6U3G
Best fitting antiparallel model for Volume 2 of truncated dimeric Cytohesin-3 (Grp1; amino acids 14-399)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0001726 | cellular_component | ruffle |
| A | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005547 | molecular_function | phosphatidylinositol-3,4,5-trisphosphate binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005912 | cellular_component | adherens junction |
| A | 0005923 | cellular_component | bicellular tight junction |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0032012 | biological_process | regulation of ARF protein signal transduction |
| A | 0048193 | biological_process | Golgi vesicle transport |
| A | 0090162 | biological_process | establishment of epithelial cell polarity |
| B | 0000139 | cellular_component | Golgi membrane |
| B | 0001726 | cellular_component | ruffle |
| B | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005547 | molecular_function | phosphatidylinositol-3,4,5-trisphosphate binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0005912 | cellular_component | adherens junction |
| B | 0005923 | cellular_component | bicellular tight junction |
| B | 0016192 | biological_process | vesicle-mediated transport |
| B | 0032012 | biological_process | regulation of ARF protein signal transduction |
| B | 0048193 | biological_process | Golgi vesicle transport |
| B | 0090162 | biological_process | establishment of epithelial cell polarity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 4IP A 400 |
| Chain | Residue |
| A | LYS273 |
| A | ARG305 |
| A | LYS343 |
| A | ASN354 |
| A | HIS355 |
| A | GLY275 |
| A | GLY276 |
| A | ARG277 |
| A | VAL278 |
| A | THR280 |
| A | LYS282 |
| A | ARG284 |
| A | TYR295 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue 4IP B 400 |
| Chain | Residue |
| B | LYS273 |
| B | GLY275 |
| B | GLY276 |
| B | ARG277 |
| B | VAL278 |
| B | THR280 |
| B | LYS282 |
| B | ARG284 |
| B | TYR295 |
| B | ARG305 |
| B | LYS343 |
| B | ASN354 |
| B | HIS355 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 258 |
| Details | Domain: {"description":"SEC7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00189","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Region: {"description":"C-terminal autoinhibitory region","evidences":[{"source":"PubMed","id":"23940353","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 94 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23940353","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
