6UAE

Ketosteroid isomerase (C. testosteroni) with truncated & designed loop for precise positioning of a catalytic E38

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004769	molecular_function	steroid delta-isomerase activity
A	0008202	biological_process	steroid metabolic process
A	0016853	molecular_function	isomerase activity
B	0004769	molecular_function	steroid delta-isomerase activity
B	0008202	biological_process	steroid metabolic process
B	0016853	molecular_function	isomerase activity
C	0004769	molecular_function	steroid delta-isomerase activity
C	0008202	biological_process	steroid metabolic process
C	0016853	molecular_function	isomerase activity
D	0004769	molecular_function	steroid delta-isomerase activity
D	0008202	biological_process	steroid metabolic process
D	0016853	molecular_function	isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue SO4 A 201

Chain	Residue
A	ARG43
A	GLU53
A	HOH328

---

site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 A 202

Chain	Residue
A	ARG13
A	ARG91
A	HOH306

---

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 203

Chain	Residue
A	ASN104
A	GLY105
A	HOH307

---

site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 204

Chain	Residue
A	ARG102
A	SER111
A	ARG113

---

site_id	AC5
Number of Residues	8
Details	binding site for residue DXC A 205

Chain	Residue
A	TYR14
A	SER58
A	PHE86
A	TYR88
A	ASP99
A	MET112
A	ALA114
A	EQU206

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EQU A 206

Chain	Residue
A	TYR14
A	PHE82
A	VAL84
A	PHE86
A	ASP99
A	MET112
A	DXC205

---

site_id	AC7
Number of Residues	2
Details	binding site for residue SO4 B 201

Chain	Residue
B	HIS6
B	ARG13

---

site_id	AC8
Number of Residues	4
Details	binding site for residue SO4 B 202

Chain	Residue
B	HIS100
B	ARG102
B	SER111
B	ARG113

---

site_id	AC9
Number of Residues	7
Details	binding site for residue EQU B 203

Chain	Residue
B	TYR14
B	PHE82
B	VAL84
B	PHE86
B	ASP99
B	MET112
B	PHE116

---

site_id	AD1
Number of Residues	2
Details	binding site for residue SO4 C 201

Chain	Residue
C	HIS6
C	ARG13

---

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 C 202

Chain	Residue
C	HIS122
C	ALA123
D	HOH339

---

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 C 203

Chain	Residue
C	ASN104
C	GLY105
C	HOH317

---

site_id	AD4
Number of Residues	6
Details	binding site for residue SO4 C 204

Chain	Residue
C	ARG102
C	SER111
C	ARG113
C	HOH302
C	HOH315
C	HOH323

---

site_id	AD5
Number of Residues	6
Details	binding site for residue SO4 C 205

Chain	Residue
C	ARG91
C	LYS92
C	GLY124
C	HOH304
C	HOH362
C	HOH367

---

site_id	AD6
Number of Residues	10
Details	binding site for residue DXC C 206

Chain	Residue
C	TYR14
C	GLU38
C	ASN57
C	SER58
C	VAL84
C	PHE86
C	ASP99
C	MET112
C	ALA114
C	EQU207

---

site_id	AD7
Number of Residues	10
Details	binding site for residue EQU C 207

Chain	Residue
C	TYR14
C	GLU38
C	SER58
C	PHE82
C	VAL84
C	PHE86
C	ASP99
C	MET112
C	ALA114
C	DXC206

---

site_id	AD8
Number of Residues	3
Details	binding site for residue SO4 D 201

Chain	Residue
D	HIS6
D	ARG13
D	HOH304

---

site_id	AD9
Number of Residues	10
Details	binding site for residue DXC D 202

Chain	Residue
D	TYR14
D	GLU38
D	PHE54
D	SER58
D	VAL84
D	PHE86
D	ASP99
D	MET112
D	ALA114
D	PHE116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor

Chain	Residue	Details
A	TYR14
B	TYR14
C	TYR14
D	TYR14

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000269|PubMed:3480517

Chain	Residue	Details
A	GLU38
B	GLU38
C	GLU38
D	GLU38

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
A	ASP99
B	ASP99
C	ASP99
D	ASP99

---