Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | HIS53 |
| A | GLN54 |
| A | PHE55 |
| B | GLN139 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | HOH308 |
| B | SER99 |
| A | LYS31 |
| A | ARG34 |
| A | TRP96 |
| A | LYS131 |
| A | GLU146 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 201 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 202 |
| Chain | Residue |
| B | VAL26 |
| B | SER27 |
| B | LYS35 |
| B | GLN40 |
| B | ASN44 |
| B | HOH313 |
| B | HOH368 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 203 |
| Chain | Residue |
| B | ASN37 |
| B | GLN40 |
| B | TYR41 |
| B | HOH351 |
| C | TRP1 |
| C | CYS11 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide ACE C 0 and TRP C 1 |
| Chain | Residue |
| A | TRP57 |
| B | ASN37 |
| B | GOL203 |
| C | TRP2 |
| C | ALY9 |
| C | GLY10 |
| C | CYS11 |
| C | HOH107 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide ACE C 0 and CYS C 11 |
| Chain | Residue |
| A | TRP57 |
| A | HOH326 |
| B | PRO141 |
| B | GOL203 |
| C | TRP1 |
| C | ALY9 |
| C | GLY10 |
| C | NH212 |
| C | HOH107 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide PRO C 5 and ALY C 6 |
| Chain | Residue |
| A | VAL63 |
| A | LEU68 |
| A | ASN116 |
| A | ASP120 |
| A | ASP121 |
| A | ILE122 |
| A | HOH316 |
| A | HOH328 |
| C | TRP2 |
| C | ILE4 |
| C | VAL7 |
| C | HOH101 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide ALY C 6 and VAL C 7 |
| Chain | Residue |
| A | VAL63 |
| A | ASN116 |
| A | ASP120 |
| A | ASP121 |
| A | ILE122 |
| A | HOH316 |
| A | HOH328 |
| C | TRP2 |
| C | ILE4 |
| C | PRO5 |
| C | LYS8 |
| C | HOH108 |
| site_id | AD1 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide LYS C 8 and ALY C 9 |
| Chain | Residue |
| A | ASP121 |
| A | MET125 |
| A | GLN142 |
| A | GLU143 |
| A | HOH301 |
| B | GLN142 |
| B | GLU143 |
| C | TRP1 |
| C | TRP2 |
| C | ILE3 |
| C | ILE4 |
| C | VAL7 |
| C | GLY10 |
| C | CYS11 |
| C | HOH103 |
| C | HOH106 |
| site_id | AD2 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide ALY C 9 and GLY C 10 |
| Chain | Residue |
| A | ASP121 |
| A | MET125 |
| A | GLN142 |
| A | GLU143 |
| B | ASN37 |
| B | PRO141 |
| C | TRP1 |
| C | TRP2 |
| C | ILE3 |
| C | LYS8 |
| C | CYS11 |
| C | HOH103 |
| C | HOH106 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide CYS C 11 and NH2 C 12 |
| Chain | Residue |
| B | PRO141 |
| B | GOL203 |
| C | ACE0 |
| C | TRP1 |
| C | ALY9 |
| C | GLY10 |
| A | TRP57 |
| A | HOH326 |
| A | HOH333 |
| site_id | AD4 |
| Number of Residues | 11 |
| Details | binding site for Di-peptide ACE D 0 and CYS D 11 |
| Chain | Residue |
| A | PRO29 |
| A | SER30 |
| B | GLU25 |
| B | TRP57 |
| D | TRP1 |
| D | ALY9 |
| D | GLY10 |
| D | NH212 |
| D | HOH101 |
| D | HOH104 |
| D | HOH107 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for Di-peptide ACE D 0 and TRP D 1 |
| Chain | Residue |
| A | PRO29 |
| A | SER30 |
| A | LYS31 |
| B | TRP57 |
| D | TRP2 |
| D | ILE3 |
| D | ALY9 |
| D | GLY10 |
| D | CYS11 |
| D | HOH101 |
| D | HOH104 |
| site_id | AD6 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide PRO D 5 and ALY D 6 |
| Chain | Residue |
| B | VAL63 |
| B | LEU68 |
| B | ASN116 |
| B | ASP120 |
| B | ASP121 |
| B | ILE122 |
| B | HOH322 |
| B | HOH350 |
| D | TRP2 |
| D | ILE4 |
| D | VAL7 |
| D | HOH102 |
| site_id | AD7 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide ALY D 6 and VAL D 7 |
| Chain | Residue |
| B | VAL63 |
| B | ASN116 |
| B | LYS117 |
| B | ASP120 |
| B | ASP121 |
| B | ILE122 |
| B | HOH322 |
| B | HOH350 |
| D | TRP2 |
| D | ILE4 |
| D | PRO5 |
| D | LYS8 |
| site_id | AD8 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide LYS D 8 and ALY D 9 |
| Chain | Residue |
| A | ASN28 |
| B | SER24 |
| B | GLN54 |
| B | TRP57 |
| B | ASP121 |
| B | MET125 |
| D | TRP1 |
| D | TRP2 |
| D | ILE3 |
| D | ILE4 |
| D | VAL7 |
| D | GLY10 |
| D | CYS11 |
| D | NH212 |
| D | HOH107 |
| site_id | AD9 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide ALY D 9 and GLY D 10 |
| Chain | Residue |
| A | ASN28 |
| B | SER24 |
| B | GLU25 |
| B | GLN54 |
| B | TRP57 |
| B | ASP121 |
| B | MET125 |
| D | TRP1 |
| D | ILE3 |
| D | LYS8 |
| D | CYS11 |
| D | NH212 |
| D | HOH107 |
| site_id | AE1 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide CYS D 11 and NH2 D 12 |
| Chain | Residue |
| A | ASN28 |
| A | PRO29 |
| B | GLU25 |
| B | TRP57 |
| D | ACE0 |
| D | TRP1 |
| D | ALY9 |
| D | GLY10 |
| D | HOH107 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFyqpvDaiklnlpDYHkiIknpMdmgtIkkrlenny..Ywsasecmqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA56-TYR115 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 212 |
| Details | Domain: {"description":"Bromo 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Region: {"description":"Acetylated histone H3 binding","evidences":[{"source":"PubMed","id":"27105114","evidenceCode":"ECO:0000269"}]} |
