Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6U5P

Calcium-bound MthK gating ring state 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006813	biological_process	potassium ion transport
A	0008324	molecular_function	monoatomic cation transmembrane transporter activity
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0098655	biological_process	monoatomic cation transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0006813	biological_process	potassium ion transport
B	0008324	molecular_function	monoatomic cation transmembrane transporter activity
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0098655	biological_process	monoatomic cation transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0006813	biological_process	potassium ion transport
C	0008324	molecular_function	monoatomic cation transmembrane transporter activity
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0098655	biological_process	monoatomic cation transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0006813	biological_process	potassium ion transport
D	0008324	molecular_function	monoatomic cation transmembrane transporter activity
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0098655	biological_process	monoatomic cation transmembrane transport
E	0005886	cellular_component	plasma membrane
E	0006813	biological_process	potassium ion transport
E	0008324	molecular_function	monoatomic cation transmembrane transporter activity
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
E	0098655	biological_process	monoatomic cation transmembrane transport
F	0005886	cellular_component	plasma membrane
F	0006813	biological_process	potassium ion transport
F	0008324	molecular_function	monoatomic cation transmembrane transporter activity
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
F	0098655	biological_process	monoatomic cation transmembrane transport
G	0005886	cellular_component	plasma membrane
G	0006813	biological_process	potassium ion transport
G	0008324	molecular_function	monoatomic cation transmembrane transporter activity
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
G	0098655	biological_process	monoatomic cation transmembrane transport
H	0005886	cellular_component	plasma membrane
H	0006813	biological_process	potassium ion transport
H	0008324	molecular_function	monoatomic cation transmembrane transporter activity
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
H	0098655	biological_process	monoatomic cation transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CA A 401

Chain	Residue
A	ASP184
A	GLU210

site_id	AC2
Number of Residues	4
Details	binding site for residue CA A 402

Chain	Residue
A	ARG241
A	ASP245
A	GLU248
E	GLU266

site_id	AC3
Number of Residues	3
Details	binding site for residue CA A 403

Chain	Residue
A	GLY290
A	GLU326
E	ASP305

site_id	AC4
Number of Residues	3
Details	binding site for residue CA E 401

Chain	Residue
A	ASP305
E	GLY290
E	GLU326

site_id	AC5
Number of Residues	4
Details	binding site for residue CA E 402

Chain	Residue
E	ASP184
E	GLU210
E	GLU212
E	HOH501

site_id	AC6
Number of Residues	4
Details	binding site for residue CA E 403

Chain	Residue
A	GLU266
E	ARG241
E	ASP245
E	GLU248

site_id	AC7
Number of Residues	4
Details	binding site for residue CA B 401

Chain	Residue
B	SER124
B	ASP184
B	GLU210
B	GLU212

site_id	AC8
Number of Residues	4
Details	binding site for residue CA B 402

Chain	Residue
B	ARG241
B	ASP245
B	GLU248
F	GLU266

site_id	AC9
Number of Residues	3
Details	binding site for residue CA B 403

Chain	Residue
B	GLU266
F	ARG241
F	ASP245

site_id	AD1
Number of Residues	3
Details	binding site for residue CA B 404

Chain	Residue
B	GLY290
B	GLU326
F	ASP305

site_id	AD2
Number of Residues	3
Details	binding site for residue CA F 401

Chain	Residue
B	ASP305
F	GLY290
F	GLU326

site_id	AD3
Number of Residues	3
Details	binding site for residue CA F 402

Chain	Residue
F	SER124
F	ASP184
F	GLU210

site_id	AD4
Number of Residues	2
Details	binding site for residue CA C 401

Chain	Residue
C	ASP184
C	GLU210

site_id	AD5
Number of Residues	4
Details	binding site for residue CA C 402

Chain	Residue
C	ARG241
C	ASP245
C	GLU248
G	GLU266

site_id	AD6
Number of Residues	3
Details	binding site for residue CA C 403

Chain	Residue
C	GLY290
C	GLU326
G	ASP305

site_id	AD7
Number of Residues	3
Details	binding site for residue CA G 401

Chain	Residue
C	ASP305
G	GLY290
G	GLU326

site_id	AD8
Number of Residues	4
Details	binding site for residue CA G 402

Chain	Residue
G	ASP184
G	GLU210
G	GLU212
G	HOH501

site_id	AD9
Number of Residues	4
Details	binding site for residue CA G 403

Chain	Residue
C	GLU266
G	ARG241
G	ASP245
G	GLU248

site_id	AE1
Number of Residues	4
Details	binding site for residue CA D 401

Chain	Residue
D	SER124
D	ASP184
D	GLU210
D	GLU212

site_id	AE2
Number of Residues	4
Details	binding site for residue CA D 402

Chain	Residue
D	ARG241
D	ASP245
D	GLU248
H	GLU266

site_id	AE3
Number of Residues	3
Details	binding site for residue CA D 403

Chain	Residue
D	GLU266
H	ARG241
H	ASP245

site_id	AE4
Number of Residues	3
Details	binding site for residue CA D 404

Chain	Residue
D	GLY290
D	GLU326
H	ASP305

site_id	AE5
Number of Residues	3
Details	binding site for residue CA H 401

Chain	Residue
D	ASP305
H	GLY290
H	GLU326

site_id	AE6
Number of Residues	3
Details	binding site for residue CA H 402

Chain	Residue
H	SER124
H	ASP184
H	GLU210

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	232
Details	TOPO_DOM: Cytoplasmic

Chain	Residue	Details
A	MET1-ALA20
C	GLU96-LEU106
G	MET1-ALA20
G	GLU96-LEU106
D	MET1-ALA20
D	GLU96-LEU106
H	MET1-ALA20
H	GLU96-LEU106
A	GLU96-LEU106
E	MET1-ALA20
E	GLU96-LEU106
B	MET1-ALA20
B	GLU96-LEU106
F	MET1-ALA20
F	GLU96-LEU106
C	MET1-ALA20

site_id	SWS_FT_FI2
Number of Residues	160
Details	TRANSMEM: Helical; Name=Outer helix M1

Chain	Residue	Details
A	THR21-ILE41
E	THR21-ILE41
B	THR21-ILE41
F	THR21-ILE41
C	THR21-ILE41
G	THR21-ILE41
D	THR21-ILE41
H	THR21-ILE41

site_id	SWS_FT_FI3
Number of Residues	80
Details	TOPO_DOM: Extracellular

Chain	Residue	Details
A	GLU42-VAL48
C	TYR65-THR69
G	GLU42-VAL48
G	TYR65-THR69
D	GLU42-VAL48
D	TYR65-THR69
H	GLU42-VAL48
H	TYR65-THR69
A	TYR65-THR69
E	GLU42-VAL48
E	TYR65-THR69
B	GLU42-VAL48
B	TYR65-THR69
F	GLU42-VAL48
F	TYR65-THR69
C	GLU42-VAL48

site_id	SWS_FT_FI4
Number of Residues	72
Details	INTRAMEM: Helical; Pore-forming => ECO:0000255

Chain	Residue	Details
A	SER49-ALA58
E	SER49-ALA58
B	SER49-ALA58
F	SER49-ALA58
C	SER49-ALA58
G	SER49-ALA58
D	SER49-ALA58
H	SER49-ALA58

site_id	SWS_FT_FI5
Number of Residues	40
Details	INTRAMEM: Pore-forming => ECO:0000255

Chain	Residue	Details
A	THR59-ASP64
E	THR59-ASP64
B	THR59-ASP64
F	THR59-ASP64
C	THR59-ASP64
G	THR59-ASP64
D	THR59-ASP64
H	THR59-ASP64

site_id	SWS_FT_FI6
Number of Residues	200
Details	TRANSMEM: Helical; Name=Inner helix M2

Chain	Residue	Details
A	PRO70-LEU95
E	PRO70-LEU95
B	PRO70-LEU95
F	PRO70-LEU95
C	PRO70-LEU95
G	PRO70-LEU95
D	PRO70-LEU95
H	PRO70-LEU95

site_id	SWS_FT_FI7
Number of Residues	24
Details	BINDING:

Chain	Residue	Details
A	ASP184
F	ASP184
F	GLU210
F	GLU212
C	ASP184
C	GLU210
C	GLU212
G	ASP184
G	GLU210
G	GLU212
D	ASP184
A	GLU210
D	GLU210
D	GLU212
H	ASP184
H	GLU210
H	GLU212
A	GLU212
E	ASP184
E	GLU210
E	GLU212
B	ASP184
B	GLU210
B	GLU212

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)