008202 | biological_process | steroid metabolic process |
| A | 0016853 | molecular_function | isomerase activity |
| B | 0004769 | molecular_function | steroid Delta-isomerase activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008202 | biological_process | steroid metabolic process |
| B | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ASD B 201 |
| Chain | Residue |
| A | TRP92 |
| B | MET90 |
| B | LEU99 |
| B | ASP103 |
| B | TRP120 |
| B | HOH337 |
| B | HOH339 |
| B | HOH342 |
| A | ASN93 |
| B | TYR16 |
| B | VAL20 |
| B | ASP40 |
| B | PHE56 |
| B | GLY60 |
| B | LEU61 |
| B | PHE86 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CL B 202 |
| Chain | Residue |
| A | THR71 |
| A | HOH335 |
| A | HOH401 |
| B | GLY72 |
| B | ARG75 |
| B | HOH373 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue ASD A 201 |
| Chain | Residue |
| A | TYR16 |
| A | ASP40 |
| A | PHE56 |
| A | MET90 |
| A | LEU99 |
| A | ASP103 |
| A | MET116 |
| A | TRP120 |
| A | HOH326 |
| A | HOH372 |
| A | HOH374 |
| B | TRP92 |
| B | ASN93 |
| B | HOH349 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 202 |
| Chain | Residue |
| A | GLU18 |
| A | ASP21 |
| A | HOH383 |
| A | HOH384 |
| A | HOH407 |
| A | HOH415 |
| A | HOH448 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 203 |
| Chain | Residue |
| A | HOH303 |
| A | HOH348 |
| A | HOH355 |
| A | HOH379 |
| A | HOH426 |
| A | HOH429 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 204 |
| Chain | Residue |
| A | GLY72 |
| A | ARG75 |
| A | HOH389 |
| A | HOH401 |
| B | THR71 |
| B | HOH386 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11007792","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 349 |
| Chain | Residue | Details |
| A | TYR16 | proton acceptor, proton donor |
| A | ASP40 | proton acceptor, proton donor |
| A | ASP100 | electrostatic stabiliser |
| A | ASP103 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 349 |
| Chain | Residue | Details |
| B | TYR16 | proton acceptor, proton donor |
| B | ASP40 | proton acceptor, proton donor |
| B | ASP100 | electrostatic stabiliser |
| B | ASP103 | electrostatic stabiliser |
