6U9D
Saccharomyces cerevisiae acetohydroxyacid synthase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003984 | molecular_function | acetolactate synthase activity |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005948 | cellular_component | acetolactate synthase complex |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009099 | biological_process | valine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003984 | molecular_function | acetolactate synthase activity |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005948 | cellular_component | acetolactate synthase complex |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0009099 | biological_process | valine biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| C | 1990610 | molecular_function | acetolactate synthase regulator activity |
| D | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| D | 1990610 | molecular_function | acetolactate synthase regulator activity |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0003984 | molecular_function | acetolactate synthase activity |
| E | 0005739 | cellular_component | mitochondrion |
| E | 0005948 | cellular_component | acetolactate synthase complex |
| E | 0008652 | biological_process | amino acid biosynthetic process |
| E | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| E | 0009097 | biological_process | isoleucine biosynthetic process |
| E | 0009099 | biological_process | valine biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0030976 | molecular_function | thiamine pyrophosphate binding |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0003984 | molecular_function | acetolactate synthase activity |
| F | 0005739 | cellular_component | mitochondrion |
| F | 0005948 | cellular_component | acetolactate synthase complex |
| F | 0008652 | biological_process | amino acid biosynthetic process |
| F | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| F | 0009097 | biological_process | isoleucine biosynthetic process |
| F | 0009099 | biological_process | valine biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0030976 | molecular_function | thiamine pyrophosphate binding |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| G | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| G | 1990610 | molecular_function | acetolactate synthase regulator activity |
| H | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| H | 1990610 | molecular_function | acetolactate synthase regulator activity |
| I | 0000287 | molecular_function | magnesium ion binding |
| I | 0003824 | molecular_function | catalytic activity |
| I | 0003984 | molecular_function | acetolactate synthase activity |
| I | 0005739 | cellular_component | mitochondrion |
| I | 0005948 | cellular_component | acetolactate synthase complex |
| I | 0008652 | biological_process | amino acid biosynthetic process |
| I | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| I | 0009097 | biological_process | isoleucine biosynthetic process |
| I | 0009099 | biological_process | valine biosynthetic process |
| I | 0016740 | molecular_function | transferase activity |
| I | 0030976 | molecular_function | thiamine pyrophosphate binding |
| I | 0046872 | molecular_function | metal ion binding |
| I | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| J | 0000287 | molecular_function | magnesium ion binding |
| J | 0003824 | molecular_function | catalytic activity |
| J | 0003984 | molecular_function | acetolactate synthase activity |
| J | 0005739 | cellular_component | mitochondrion |
| J | 0005948 | cellular_component | acetolactate synthase complex |
| J | 0008652 | biological_process | amino acid biosynthetic process |
| J | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| J | 0009097 | biological_process | isoleucine biosynthetic process |
| J | 0009099 | biological_process | valine biosynthetic process |
| J | 0016740 | molecular_function | transferase activity |
| J | 0030976 | molecular_function | thiamine pyrophosphate binding |
| J | 0046872 | molecular_function | metal ion binding |
| J | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| K | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| K | 1990610 | molecular_function | acetolactate synthase regulator activity |
| L | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| L | 1990610 | molecular_function | acetolactate synthase regulator activity |
| M | 0000287 | molecular_function | magnesium ion binding |
| M | 0003824 | molecular_function | catalytic activity |
| M | 0003984 | molecular_function | acetolactate synthase activity |
| M | 0005739 | cellular_component | mitochondrion |
| M | 0005948 | cellular_component | acetolactate synthase complex |
| M | 0008652 | biological_process | amino acid biosynthetic process |
| M | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| M | 0009097 | biological_process | isoleucine biosynthetic process |
| M | 0009099 | biological_process | valine biosynthetic process |
| M | 0016740 | molecular_function | transferase activity |
| M | 0030976 | molecular_function | thiamine pyrophosphate binding |
| M | 0046872 | molecular_function | metal ion binding |
| M | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| N | 0000287 | molecular_function | magnesium ion binding |
| N | 0003824 | molecular_function | catalytic activity |
| N | 0003984 | molecular_function | acetolactate synthase activity |
| N | 0005739 | cellular_component | mitochondrion |
| N | 0005948 | cellular_component | acetolactate synthase complex |
| N | 0008652 | biological_process | amino acid biosynthetic process |
| N | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| N | 0009097 | biological_process | isoleucine biosynthetic process |
| N | 0009099 | biological_process | valine biosynthetic process |
| N | 0016740 | molecular_function | transferase activity |
| N | 0030976 | molecular_function | thiamine pyrophosphate binding |
| N | 0046872 | molecular_function | metal ion binding |
| N | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| O | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| O | 1990610 | molecular_function | acetolactate synthase regulator activity |
| P | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| P | 1990610 | molecular_function | acetolactate synthase regulator activity |
| Q | 0000287 | molecular_function | magnesium ion binding |
| Q | 0003824 | molecular_function | catalytic activity |
| Q | 0003984 | molecular_function | acetolactate synthase activity |
| Q | 0005739 | cellular_component | mitochondrion |
| Q | 0005948 | cellular_component | acetolactate synthase complex |
| Q | 0008652 | biological_process | amino acid biosynthetic process |
| Q | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| Q | 0009097 | biological_process | isoleucine biosynthetic process |
| Q | 0009099 | biological_process | valine biosynthetic process |
| Q | 0016740 | molecular_function | transferase activity |
| Q | 0030976 | molecular_function | thiamine pyrophosphate binding |
| Q | 0046872 | molecular_function | metal ion binding |
| Q | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| R | 0000287 | molecular_function | magnesium ion binding |
| R | 0003824 | molecular_function | catalytic activity |
| R | 0003984 | molecular_function | acetolactate synthase activity |
| R | 0005739 | cellular_component | mitochondrion |
| R | 0005948 | cellular_component | acetolactate synthase complex |
| R | 0008652 | biological_process | amino acid biosynthetic process |
| R | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| R | 0009097 | biological_process | isoleucine biosynthetic process |
| R | 0009099 | biological_process | valine biosynthetic process |
| R | 0016740 | molecular_function | transferase activity |
| R | 0030976 | molecular_function | thiamine pyrophosphate binding |
| R | 0046872 | molecular_function | metal ion binding |
| R | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| S | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| S | 1990610 | molecular_function | acetolactate synthase regulator activity |
| T | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| T | 1990610 | molecular_function | acetolactate synthase regulator activity |
| U | 0000287 | molecular_function | magnesium ion binding |
| U | 0003824 | molecular_function | catalytic activity |
| U | 0003984 | molecular_function | acetolactate synthase activity |
| U | 0005739 | cellular_component | mitochondrion |
| U | 0005948 | cellular_component | acetolactate synthase complex |
| U | 0008652 | biological_process | amino acid biosynthetic process |
| U | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| U | 0009097 | biological_process | isoleucine biosynthetic process |
| U | 0009099 | biological_process | valine biosynthetic process |
| U | 0016740 | molecular_function | transferase activity |
| U | 0030976 | molecular_function | thiamine pyrophosphate binding |
| U | 0046872 | molecular_function | metal ion binding |
| U | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| V | 0000287 | molecular_function | magnesium ion binding |
| V | 0003824 | molecular_function | catalytic activity |
| V | 0003984 | molecular_function | acetolactate synthase activity |
| V | 0005739 | cellular_component | mitochondrion |
| V | 0005948 | cellular_component | acetolactate synthase complex |
| V | 0008652 | biological_process | amino acid biosynthetic process |
| V | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| V | 0009097 | biological_process | isoleucine biosynthetic process |
| V | 0009099 | biological_process | valine biosynthetic process |
| V | 0016740 | molecular_function | transferase activity |
| V | 0030976 | molecular_function | thiamine pyrophosphate binding |
| V | 0046872 | molecular_function | metal ion binding |
| V | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| W | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| W | 1990610 | molecular_function | acetolactate synthase regulator activity |
| X | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| X | 1990610 | molecular_function | acetolactate synthase regulator activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue TPP A 701 |
| Chain | Residue |
| A | VAL497 |
| A | ASN577 |
| A | GLU579 |
| A | GLN580 |
| A | GLY581 |
| A | MET582 |
| A | VAL583 |
| A | MG702 |
| B | TYR113 |
| B | PRO114 |
| B | GLU139 |
| A | GLY498 |
| B | THR162 |
| B | PRO165 |
| B | GLN202 |
| A | GLN499 |
| A | HIS500 |
| A | GLY523 |
| A | MET525 |
| A | ASP550 |
| A | ALA551 |
| A | SER552 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 702 |
| Chain | Residue |
| A | ASP550 |
| A | ASN577 |
| A | GLU579 |
| A | TPP701 |
| site_id | AC3 |
| Number of Residues | 32 |
| Details | binding site for residue FAD A 703 |
| Chain | Residue |
| A | ASP180 |
| A | ARG241 |
| A | GLY307 |
| A | ALA308 |
| A | GLY309 |
| A | ASN312 |
| A | THR334 |
| A | LEU335 |
| A | GLN336 |
| A | LEU352 |
| A | MET354 |
| A | HIS355 |
| A | GLY374 |
| A | ALA375 |
| A | ARG376 |
| A | ASP378 |
| A | ARG380 |
| A | VAL381 |
| A | GLU407 |
| A | VAL408 |
| A | SER409 |
| A | ASN412 |
| A | GLY425 |
| A | ASP426 |
| A | ALA427 |
| A | GLN501 |
| A | MET502 |
| A | SER519 |
| A | GLY520 |
| A | GLY521 |
| A | 60G704 |
| B | PHE201 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue 60G A 704 |
| Chain | Residue |
| A | MET354 |
| A | ASP379 |
| A | ARG380 |
| A | MET582 |
| A | VAL583 |
| A | TRP586 |
| A | FAD703 |
| A | HOH803 |
| B | GLY116 |
| B | ALA117 |
| B | VAL191 |
| B | PRO192 |
| B | PHE201 |
| B | GLN202 |
| B | LYS251 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | binding site for residue TPP B 701 |
| Chain | Residue |
| A | TYR113 |
| A | PRO114 |
| A | GLU139 |
| A | THR162 |
| A | PRO165 |
| A | GLN202 |
| B | VAL497 |
| B | GLY498 |
| B | GLN499 |
| B | HIS500 |
| B | GLY523 |
| B | MET525 |
| B | ASP550 |
| B | ALA551 |
| B | SER552 |
| B | ASN577 |
| B | GLU579 |
| B | GLN580 |
| B | GLY581 |
| B | MET582 |
| B | VAL583 |
| B | MG702 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 702 |
| Chain | Residue |
| B | ASP550 |
| B | ASN577 |
| B | GLU579 |
| B | TPP701 |
| site_id | AC7 |
| Number of Residues | 31 |
| Details | binding site for residue FAD B 703 |
| Chain | Residue |
| A | PHE201 |
| B | ASP180 |
| B | ARG241 |
| B | GLY307 |
| B | ALA308 |
| B | GLY309 |
| B | ASN312 |
| B | THR334 |
| B | LEU335 |
| B | GLN336 |
| B | LEU352 |
| B | GLY353 |
| B | MET354 |
| B | HIS355 |
| B | GLY374 |
| B | ALA375 |
| B | ARG376 |
| B | ASP378 |
| B | ARG380 |
| B | VAL381 |
| B | GLU407 |
| B | VAL408 |
| B | ASN412 |
| B | GLY425 |
| B | ASP426 |
| B | ALA427 |
| B | GLN501 |
| B | MET502 |
| B | SER519 |
| B | GLY520 |
| B | GLY521 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for residue 60G B 704 |
| Chain | Residue |
| A | GLY116 |
| A | ALA117 |
| A | VAL191 |
| A | PRO192 |
| A | ALA200 |
| A | PHE201 |
| A | LYS251 |
| B | MET354 |
| B | ASP379 |
| B | ARG380 |
| B | MET582 |
| B | TRP586 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | binding site for residue ATP C 401 |
| Chain | Residue |
| C | ASN231 |
| C | PHE232 |
| C | LYS251 |
| C | ARG254 |
| C | ALA257 |
| C | MG402 |
| O | VAL237 |
| O | ASP238 |
| O | ILE239 |
| P | ARG159 |
| P | LYS251 |
| P | ARG254 |
| P | ARG280 |
| P | ATP401 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue MG C 402 |
| Chain | Residue |
| C | ARG254 |
| C | ATP401 |
| P | ARG254 |
| P | ATP401 |
| site_id | AD2 |
| Number of Residues | 13 |
| Details | binding site for residue ATP D 401 |
| Chain | Residue |
| D | ASN231 |
| D | PHE232 |
| D | LYS251 |
| D | ARG254 |
| D | ALA257 |
| D | MG402 |
| G | ARG159 |
| G | LYS251 |
| G | ARG254 |
| G | ATP401 |
| H | VAL237 |
| H | ASP238 |
| H | ILE239 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 402 |
| Chain | Residue |
| D | ARG254 |
| D | ATP401 |
| G | ARG254 |
| G | ATP401 |
| site_id | AD4 |
| Number of Residues | 22 |
| Details | binding site for residue TPP E 701 |
| Chain | Residue |
| E | VAL497 |
| E | GLN499 |
| E | HIS500 |
| E | GLY523 |
| E | MET525 |
| E | GLY549 |
| E | ASP550 |
| E | ALA551 |
| E | SER552 |
| E | ASN577 |
| E | GLU579 |
| E | GLN580 |
| E | GLY581 |
| E | VAL583 |
| E | MG702 |
| F | TYR113 |
| F | PRO114 |
| F | GLU139 |
| F | THR162 |
| F | PRO165 |
| F | ASN169 |
| F | GLN202 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue MG E 702 |
| Chain | Residue |
| E | ASP550 |
| E | ASN577 |
| E | GLU579 |
| E | TPP701 |
| site_id | AD6 |
| Number of Residues | 32 |
| Details | binding site for residue FAD E 703 |
| Chain | Residue |
| E | ASP180 |
| E | ARG241 |
| E | GLY307 |
| E | ALA308 |
| E | GLY309 |
| E | ASN312 |
| E | THR334 |
| E | LEU335 |
| E | GLN336 |
| E | LEU352 |
| E | MET354 |
| E | HIS355 |
| E | GLY374 |
| E | ALA375 |
| E | ARG376 |
| E | ASP378 |
| E | ARG380 |
| E | VAL381 |
| E | GLU407 |
| E | VAL408 |
| E | SER409 |
| E | ASN412 |
| E | GLY425 |
| E | ASP426 |
| E | ALA427 |
| E | GLN501 |
| E | MET502 |
| E | SER519 |
| E | GLY520 |
| E | GLY521 |
| E | 60G704 |
| F | PHE201 |
| site_id | AD7 |
| Number of Residues | 13 |
| Details | binding site for residue 60G E 704 |
| Chain | Residue |
| E | MET354 |
| E | ASP379 |
| E | ARG380 |
| E | MET582 |
| E | TRP586 |
| E | FAD703 |
| F | GLY116 |
| F | ALA117 |
| F | VAL191 |
| F | PRO192 |
| F | ALA200 |
| F | PHE201 |
| F | LYS251 |
| site_id | AD8 |
| Number of Residues | 22 |
| Details | binding site for residue TPP F 701 |
| Chain | Residue |
| E | TYR113 |
| E | PRO114 |
| E | GLU139 |
| E | PRO165 |
| E | ASN169 |
| E | GLN202 |
| F | VAL497 |
| F | GLY498 |
| F | GLN499 |
| F | HIS500 |
| F | GLY523 |
| F | MET525 |
| F | ASP550 |
| F | ALA551 |
| F | SER552 |
| F | ASN577 |
| F | GLU579 |
| F | GLN580 |
| F | GLY581 |
| F | MET582 |
| F | VAL583 |
| F | MG702 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue MG F 702 |
| Chain | Residue |
| F | ASP550 |
| F | LEU575 |
| F | ASN577 |
| F | GLU579 |
| F | TPP701 |
| site_id | AE1 |
| Number of Residues | 32 |
| Details | binding site for residue FAD F 703 |
| Chain | Residue |
| E | PHE201 |
| F | ASP180 |
| F | ARG241 |
| F | GLY307 |
| F | ALA308 |
| F | GLY309 |
| F | ASN312 |
| F | THR334 |
| F | LEU335 |
| F | GLN336 |
| F | LEU352 |
| F | GLY353 |
| F | MET354 |
| F | HIS355 |
| F | GLY374 |
| F | ALA375 |
| F | ARG376 |
| F | ASP378 |
| F | ARG380 |
| F | VAL381 |
| F | PHE406 |
| F | GLU407 |
| F | VAL408 |
| F | ASN412 |
| F | GLY425 |
| F | ASP426 |
| F | ALA427 |
| F | GLN501 |
| F | MET502 |
| F | SER519 |
| F | GLY520 |
| F | GLY521 |
| site_id | AE2 |
| Number of Residues | 12 |
| Details | binding site for residue 60G F 704 |
| Chain | Residue |
| E | GLY116 |
| E | ALA117 |
| E | VAL191 |
| E | PRO192 |
| E | PHE201 |
| E | LYS251 |
| F | MET354 |
| F | ASP379 |
| F | ARG380 |
| F | MET582 |
| F | VAL583 |
| F | TRP586 |
| site_id | AE3 |
| Number of Residues | 14 |
| Details | binding site for residue ATP G 401 |
| Chain | Residue |
| C | VAL237 |
| C | ASP238 |
| C | ILE239 |
| D | ARG159 |
| D | LYS251 |
| D | ARG254 |
| D | ARG280 |
| D | ATP401 |
| D | MG402 |
| G | ASN231 |
| G | PHE232 |
| G | LYS251 |
| G | ARG254 |
| G | ALA257 |
| site_id | AE4 |
| Number of Residues | 15 |
| Details | binding site for residue ATP H 401 |
| Chain | Residue |
| H | ASN231 |
| H | PHE232 |
| H | LYS251 |
| H | ARG254 |
| H | ALA257 |
| H | MG402 |
| K | GLU155 |
| K | ARG159 |
| K | LYS251 |
| K | ARG254 |
| K | ARG280 |
| K | ATP401 |
| L | VAL237 |
| L | ASP238 |
| L | ILE239 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue MG H 402 |
| Chain | Residue |
| H | ATP401 |
| K | ATP401 |
| site_id | AE6 |
| Number of Residues | 20 |
| Details | binding site for residue TPP I 701 |
| Chain | Residue |
| I | VAL497 |
| I | GLY498 |
| I | GLN499 |
| I | HIS500 |
| I | GLY523 |
| I | MET525 |
| I | ASP550 |
| I | ALA551 |
| I | SER552 |
| I | ASN577 |
| I | GLU579 |
| I | GLN580 |
| I | GLY581 |
| I | MET582 |
| I | VAL583 |
| I | MG702 |
| J | PRO114 |
| J | GLU139 |
| J | PRO165 |
| J | GLN202 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue MG I 702 |
| Chain | Residue |
| I | ASP550 |
| I | ASN577 |
| I | GLU579 |
| I | TPP701 |
| site_id | AE8 |
| Number of Residues | 31 |
| Details | binding site for residue FAD I 703 |
| Chain | Residue |
| I | ASP180 |
| I | ARG241 |
| I | GLY307 |
| I | ALA308 |
| I | GLY309 |
| I | ASN312 |
| I | THR334 |
| I | LEU335 |
| I | GLN336 |
| I | LEU352 |
| I | GLY353 |
| I | MET354 |
| I | HIS355 |
| I | GLY374 |
| I | ALA375 |
| I | ARG376 |
| I | ASP378 |
| I | ARG380 |
| I | VAL381 |
| I | GLU407 |
| I | VAL408 |
| I | ASN412 |
| I | ASP426 |
| I | ALA427 |
| I | GLN501 |
| I | MET502 |
| I | SER519 |
| I | GLY520 |
| I | GLY521 |
| I | 60G704 |
| J | PHE201 |
| site_id | AE9 |
| Number of Residues | 13 |
| Details | binding site for residue 60G I 704 |
| Chain | Residue |
| I | MET354 |
| I | ASP379 |
| I | ARG380 |
| I | MET582 |
| I | VAL583 |
| I | TRP586 |
| I | FAD703 |
| J | GLY116 |
| J | ALA117 |
| J | VAL191 |
| J | ALA200 |
| J | PHE201 |
| J | LYS251 |
| site_id | AF1 |
| Number of Residues | 22 |
| Details | binding site for residue TPP J 701 |
| Chain | Residue |
| I | TYR113 |
| I | PRO114 |
| I | GLY115 |
| I | GLU139 |
| I | PRO165 |
| I | ASN169 |
| I | GLN202 |
| J | VAL497 |
| J | GLN499 |
| J | HIS500 |
| J | GLY523 |
| J | MET525 |
| J | ASP550 |
| J | ALA551 |
| J | SER552 |
| J | ASN577 |
| J | GLU579 |
| J | GLN580 |
| J | GLY581 |
| J | MET582 |
| J | VAL583 |
| J | MG702 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue MG J 702 |
| Chain | Residue |
| J | ASP550 |
| J | ASN577 |
| J | GLU579 |
| J | TPP701 |
| site_id | AF3 |
| Number of Residues | 31 |
| Details | binding site for residue FAD J 703 |
| Chain | Residue |
| I | PHE201 |
| J | ASP180 |
| J | ARG241 |
| J | GLY307 |
| J | ALA308 |
| J | GLY309 |
| J | ASN312 |
| J | THR334 |
| J | LEU335 |
| J | LEU352 |
| J | GLY353 |
| J | MET354 |
| J | HIS355 |
| J | GLY374 |
| J | ALA375 |
| J | ARG376 |
| J | ASP378 |
| J | ARG380 |
| J | VAL381 |
| J | GLU407 |
| J | VAL408 |
| J | SER409 |
| J | ASN412 |
| J | GLY425 |
| J | ASP426 |
| J | ALA427 |
| J | GLN501 |
| J | MET502 |
| J | SER519 |
| J | GLY520 |
| J | GLY521 |
| site_id | AF4 |
| Number of Residues | 13 |
| Details | binding site for residue 60G J 704 |
| Chain | Residue |
| I | GLY116 |
| I | ALA117 |
| I | VAL191 |
| I | PRO192 |
| I | ALA200 |
| I | PHE201 |
| I | LYS251 |
| J | MET354 |
| J | ASP379 |
| J | ARG380 |
| J | MET582 |
| J | VAL583 |
| J | TRP586 |
| site_id | AF5 |
| Number of Residues | 14 |
| Details | binding site for residue ATP K 401 |
| Chain | Residue |
| G | VAL237 |
| G | ASP238 |
| G | ILE239 |
| H | ARG159 |
| H | LYS251 |
| H | ARG254 |
| H | ARG280 |
| H | ATP401 |
| H | MG402 |
| K | ASN231 |
| K | PHE232 |
| K | LYS251 |
| K | ARG254 |
| K | ALA257 |
| site_id | AF6 |
| Number of Residues | 14 |
| Details | binding site for residue ATP L 401 |
| Chain | Residue |
| L | ASN231 |
| L | PHE232 |
| L | LYS251 |
| L | ARG254 |
| L | ALA257 |
| L | MG402 |
| O | ARG159 |
| O | LYS251 |
| O | ARG254 |
| O | ARG280 |
| O | ATP401 |
| P | VAL237 |
| P | ASP238 |
| P | ILE239 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue MG L 402 |
| Chain | Residue |
| L | ARG254 |
| L | ATP401 |
| O | ATP401 |
| site_id | AF8 |
| Number of Residues | 21 |
| Details | binding site for residue TPP M 701 |
| Chain | Residue |
| M | VAL497 |
| M | GLY498 |
| M | GLN499 |
| M | HIS500 |
| M | GLY523 |
| M | MET525 |
| M | ASP550 |
| M | ALA551 |
| M | SER552 |
| M | ASN577 |
| M | GLU579 |
| M | GLN580 |
| M | GLY581 |
| M | MET582 |
| M | VAL583 |
| M | MG702 |
| N | TYR113 |
| N | PRO114 |
| N | GLU139 |
| N | PRO165 |
| N | GLN202 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue MG M 702 |
| Chain | Residue |
| M | ASP550 |
| M | ASN577 |
| M | GLU579 |
| M | TPP701 |
| site_id | AG1 |
| Number of Residues | 32 |
| Details | binding site for residue FAD M 703 |
| Chain | Residue |
| M | ASP180 |
| M | ARG241 |
| M | GLY307 |
| M | ALA308 |
| M | GLY309 |
| M | ASN312 |
| M | THR334 |
| M | LEU335 |
| M | GLN336 |
| M | LEU352 |
| M | GLY353 |
| M | MET354 |
| M | HIS355 |
| M | GLY374 |
| M | ALA375 |
| M | ARG376 |
| M | ASP378 |
| M | ARG380 |
| M | VAL381 |
| M | GLU407 |
| M | VAL408 |
| M | SER409 |
| M | ASN412 |
| M | ASP426 |
| M | ALA427 |
| M | GLN501 |
| M | MET502 |
| M | SER519 |
| M | GLY520 |
| M | GLY521 |
| N | PHE201 |
| N | 60G704 |
| site_id | AG2 |
| Number of Residues | 20 |
| Details | binding site for residue TPP N 701 |
| Chain | Residue |
| M | PRO114 |
| M | GLU139 |
| M | PRO165 |
| M | ASN169 |
| M | GLN202 |
| N | VAL497 |
| N | HIS500 |
| N | GLY523 |
| N | MET525 |
| N | GLY549 |
| N | ASP550 |
| N | ALA551 |
| N | SER552 |
| N | ASN577 |
| N | GLU579 |
| N | GLN580 |
| N | GLY581 |
| N | VAL583 |
| N | MG702 |
| N | HOH802 |
| site_id | AG3 |
| Number of Residues | 4 |
| Details | binding site for residue MG N 702 |
| Chain | Residue |
| N | ASP550 |
| N | ASN577 |
| N | GLU579 |
| N | TPP701 |
| site_id | AG4 |
| Number of Residues | 30 |
| Details | binding site for residue FAD N 703 |
| Chain | Residue |
| M | PHE201 |
| N | ASP180 |
| N | ARG241 |
| N | GLY307 |
| N | ALA308 |
| N | GLY309 |
| N | ASN312 |
| N | THR334 |
| N | LEU335 |
| N | LEU352 |
| N | GLY353 |
| N | MET354 |
| N | HIS355 |
| N | GLY374 |
| N | ALA375 |
| N | ARG376 |
| N | ASP378 |
| N | ARG380 |
| N | VAL381 |
| N | GLU407 |
| N | VAL408 |
| N | ASN412 |
| N | ASP426 |
| N | ALA427 |
| N | GLN501 |
| N | MET502 |
| N | SER519 |
| N | GLY520 |
| N | GLY521 |
| N | 60G705 |
| site_id | AG5 |
| Number of Residues | 14 |
| Details | binding site for residue 60G N 704 |
| Chain | Residue |
| M | MET354 |
| M | ASP379 |
| M | ARG380 |
| M | MET582 |
| M | VAL583 |
| M | TRP586 |
| M | FAD703 |
| N | GLY116 |
| N | ALA117 |
| N | VAL191 |
| N | PRO192 |
| N | PHE201 |
| N | GLN202 |
| N | LYS251 |
| site_id | AG6 |
| Number of Residues | 13 |
| Details | binding site for residue 60G N 705 |
| Chain | Residue |
| M | GLY116 |
| M | ALA117 |
| M | VAL191 |
| M | PRO192 |
| M | ALA200 |
| M | PHE201 |
| M | LYS251 |
| N | MET354 |
| N | ARG380 |
| N | MET582 |
| N | VAL583 |
| N | TRP586 |
| N | FAD703 |
| site_id | AG7 |
| Number of Residues | 14 |
| Details | binding site for residue ATP O 401 |
| Chain | Residue |
| K | VAL237 |
| K | ASP238 |
| K | ILE239 |
| L | ARG159 |
| L | LYS251 |
| L | ARG254 |
| L | ARG280 |
| L | ATP401 |
| L | MG402 |
| O | ASN231 |
| O | PHE232 |
| O | LYS251 |
| O | ARG254 |
| O | ALA257 |
| site_id | AG8 |
| Number of Residues | 13 |
| Details | binding site for residue ATP P 401 |
| Chain | Residue |
| C | ARG159 |
| C | LYS251 |
| C | ARG254 |
| C | ARG280 |
| C | ATP401 |
| C | MG402 |
| D | ASP238 |
| D | ILE239 |
| P | ASN231 |
| P | PHE232 |
| P | LYS251 |
| P | ARG254 |
| P | ALA257 |
| site_id | AG9 |
| Number of Residues | 21 |
| Details | binding site for residue TPP Q 701 |
| Chain | Residue |
| Q | VAL497 |
| Q | GLY498 |
| Q | GLN499 |
| Q | HIS500 |
| Q | GLY523 |
| Q | MET525 |
| Q | ASP550 |
| Q | ALA551 |
| Q | SER552 |
| Q | GLU579 |
| Q | GLN580 |
| Q | GLY581 |
| Q | MET582 |
| Q | VAL583 |
| Q | MG702 |
| Q | 60G704 |
| R | PRO114 |
| R | GLU139 |
| R | PRO165 |
| R | ASN169 |
| R | GLN202 |
| site_id | AH1 |
| Number of Residues | 4 |
| Details | binding site for residue MG Q 702 |
| Chain | Residue |
| Q | ASP550 |
| Q | LEU575 |
| Q | GLU579 |
| Q | TPP701 |
| site_id | AH2 |
| Number of Residues | 33 |
| Details | binding site for residue FAD Q 703 |
| Chain | Residue |
| Q | ASP180 |
| Q | ARG241 |
| Q | GLY307 |
| Q | ALA308 |
| Q | GLY309 |
| Q | ASN312 |
| Q | THR334 |
| Q | LEU335 |
| Q | GLN336 |
| Q | LEU352 |
| Q | GLY353 |
| Q | MET354 |
| Q | HIS355 |
| Q | GLY374 |
| Q | ALA375 |
| Q | ARG376 |
| Q | ASP378 |
| Q | ARG380 |
| Q | VAL381 |
| Q | GLU407 |
| Q | VAL408 |
| Q | SER409 |
| Q | ASN412 |
| Q | GLY425 |
| Q | ASP426 |
| Q | ALA427 |
| Q | GLN501 |
| Q | MET502 |
| Q | SER519 |
| Q | GLY520 |
| Q | GLY521 |
| Q | 60G704 |
| R | PHE201 |
| site_id | AH3 |
| Number of Residues | 13 |
| Details | binding site for residue 60G Q 704 |
| Chain | Residue |
| Q | MET354 |
| Q | ASP379 |
| Q | ARG380 |
| Q | MET582 |
| Q | TRP586 |
| Q | TPP701 |
| Q | FAD703 |
| R | GLY116 |
| R | ALA117 |
| R | VAL191 |
| R | PRO192 |
| R | PHE201 |
| R | LYS251 |
| site_id | AH4 |
| Number of Residues | 18 |
| Details | binding site for residue FAD R 701 |
| Chain | Residue |
| Q | PHE201 |
| R | ASP180 |
| R | ARG241 |
| R | GLY309 |
| R | ASN312 |
| R | THR334 |
| R | LEU335 |
| R | GLN336 |
| R | GLY374 |
| R | ARG376 |
| R | ASP378 |
| R | ARG380 |
| R | VAL381 |
| R | GLU407 |
| R | VAL408 |
| R | ASN412 |
| R | ASP426 |
| R | ALA427 |
| site_id | AH5 |
| Number of Residues | 11 |
| Details | binding site for residue 60G R 702 |
| Chain | Residue |
| Q | GLY116 |
| Q | ALA117 |
| Q | VAL191 |
| Q | PRO192 |
| Q | PHE201 |
| Q | GLN202 |
| Q | LYS251 |
| R | ASP379 |
| R | ARG380 |
| R | VAL583 |
| R | TRP586 |
| site_id | AH6 |
| Number of Residues | 12 |
| Details | binding site for residue ATP S 401 |
| Chain | Residue |
| S | ARG159 |
| S | ASN231 |
| S | PHE232 |
| S | LYS251 |
| S | LYS251 |
| S | ARG254 |
| S | ARG254 |
| S | ALA257 |
| S | ARG280 |
| T | VAL237 |
| T | ASP238 |
| T | ILE239 |
| site_id | AH7 |
| Number of Residues | 13 |
| Details | binding site for residue ATP T 401 |
| Chain | Residue |
| T | ASN231 |
| T | PHE232 |
| T | LYS251 |
| T | ARG254 |
| W | ARG159 |
| W | LYS251 |
| W | ARG254 |
| W | ARG280 |
| W | ATP402 |
| W | MG403 |
| X | VAL237 |
| X | ASP238 |
| X | ILE239 |
| site_id | AH8 |
| Number of Residues | 23 |
| Details | binding site for residue TPP U 701 |
| Chain | Residue |
| U | VAL497 |
| U | GLY498 |
| U | GLN499 |
| U | HIS500 |
| U | GLY523 |
| U | MET525 |
| U | GLY549 |
| U | ASP550 |
| U | ALA551 |
| U | SER552 |
| U | ASN577 |
| U | GLU579 |
| U | GLN580 |
| U | GLY581 |
| U | VAL583 |
| U | MG702 |
| V | TYR113 |
| V | PRO114 |
| V | GLU139 |
| V | THR162 |
| V | PRO165 |
| V | ASN169 |
| V | GLN202 |
| site_id | AH9 |
| Number of Residues | 4 |
| Details | binding site for residue MG U 702 |
| Chain | Residue |
| U | ASP550 |
| U | ASN577 |
| U | GLU579 |
| U | TPP701 |
| site_id | AI1 |
| Number of Residues | 32 |
| Details | binding site for residue FAD U 703 |
| Chain | Residue |
| U | ALA179 |
| U | ASP180 |
| U | ARG241 |
| U | GLY307 |
| U | ALA308 |
| U | GLY309 |
| U | ASN312 |
| U | THR334 |
| U | LEU335 |
| U | GLN336 |
| U | LEU352 |
| U | MET354 |
| U | HIS355 |
| U | GLY374 |
| U | ALA375 |
| U | ARG376 |
| U | ASP378 |
| U | ARG380 |
| U | VAL381 |
| U | GLU407 |
| U | VAL408 |
| U | SER409 |
| U | ASN412 |
| U | ASP426 |
| U | ALA427 |
| U | GLN501 |
| U | MET502 |
| U | SER519 |
| U | GLY520 |
| U | GLY521 |
| U | 60G704 |
| V | PHE201 |
| site_id | AI2 |
| Number of Residues | 13 |
| Details | binding site for residue 60G U 704 |
| Chain | Residue |
| U | MET354 |
| U | ASP379 |
| U | ARG380 |
| U | MET582 |
| U | TRP586 |
| U | FAD703 |
| V | GLY116 |
| V | ALA117 |
| V | VAL191 |
| V | PRO192 |
| V | ALA200 |
| V | PHE201 |
| V | LYS251 |
| site_id | AI3 |
| Number of Residues | 22 |
| Details | binding site for residue TPP V 701 |
| Chain | Residue |
| U | TYR113 |
| U | PRO114 |
| U | GLU139 |
| U | THR162 |
| U | PRO165 |
| U | ASN169 |
| U | GLN202 |
| V | VAL497 |
| V | GLN499 |
| V | HIS500 |
| V | GLY523 |
| V | MET525 |
| V | ASP550 |
| V | ALA551 |
| V | SER552 |
| V | ASN577 |
| V | GLU579 |
| V | GLN580 |
| V | GLY581 |
| V | MET582 |
| V | VAL583 |
| V | MG702 |
| site_id | AI4 |
| Number of Residues | 6 |
| Details | binding site for residue MG V 702 |
| Chain | Residue |
| V | GLY549 |
| V | ASP550 |
| V | LEU575 |
| V | ASN577 |
| V | GLU579 |
| V | TPP701 |
| site_id | AI5 |
| Number of Residues | 30 |
| Details | binding site for residue FAD V 703 |
| Chain | Residue |
| U | PHE201 |
| V | ASP180 |
| V | ARG241 |
| V | GLY307 |
| V | ALA308 |
| V | GLY309 |
| V | ASN312 |
| V | THR334 |
| V | LEU335 |
| V | GLN336 |
| V | LEU352 |
| V | GLY353 |
| V | MET354 |
| V | HIS355 |
| V | GLY374 |
| V | ARG376 |
| V | ASP378 |
| V | ARG380 |
| V | VAL381 |
| V | GLU407 |
| V | VAL408 |
| V | ASN412 |
| V | GLY425 |
| V | ASP426 |
| V | ALA427 |
| V | GLN501 |
| V | MET502 |
| V | GLY520 |
| V | GLY521 |
| V | 60G704 |
| site_id | AI6 |
| Number of Residues | 12 |
| Details | binding site for residue 60G V 704 |
| Chain | Residue |
| U | GLY116 |
| U | ALA117 |
| U | VAL191 |
| U | PRO192 |
| U | PHE201 |
| U | LYS251 |
| V | MET354 |
| V | ASP379 |
| V | ARG380 |
| V | MET582 |
| V | TRP586 |
| V | FAD703 |
| site_id | AI7 |
| Number of Residues | 12 |
| Details | binding site for residue ATP W 401 |
| Chain | Residue |
| W | VAL237 |
| W | ASP238 |
| W | ILE239 |
| X | ARG159 |
| X | ASN231 |
| X | PHE232 |
| X | LYS251 |
| X | LYS251 |
| X | ARG254 |
| X | ARG254 |
| X | ALA257 |
| X | ARG280 |
| site_id | AI8 |
| Number of Residues | 14 |
| Details | binding site for residue ATP W 402 |
| Chain | Residue |
| S | VAL237 |
| S | ASP238 |
| S | ILE239 |
| T | ARG159 |
| T | LYS251 |
| T | ARG254 |
| T | ARG280 |
| T | ATP401 |
| W | ASN231 |
| W | PHE232 |
| W | LYS251 |
| W | ARG254 |
| W | ALA257 |
| W | MG403 |
| site_id | AI9 |
| Number of Residues | 3 |
| Details | binding site for residue MG W 403 |
| Chain | Residue |
| T | ATP401 |
| W | ARG254 |
| W | ATP402 |
Functional Information from PROSITE/UniProt
| site_id | PS00187 |
| Number of Residues | 20 |
| Details | TPP_ENZYMES Thiamine pyrophosphate enzymes signature. IGaqvakPeslvIdIdGDAS |
| Chain | Residue | Details |
| A | ILE533-SER552 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU139 | |
| E | ASP550 | |
| E | ASN577 | |
| E | GLU579 | |
| F | GLU139 | |
| F | ASP550 | |
| F | ASN577 | |
| F | GLU579 | |
| I | GLU139 | |
| I | ASP550 | |
| I | ASN577 | |
| A | ASP550 | |
| I | GLU579 | |
| J | GLU139 | |
| J | ASP550 | |
| J | ASN577 | |
| J | GLU579 | |
| M | GLU139 | |
| M | ASP550 | |
| M | ASN577 | |
| M | GLU579 | |
| N | GLU139 | |
| A | ASN577 | |
| N | ASP550 | |
| N | ASN577 | |
| N | GLU579 | |
| Q | GLU139 | |
| Q | ASP550 | |
| Q | ASN577 | |
| Q | GLU579 | |
| R | GLU139 | |
| R | ASP550 | |
| R | ASN577 | |
| A | GLU579 | |
| R | GLU579 | |
| U | GLU139 | |
| U | ASP550 | |
| U | ASN577 | |
| U | GLU579 | |
| V | GLU139 | |
| V | ASP550 | |
| V | ASN577 | |
| V | GLU579 | |
| B | GLU139 | |
| B | ASP550 | |
| B | ASN577 | |
| B | GLU579 | |
| E | GLU139 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 36 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12496246 |
| Chain | Residue | Details |
| A | ARG241 | |
| F | ARG241 | |
| F | HIS355 | |
| F | GLU407 | |
| I | ARG241 | |
| I | HIS355 | |
| I | GLU407 | |
| J | ARG241 | |
| J | HIS355 | |
| J | GLU407 | |
| M | ARG241 | |
| A | HIS355 | |
| M | HIS355 | |
| M | GLU407 | |
| N | ARG241 | |
| N | HIS355 | |
| N | GLU407 | |
| Q | ARG241 | |
| Q | HIS355 | |
| Q | GLU407 | |
| R | ARG241 | |
| R | HIS355 | |
| A | GLU407 | |
| R | GLU407 | |
| U | ARG241 | |
| U | HIS355 | |
| U | GLU407 | |
| V | ARG241 | |
| V | HIS355 | |
| V | GLU407 | |
| B | ARG241 | |
| B | HIS355 | |
| B | GLU407 | |
| E | ARG241 | |
| E | HIS355 | |
| E | GLU407 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| A | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | PHE201 | single electron acceptor, single electron donor, single electron relay |
| A | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| A | LYS251 | steric locator |
| A | MET582 | polar interaction, steric role |
| site_id | MCSA10 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| R | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| R | PHE201 | single electron acceptor, single electron donor, single electron relay |
| R | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| R | LYS251 | steric locator |
| R | MET582 | polar interaction, steric role |
| site_id | MCSA11 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| U | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| U | PHE201 | single electron acceptor, single electron donor, single electron relay |
| U | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| U | LYS251 | steric locator |
| U | MET582 | polar interaction, steric role |
| site_id | MCSA12 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| V | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| V | PHE201 | single electron acceptor, single electron donor, single electron relay |
| V | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| V | LYS251 | steric locator |
| V | MET582 | polar interaction, steric role |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| B | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | PHE201 | single electron acceptor, single electron donor, single electron relay |
| B | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| B | LYS251 | steric locator |
| B | MET582 | polar interaction, steric role |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| E | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| E | PHE201 | single electron acceptor, single electron donor, single electron relay |
| E | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| E | LYS251 | steric locator |
| E | MET582 | polar interaction, steric role |
| site_id | MCSA4 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| F | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| F | PHE201 | single electron acceptor, single electron donor, single electron relay |
| F | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| F | LYS251 | steric locator |
| F | MET582 | polar interaction, steric role |
| site_id | MCSA5 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| I | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| I | PHE201 | single electron acceptor, single electron donor, single electron relay |
| I | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| I | LYS251 | steric locator |
| I | MET582 | polar interaction, steric role |
| site_id | MCSA6 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| J | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| J | PHE201 | single electron acceptor, single electron donor, single electron relay |
| J | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| J | LYS251 | steric locator |
| J | MET582 | polar interaction, steric role |
| site_id | MCSA7 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| M | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| M | PHE201 | single electron acceptor, single electron donor, single electron relay |
| M | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| M | LYS251 | steric locator |
| M | MET582 | polar interaction, steric role |
| site_id | MCSA8 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| N | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| N | PHE201 | single electron acceptor, single electron donor, single electron relay |
| N | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| N | LYS251 | steric locator |
| N | MET582 | polar interaction, steric role |
| site_id | MCSA9 |
| Number of Residues | 5 |
| Details | M-CSA 289 |
| Chain | Residue | Details |
| Q | GLU139 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| Q | PHE201 | single electron acceptor, single electron donor, single electron relay |
| Q | GLN202 | electrostatic stabiliser, hydrogen bond donor |
| Q | LYS251 | steric locator |
| Q | MET582 | polar interaction, steric role |
