Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
| C | 0042981 | biological_process | regulation of apoptotic process |
| D | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue Q0A A 401 |
| Chain | Residue |
| A | MET231 |
| B | THR226 |
| B | ALA227 |
| B | GLY230 |
| B | ARG233 |
| B | Q0A401 |
| B | HOH518 |
| A | LEU235 |
| A | MET250 |
| A | VAL253 |
| A | ARG263 |
| A | THR266 |
| A | LEU267 |
| A | PHE270 |
| A | LEU290 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | GLY311 |
| A | HOH502 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | ASN260 |
| A | TRP261 |
| A | TRP305 |
| A | GLN309 |
| D | SER255 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | ASN282 |
| A | GLN283 |
| A | GLU284 |
| A | SER285 |
| B | ILE281 |
| B | ASN282 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | ARG207 |
| A | GLU211 |
| A | ARG214 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue Q0A B 401 |
| Chain | Residue |
| A | THR226 |
| A | ALA227 |
| A | GLY230 |
| A | ARG233 |
| A | Q0A401 |
| B | MET231 |
| B | LEU235 |
| B | MET250 |
| B | VAL253 |
| B | ARG263 |
| B | THR266 |
| B | LEU267 |
| B | LEU290 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 402 |
| Chain | Residue |
| A | ASP304 |
| B | THR259 |
| B | THR301 |
| B | LYS302 |
| B | ASP304 |
| B | TRP305 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 403 |
| Chain | Residue |
| B | LEU232 |
| B | ASP236 |
| B | ILE237 |
| B | HOH524 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | TYR185 |
| B | GLU188 |
| B | GLN189 |
| B | ARG214 |
| B | ASP218 |
| site_id | AD1 |
| Number of Residues | 14 |
| Details | binding site for residue Q0A C 401 |
| Chain | Residue |
| C | MET231 |
| C | LEU235 |
| C | MET250 |
| C | ARG263 |
| C | THR266 |
| C | LEU267 |
| C | PHE270 |
| C | LEU290 |
| D | THR226 |
| D | ALA227 |
| D | GLY230 |
| D | ARG233 |
| D | Q0A401 |
| D | HOH508 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ACT C 402 |
| Chain | Residue |
| C | GLN229 |
| C | PHE273 |
| C | LYS276 |
| C | HIS277 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 405 |
| Chain | Residue |
| C | GLU173 |
| C | ARG176 |
| C | GLU180 |
| C | GLY200 |
| C | ARG201 |
| site_id | AD4 |
| Number of Residues | 14 |
| Details | binding site for residue Q0A D 401 |
| Chain | Residue |
| C | THR226 |
| C | ALA227 |
| C | GLY230 |
| C | MET231 |
| C | Q0A401 |
| D | MET231 |
| D | ARG263 |
| D | THR266 |
| D | LEU267 |
| D | PHE270 |
| D | GLY271 |
| D | VAL274 |
| D | LEU290 |
| D | EDO403 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT D 402 |
| Chain | Residue |
| A | GLU288 |
| D | THR196 |
| D | PRO198 |
| A | ARG187 |
| A | THR191 |
| A | GLU284 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 403 |
| Chain | Residue |
| C | THR226 |
| C | GLN229 |
| C | GLY230 |
| D | VAL258 |
| D | ASN260 |
| D | ARG263 |
| D | Q0A401 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 20 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA |
| Chain | Residue | Details |
| A | VAL253-ALA272 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV |
| Chain | Residue | Details |
| A | TRP305-VAL316 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN |
| Chain | Residue | Details |
| A | ALA209-ASN223 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) |
| Chain | Residue | Details |
| C | LYS197 | |
| D | LYS194 | |
| D | LYS197 | |
| A | LYS194 | |
| A | LYS197 | |
| B | LYS194 | |
| B | LYS197 | |
| C | LYS194 | |
