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6UAO

Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with the peptide EEYSAM

Functional Information from GO Data
ChainGOidnamespacecontents
S0004252molecular_functionserine-type endopeptidase activity
S0006508biological_processproteolysis
S0008236molecular_functionserine-type peptidase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue NA S 301
ChainResidue
SALA169
STYR171
SVAL174
SHOH404
SHOH540

site_idAC2
Number of Residues6
Detailsbinding site for residue CL S 302
ChainResidue
STYR167
STYR171
BTYR277
SGLY131
SSER132
SVAL135

site_idAC3
Number of Residues8
Detailsbinding site for residue EDO S 303
ChainResidue
SASN118
SMET119
SSER145
SGLY146
SHOH418
SHOH442
SHOH498
SHOH508

site_idAC4
Number of Residues9
Detailsbinding site for residue EDO S 304
ChainResidue
SGLN10
SSER130
SSER132
SALA133
STYR171
SASN184
SLEU267
SHOH405
SHOH481

site_idAC5
Number of Residues5
Detailsbinding site for residue EDO S 305
ChainResidue
SPRO194
SSER260
SPHE261
SHOH431
SHOH464

site_idAC6
Number of Residues7
Detailsbinding site for residue EDO S 306
ChainResidue
SSER161
SSER162
SSER163
SHOH424
SHOH445
SHOH455
SHOH542

site_idAC7
Number of Residues5
Detailsbinding site for residue EDO S 307
ChainResidue
SASN109
SPHE189
SSER218
SHOH468
SHOH596

Functional Information from PROSITE/UniProt
site_idPS00136
Number of Residues12
DetailsSUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VAILDTGIdssH
ChainResidueDetails
SVAL28-HIS39

site_idPS00138
Number of Residues11
DetailsSUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSmAsPhVAG
ChainResidueDetails
SGLY219-GLY229

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PDB entries from 2024-11-06

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