6U78
Rv3722c in complex with glutamic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004069 | molecular_function | L-aspartate:2-oxoglutarate aminotransferase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0016740 | molecular_function | transferase activity |
| B | 0004069 | molecular_function | L-aspartate:2-oxoglutarate aminotransferase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0016740 | molecular_function | transferase activity |
| C | 0004069 | molecular_function | L-aspartate:2-oxoglutarate aminotransferase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0016740 | molecular_function | transferase activity |
| D | 0004069 | molecular_function | L-aspartate:2-oxoglutarate aminotransferase activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0008483 | molecular_function | transaminase activity |
| D | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue PLP A 501 |
| Chain | Residue |
| A | SER100 |
| A | SER256 |
| A | LYS257 |
| A | HOH607 |
| C | TYR69 |
| A | LEU101 |
| A | TYR139 |
| A | VAL184 |
| A | ASN189 |
| A | ASP218 |
| A | ALA220 |
| A | TYR221 |
| A | SER254 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue PLP B 501 |
| Chain | Residue |
| B | SER99 |
| B | SER100 |
| B | LEU101 |
| B | TYR139 |
| B | VAL184 |
| B | ASN189 |
| B | ASP218 |
| B | ALA220 |
| B | TYR221 |
| B | SER254 |
| B | SER256 |
| B | LYS257 |
| B | GLU502 |
| D | TYR69 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GLU B 502 |
| Chain | Residue |
| B | GLY37 |
| B | TYR139 |
| B | ARG141 |
| B | PHE349 |
| B | ARG392 |
| B | PLP501 |
| D | TYR69 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 503 |
| Chain | Residue |
| B | GLN72 |
| B | HIS73 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| B | PHE300 |
| B | PHE301 |
| B | GLY306 |
| B | LEU309 |
| B | ARG313 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 501 |
| Chain | Residue |
| D | GLY71 |
| D | GLN72 |
| D | HIS73 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide PLP C 501 and LYS C 257 |
| Chain | Residue |
| A | TYR69 |
| C | SER99 |
| C | SER100 |
| C | LEU101 |
| C | TYR139 |
| C | ASN189 |
| C | ASP218 |
| C | ALA220 |
| C | TYR221 |
| C | SER254 |
| C | THR255 |
| C | SER256 |
| C | ILE258 |
| C | TYR348 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide PLP D 502 and LYS D 257 |
| Chain | Residue |
| B | TYR69 |
| D | SER99 |
| D | SER100 |
| D | LEU101 |
| D | TYR139 |
| D | ASN189 |
| D | ASP218 |
| D | ALA220 |
| D | TYR221 |
| D | HIS224 |
| D | SER254 |
| D | THR255 |
| D | SER256 |
| D | ILE258 |
| D | TYR348 |
| D | HOH619 |
| D | HOH634 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32327655","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2015","submissionDatabase":"PDB data bank","title":"Rv3722c aminotransferase from Mycobacterium tuberculosis.","authoringGroup":["Structures of Mtb proteins conferring susceptibility to known Mtb inhibitors (MTBI)"],"authors":["Osipiuk J.","Hatzos-Skintges C.","Jedrzejczak R.","Babnigg G.","Sacchettini J.","Joachimiak A."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32327655","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
