Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 501 |
| Chain | Residue |
| A | ASP60 |
| A | HOH615 |
| A | HOH632 |
| A | HOH657 |
| A | HOH660 |
| A | HOH675 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 502 |
| Chain | Residue |
| A | HOH696 |
| B | ARG41 |
| A | THR74 |
| A | ASN88 |
| A | HOH616 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 503 |
| Chain | Residue |
| A | LYS7 |
| A | ARG8 |
| A | HOH697 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 504 |
| Chain | Residue |
| A | GLY51 |
| A | PHE53 |
| A | HOH645 |
| B | GLY51 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | GLN18 |
| A | MET36 |
| A | SER37 |
| A | HOH635 |
| A | HOH703 |
| B | THR12 |
| B | GLU65 |
| B | ALA67 |
| B | GLY68 |
| B | HOH386 |
| site_id | AC6 |
| Number of Residues | 33 |
| Details | binding site for residue Q1D B 201 |
| Chain | Residue |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | HOH623 |
| A | HOH659 |
| A | HOH682 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | ILE47 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| B | PRO81 |
| B | VAL82 |
| B | ILE84 |
| B | HOH302 |
| B | HOH326 |
| B | HOH327 |
| B | HOH372 |
| B | HOH375 |
| B | HOH409 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 202 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 203 |
| Chain | Residue |
| B | THR74 |
| B | ASN88 |
| B | HOH333 |
| B | HOH402 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
